Results 41 to 50 of about 54,422 (163)
Redox BiologyThere is a large body of evidence implicating mitochondrial reactive oxygen species (ROS) overproduction and oxidative stress in the development of diabetic kidney disease and the deficiency of mitochondrial antioxidant systems in the kidney, such as ...
Inez A. Trambas +14 more
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BMC Nephrology, 2017 Background Caveolae are membrane invaginations measuring 50–100 nm. These organelles, composed of caveolin and cavin proteins, are important for cellular signaling and survival. Caveolae play incompletely defined roles in human kidneys.
Krzysztof M. Krawczyk +5 more
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EFFECT OF HYPERVITAMINOSIS D ON SOME ORGANS OF THE ALBINO RAT II- KIDNEY [PDF]
Assiut Veterinary Medical Journal, 1991 The effect of hypervitaminosis D on the kidney of the albino rats has been studied. The following results have demonstrated: A) Histological changes: In the postnatal changes: Some convoluted tubules and collecting tubules show degeneration and the ...
M.K. EL-NAFFAR +4 more
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Current Research in PhysiologyKidney Injury Molecule-1 (KIM-1) has emerged as a significant biomarker and mechanistic player in kidney pathology, particularly in acute kidney injury (AKI).
Ping L. Zhang, Ming-Lin Liu
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Determinants of the effect of furosemide on the proximal tubule
Kidney International, 1972 Determinants of the effect of furosemide on the proximal tubule.The recollection renal micropuncture technique was used to assess fractional and, on occasion, absolute volume reabsorption in the dog late proximal tubule before and during a furosemide diuresis in which urine losses were or were not replaced.Similar observations were made before and ...
Burke, Thomas J. +2 more
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Renal fibrosis: Primacy of the proximal tubule [PDF]
Matrix Biology, 2018 Tubulointerstitial fibrosis (TIF) is the hallmark of chronic kidney disease and best predictor of renal survival. Many different cell types contribute to TIF progression including tubular epithelial cells, myofibroblasts, endothelia, and inflammatory cells.
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PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubulesResearch in context
EBioMedicine, 2018 Background: The renal tubules, which have distant metabolic features and functions in different segments, reabsorb >99% of approximately 180 l of water and 25,000 mmol of Na + daily.
Zhongshi Lyu +9 more
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Guangxi Yike Daxue xuebaoHypertension is a multifactorial disorder involving genetic susceptibility, neuroendocrine dysregulation, cardiovascular and kidney dysfunction, and dietary factors.
LI Xiaochun +5 more
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Case Reports in Transplantation, 2015 Sickle cell nephropathy (SCN) is associated with iron/heme deposition in proximal renal tubules and related acute tubular injury (ATI). Here we report the utility of iron staining in differentiating causes of renal allograft dysfunction in patients with ...
Yingchun Wang +4 more
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Comparative Physiology of the Renal Proximal Tubule
Kidney and Blood Pressure Research, 1985 The comparative physiology of the renal proximal tubule (PT) is reviewed in the context of vertebrate evolution and vertebrate strategies of salt and water balance. Though extrarenal machanisms of salt and water balance contribute importantly to extracellular fluid (ECF) homeostasis in the lower vertebrates, the kidney acquires these functions with ...
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