Results 51 to 60 of about 99,225 (351)
Advanced Healthcare Materials, EarlyView.Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao +20 more
wiley +1 more source
Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation
Scientific ReportsAcute kidney injury (AKI) can progress to chronic kidney disease (CKD), via a mechanism that is still largely unknown. We previously reported that glucosylceramide (GlcCer) acts as a damage-associated molecular pattern (DAMP) during AKI.
Akinori Osada +14 more
doaj +1 more source
陆军军医大学学报Objective To observe the distribution of membrane transporters, Megalin and Cubilin, in the renal development of mice, and to reveal the temporal and spatial rules of their functional differentiation during renal development.
LUO Mei, ZHAI Xiaoyue, MA Yunsheng
doaj +1 more source
Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]
, 2009 Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Jones, E. A., Naylor, Richard William
core +1 more source
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Advanced Healthcare Materials, EarlyView.Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source
APL Bioengineering, 2023 Drug-induced nephrotoxicity is a leading cause of drug attrition, partly due to the limited relevance of pre-clinical models of the proximal tubule. Culturing proximal tubule epithelial cells (PTECs) under fluid flow to mimic physiological shear stress ...
Natalie N. Khalil +8 more
doaj +1 more source
Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling
Advanced Healthcare Materials, EarlyView.A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl +8 more
wiley +1 more source
Morfometría de cortes histológicos de los túbulos renales normales en una muestra de humanos adultos
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017 Fundamento: los túbulos renales normales se han descrito por morfometría, lo que permite “reconstruir” en tercera dimensión la forma y el tamaño del espécimen estudiado.Objetivo: caracterizar la magnitud de los túbulos renales normales en humanos adultos,
Miosotis de Lourdes Fernández Lastre +4 more
doaj
PENGARUH ASPARTAM TERHADAP KADAR KREATININ SERUM DAN STRUKTUR HISTOLOGIS REN MENCIT (Mus Musculus L.) STRAIN SWISS [PDF]
, 2007 Umi Barokah Irawati. 2006. THE EFFECT OF ASPARTAME TO THE SERUM CREATININE LEVEL AND HISTOLOGIC STRUCTURE OF KIDNEY IN MICE (Mus musculus L.) STRAIN SWISS. Departement of Biology. Faculty of Mathematics and Natural Science.
Irawati, Umi Barokah
core
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability [PDF]
, 2017 Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. Am J Physiol Renal Physiol 313: F174 –F183, 2017.
Chen, Ying +3 more
core +1 more source