Results 151 to 160 of about 1,549,882 (213)

Prion seeding activity in DNA extractions: implications for laboratory biosafety. [PDF]

Prion
Gresch SC, Morrill T, Ellis-Cramer M, Arifin M, Frank LE, Bartz JC, Schwabenlander MD, Wolf TM, Mitchell GB, Guan J, Larsen PA.   +10 more
europepmc   +1 more source

Membrane-anchored PrPSc is the trigger for prion synaptotoxicity. [PDF]

PLoS Pathog
Gatdula JRP, Mercer RCC, Alepuz Guillen JA, Vultaggio JS, Harris DA.   +4 more
europepmc   +1 more source

Molecular Mechanisms and Therapeutic Potential of Degron-Mediated Proteostasis Regulation in Neurodegenerative Diseases. [PDF]

Cell Mol Neurobiol
Nishanth DS, Sinha U, Verma T, Kalidass B, Thirumuruganandham SP, Kodiveri Muthukaliannan G.   +5 more
europepmc   +1 more source

Genetic Creutzfeldt-Jakob disease linked to the E200K mutation: a large cohort study. [PDF]

Acta Neuropathol
Appleby BS, Manca M, Piazza MS, Kerr TD, Cornacchia A, Bizzi A, Kraus A, Cohen ML, Cali I.   +8 more
europepmc   +1 more source

Oligosaccharyltransferase (OST) complex inhibition effectively treats rodent and human prions. [PDF]

PLoS Pathog
Beauchemin KS, Kun J, Groveman B, Williams K, Salerno F, Francomacaro LM, Robison P, Haigh CL, Supattapone S.   +8 more
europepmc   +1 more source

Enhanced lysosomal activity prevents infection with PrP^Sc and the seeding activity of α-synuclein & tau prions. [PDF]

J Biol Chem
Mercer RCC, Le NTT, Mirza-Romero NA, Orbe IC, Flaherty E, DeFranco JP, Lavigna G, Gatdula JRP, Fraser DG, Sundaravadivelu A, Vultaggio JS, Beeler AB, Chiesa R, Telling GC, Harris DA.   +14 more
europepmc   +1 more source

Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex. [PDF]

PLoS Pathog
Sellitto S, Caredio D, Bimbati M, Mariutti G, Cerisoli M, Frick L, Bouris V, Morales COO, Vena DL, Neupane S, Baroni F, Ging K, Yin JA, De Cecco E, Armani A, Aguzzi A.   +15 more
europepmc   +1 more source

A Neuronal Cell Line Model for Studying Camel Prions. [PDF]

Pathogens
Abdulrahman B, Rahimi Aqdam S, Mosca M, Ahmed-Hassan H, Razcon-Echeagaray M, Popa L, Gilch S, Babelhadj B, Vaccari G, Schätzl HM.   +9 more
europepmc   +1 more source

Emerging risks at the vampire bat-prion interface: implications for wildlife, livestock, and public health. [PDF]

J Mammal
Frank LE, Bartz JC, Larsen PA.
europepmc   +1 more source

Formic acid treatment drastically reduces sporadic Creutzfeldt-Jakob disease and variant Creutzfeldt-Jakob disease infectivity in histological samples as tested in a high-sensitivity mouse bioassay. [PDF]

J Gen Virol
Espinosa JC, Canoyra S, Fernández-Borges N, Marín-Moreno A, Torres JM.   +4 more
europepmc   +1 more source