Results 11 to 20 of about 54,422 (163)
The Proximal Tubule and Albuminuria [PDF]
Journal of the American Society of Nephrology, 2014 Recent data highlight the role of the proximal tubule (PT) in reabsorbing, processing, and transcytosing urinary albumin from the glomerular filtrate. Innovative techniques and approaches have provided exciting insights into these processes, and numerous investigators have shown that selective PT cell defects lead to significant albuminuria, even ...
Dickson, Landon E. +3 more
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Stx2 Induces Differential Gene Expression and Disturbs Circadian Rhythm Genes in the Proximal Tubule
Toxins, 2022 Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown.
Fumiko Obata +4 more
doaj +1 more source
TNF-α induces Claudin-1 expression in renal tubules in Alport mice
PLoS ONE, 2022 Claudin-1 (CL-1) is responsible for the paracellular barrier function of glomerular parietal epithelial cells (PEC) in kidneys, but the role of CL-1 in proximal tubules remains to be elucidated.
Manami Iida +7 more
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EFFECTS OF KETAMINE AND DIAZEPAM ON THE MORPHOLOGY OF THE KIDNEY OF RABBIT : AN ELECTRON MICROSCOPIC STUDY [PDF]
Assiut Veterinary Medical Journal, 1995 Three groups of adult Newzeeland white rabbits were used in this study. The first group served as control. The second and third groups were injected intravenously with a single dose of diazepam and ketamine respectively.
FAISAL, I. ZAHIR +3 more
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The Fanconi syndrome of cystinosis: insights into the pathophysiology
The Turkish Journal of Pediatrics, 2002 Cystinosis is a lysosomal storage disease, and is one of the most common causes of the Fanconi syndrome. In vitro studies of the cystine-loaded tubule provided insights into the pathophysiology of the proximal tubular defect.
Abdullah Sakarcan
doaj +1 more source
Alteration of the Kidney Structure of White Rat after Water Administration from Martapura River
Journal of Wetlands Environmental Management, 2021 Martapura River is indicated to have been contaminated by heavy metal can adversely affect the kidneys. This study aims to analyze the impact of water consumption of the Martapura River on the microscopic image of white rat kidneys. Microscopic structure
Ida Yuliana +5 more
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Drug-Induced Nephrotoxicity: A Review [PDF]
المجلة العراقية للصيدلة, 2022 Background: Nephrotoxicity is referred to as rapid degeneration in kidney functioning due to the toxic effects of medications. The glomerulus and proximal renal tubule are the fundamental portions of the nephron to be affected by drugs leading to ...
Muthanna Khalaf, Zeina Althanoon
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Immunohistochemical distributions of hgf and pcna in the kidneys of diabetic and non-diabetic mice [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2020 Diabetes mellitus is a systemic disease that causes functional disorders in various organs and systems. In this study, we investigated the immunohistochemical localization of hepatocyte growth factor (HGF) and proliferating cell nuclear antigen (PCNA) in
Turgay DEPREM +5 more
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Biomolecules & Biomedicine, 2014 The aim of this research was to assess the reactive changes of rat proximal tubules caused by gentamicin and the effect of relatively low doses of melatonin. 48 adult male Wistar rats were distributed into six groups of equal size which all received one
Dina Kapić +3 more
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Scientific Reports, 2018 Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita +4 more
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