Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). [PDF]
Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans.
A Ertmer +49 more
core +3 more sources
Novel Advances in Cell-Free Therapy for Premature Ovarian Failure (POF): A Comprehensive Review [PDF]
Premature ovarian failure (POF), is a condition characterized by the early decline of ovulation function. POF is a complex disorder that can be caused by various factors, and the idiopathic form represents a significant proportion of POF patients ...
Yahya Yahyavi +9 more
doaj +1 more source
Plasma rich-platelet (PRP) potentially attenuates tamoxifen spermatogenic dysfunction in rat's model: sperm quality, histomorphometric, and apoptosis assessment [PDF]
Background: Tamoxifen induces testicular atrophy and azoospermia. Conversely, platelet-rich plasma (PRP) is a distinctive analog yield enriched with cytokines and growth factors for improving tissue regeneration.
Hossein Hamali +3 more
doaj +1 more source
Effects of local administration of platelet-rich plasma and guided tissue regeneration on bone healing in early inserted dental implants - a histomorphometric analysis [PDF]
Introduction. In order to provide the most favorable conditions for bone healing following implant loading, new techniques such as the use of growth factors to directly or indirectly regulate cell and tissue growth are becoming increasingly popular ...
Duka Miloš +5 more
doaj +1 more source
HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons [PDF]
Platelet-rich plasma (PRP) containing hepatocyte growth factor (HGF) and other growth factors are widely used in orthopaedic/sports medicine to repair injured tendons.
A Mishra +61 more
core +1 more source
Platelet-rich plasma (PRP) has been a focus of researchers and clinicians for quite some time with mixed results reported. From stunning laboratory animal success to disappointing clinical studies, a clear picture has not emerged.2 Yet, the enthusiasm for cell-based therapies is understandable.
openaire +2 more sources
Osteochondral Lesion of Talus: Role of Bone Marrow Aspirate Concentrate and Microfracture—What Does the Current Literature Say? [PDF]
Osteochondral lesions (OCL) are increasingly being identified at present. These lesions include both osteochondritis dissecans (OCD) and osteochondral fractures.
Prateek Behera +2 more
doaj +1 more source
The role of PRP and adipose tissue-derived keratinocytes on burn wound healing in diabetic rats [PDF]
Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients. The aim of this study is to investigate the use of platelet rich-plasma (PRP) and/or keratinocyte-like cells (KLCs) in diabetic thermal wound rat model and ...
Navid Hosseini Mansoub +5 more
doaj +1 more source
Aims: The present study investigates the effectiveness of platelet-rich plasma (PRP) gel without adjunct to induce cartilage regeneration in large osteochondral defects in a rabbit model.
Fathia Slimi +9 more
doaj +1 more source
Purpose: To evaluate the outcomes of patients who had osteochondral lesions of the talus treated with osteochondral allograft transplants combined with platelet-rich plasma (PRP) and hyaluronic acid (HA).
George A. Rublev, M.D. +11 more
doaj +1 more source

