Results 31 to 40 of about 54,422 (163)

Mitochondrial and metabolic dysfunction in renal convoluted tubules of obese mice: protective role of melatonin. [PDF]

PLoS ONE, 2014
Obesity is a common and complex health problem, which impacts crucial organs; it is also considered an independent risk factor for chronic kidney disease.
Alessandra Stacchiotti, Gaia Favero, Lorena Giugno, Antonio Lavazza, Russel J Reiter, Luigi Fabrizio Rodella, Rita Rezzani   +6 more
doaj   +1 more source

Spatio-temporal expression of membrane transporters, Megalin and Cubilin, in renal development of C57BL/6 mice

陆军军医大学学报
Objective To observe the distribution of membrane transporters, Megalin and Cubilin, in the renal development of mice, and to reveal the temporal and spatial rules of their functional differentiation during renal development.
LUO Mei, ZHAI Xiaoyue, MA Yunsheng
doaj   +1 more source

Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation

Scientific Reports
Acute kidney injury (AKI) can progress to chronic kidney disease (CKD), via a mechanism that is still largely unknown. We previously reported that glucosylceramide (GlcCer) acts as a damage-associated molecular pattern (DAMP) during AKI.
Akinori Osada, Miyako Tanaka, Yuki Sugiura, Xunmei Yuan, Shinji Yamashita, Kozue Ochi, Hiro Kohda, Ayaka Ito, Shiori Go, Tetsuya Okajima, Kenji Kadomatsu, Motoko Yanagita, Kazuhiro Furuhashi, Shoichi Maruyama, Takayoshi Suganami   +14 more
doaj   +1 more source

Morfometría de cortes histológicos de los túbulos renales normales en una muestra de humanos adultos

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: los túbulos renales normales se han descrito por morfometría, lo que permite “reconstruir” en tercera dimensión la forma y el tamaño del espécimen estudiado.Objetivo: caracterizar la magnitud de los túbulos renales normales en humanos adultos,
Miosotis de Lourdes Fernández Lastre, Iraldo Mederos Pérez, Yardelys Rego Juhe, Sandor Varela Iraola, Tamara Caraballoso Recio   +4 more
doaj  

Fine Structure of the Trunk Kidney and Distribution of Its Secreted Exosomes in the Adult Zebrafish

Shiyan dongwu yu bijiao yixue, 2023
Objective To observe the fine structure of the trunk kidney in zebrafish, and to identify its secreted exosomes.Methods The microstructure and ultrastructure of the trunk kidney in zebrafish were observed by light microscopy and electron microscopy, and ...
LIN Jinxing, WANG Xindong, BAI Xuebing, FENG Liping, XIE Shuwu, CHEN Qiusheng   +5 more
doaj   +1 more source

The kidney of the Nodularia freshwater mussel has a larger filtration-size and counter-current system with improved water excretion compared with the seawater mussel Mytilus

Biology Open, 2021
Histological studies and magnetic resonance imaging were employed to analyze the kidney structure and function of the freshwater mussel, Nodularia douglasiae. The Nodularia kidney consists of proximal, intermediate and distal tubules.
Eriko Seo, Hidefumi Wakashin, Yoshiteru Seo   +2 more
doaj   +1 more source

User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium

APL Bioengineering, 2023
Drug-induced nephrotoxicity is a leading cause of drug attrition, partly due to the limited relevance of pre-clinical models of the proximal tubule. Culturing proximal tubule epithelial cells (PTECs) under fluid flow to mimic physiological shear stress ...
Natalie N. Khalil, Andrew P. Petersen, Cheng J. Song, Yibu Chen, Kaelyn Takamoto, Austin C. Kellogg, Elaine Zhelan Chen, Andrew P. McMahon, Megan L. McCain   +8 more
doaj   +1 more source

Bioactivity of Ribes nigrum L. Juice and Waste Extracts: Chemical Composition, Antioxidant, and Antiproliferative Properties

Plants
This study aimed to assess phytochemical profiles and antioxidant activities of lyophilized black currant fruit juice (BCLJ) and its corresponding waste extract (BCLW) from the Čačanska crna variety, and to evaluate their antiproliferative properties ...
Milica Trajković, Bojana Miladinović, Dragan Mihailović, Stevo Najman, Milica Milutinović, Milica Randjelović, Miloš Jovanović, Nemanja Kitić, Katarina Šavikin, Dušanka Kitić   +9 more
doaj   +1 more source

Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity

Journal of Transplantation, 2015
Tacrolimus (FK506) is one of the principal immunosuppressive agents used after solid organ transplantations to prevent allograft rejection. Chronic renal injury induced by tacrolimus is characterized by linear fibrosis in the medullary rays; however, the
Diane Cosner, Xu Zeng, Ping L. Zhang
doaj   +1 more source

Immunohistochemical localization of catalase in geese (anser anser) kidney [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The aim of this study is to observe the histologic structure of kidney tissue of geese and to determine the immunohistochemical localization of catalase in it. Six female geese were used in our study.
Serap KORAL TAŞÇI, Nurhayat GÜLMEZ, Şahin ASLAN, Turgay DEPREM, Seyit Ali BİNGÖL   +4 more
doaj   +1 more source