A neural stem cell-derived 3D spheroid model that recapitulates prion infection and pathology. [PDF]
Park HJ, Kim H, Byun S, Ryou C.
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Cellular prion protein and its derived peptides: multifaceted roles in neurodegenerative diseases and potential as biomarkers. [PDF]
Mari E +9 more
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Therapeutic strategies in prion disease: current evidence, translational challenges, and emerging directions. [PDF]
Zhu Y, Bradford BM, Mabbott NA.
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Epigenetic changes associated with the progression of prion disease in Syrian hamsters (<i>Mesocricetus auratus</i>). [PDF]
Frank LE +5 more
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Preclinical serum alterations and tissue changes in protein and gene expression of early cerebrospinal fluid-validated biomarkers in scrapie. [PDF]
Pérez-Lázaro S +4 more
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The octapeptide repeats of prion protein play critical roles in the pathogenesis of prion diseases. [PDF]
Zhang X +11 more
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PrP<sup>C</sup>-facilitated cell signaling activates phospholipase Cɣ1 and triggers an Arc/Arg3.1 response in mouse and iPSC-derived human neurons. [PDF]
Ojeda-Juarez D +10 more
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Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells. [PDF]
Rayner MLD +13 more
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Prion Diseases-When Proteins Turn Lethal: Creutzfeldt-Jakob Disease (CJD) and the Quest for Classification, Diagnosis, Therapeutic Approaches, and Emerging Research. [PDF]
Ramesh TS +3 more
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Comparison of acetone and sodium phosphotungstic acid precipitation for sample enrichment prior to RT-QuIC for the detection of prion disease. [PDF]
Nicholson EM, Veneziano SE.
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