Results 161 to 170 of about 1,549,882 (213)

AI-designed prion-capping proteins provide evidence that prion fibril ends are replication-competent surfaces that contribute to prion seeding activity and infectivity. [PDF]

mBio
Slota JA, Kirby M, Van Den Driessche A, Kielich DMS, Lamoureux L, Beniac DR, Layne C, Poirier M, Stetefeld J, Booth SA, Bailey-Elkin BA.   +10 more
europepmc   +1 more source

Prion shedding is reduced by chronic wasting disease vaccination. [PDF]

PLoS Pathog
Ahmed-Hassan H, Abdelaziz D, Cheng YC, Low K, Phan S, Kruger B, Dalton CS, Kaczmarczyk L, Jackson WS, Gilch S, Schätzl HM.   +10 more
europepmc   +1 more source

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases. [PDF]

Acta Neuropathol
Masone A, Grasso A, Comerio L, Bruno R, Lavigna G, Vanni I, D'Agostino C, Orrù CD, Caughey B, Altmeppen HC, Castilla J, Giaccone G, Tagliavini F, Di Bari MA, Nonno R, Chiesa R.   +15 more
europepmc   +1 more source

Identification of an altered gut microbiome and the protective effect of microbiome changer in prion diseases. [PDF]

Vet Res
Kim YC, Won SY, Jeong BH.
europepmc   +1 more source

Co-presence of classical scrapie but not classical Bovine Spongiform Encephalopathy in transmissions from Dutch sheep with atypical scrapie. [PDF]

J Gen Virol
van Keulen LJ, Dolstra CH, Bossers-de Vries R, Bossers A.   +3 more
europepmc   +1 more source

Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties. [PDF]

Acta Neuropathol Commun
Lorenzo NL, Eraña H, Vidal E, Charco JM, Parga L, Díaz-Domínguez CM, Veiga S, Bravo S, Giler S, Geijo M, Requena JR, Castilla J.   +11 more
europepmc   +1 more source

Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets. [PDF]

Microbiol Mol Biol Rev
Caughey B, Artikis E, Shoup D, Orrú CD, Alam P, Parveen S, King S, Soukup J, Hughson AG, Priola SA.   +9 more
europepmc   +1 more source

Pathological and Functional Brain Amyloids: A New Concept Explaining the Differences. [PDF]

Int J Mol Sci
Galkin AP, Mitkevich VA, Makarov AA, Valina AA, Sysoev EI.   +4 more
europepmc   +1 more source

Methamphetamine increases Prion Protein and induces dopamine-dependent expression of protease resistant PrPsc

Archives Italiennes de Biologie, 2017
The cellular prion protein (PrPc) is physiologically expressed within selective brain areas of mammals. Alterations in the secondary structure of this protein lead to scrapie-like prion protein (PrPsc), which precipitates in the cell. PrPsc has been detected in infectious, inherited or sporadic neurodegenerative disorders.
FERRUCCI, MICHELA, RYSKALIN, LARISA, BIAGIONI, FRANCESCA, Gambardella, S, Busceti, Cl, FALLENI, ALESSANDRA, LAZZERI, GLORIA, FORNAI, FRANCESCO   +7 more
openaire   +4 more sources