Results 121 to 130 of about 1,549,882 (213)

Report of the Working Group `Overall Blood Supply Strategy with Regard to Variant Creutzfeldt-Jakob Disease (vCJD)' [PDF]

, 2009
von Koenig, Carl-Heinz Wirsing, Seitz, Rainer, Schlenkrich, Uwe, Gröner, Albrecht, Zerr, Inga, von Dewitz, Christian, Kretzschmar, Hans A., Bluemel, Johannes, Groener, Albrecht, Beekes, Michael, Strobel, Johanna, Heiden, Margarethe, Nuebling, Micha, Willkommen, Hannelore, Dewitz, Christian von, Blümel, Johannes, Burger, Reinhard, Kretzschmar, Hans, Wirsing von König, Carl-Heinz, Schottstedt, Volkmar   +19 more
core   +1 more source

Enfermedad de creutzfeldt-jakob en el Perú: reporte de once casos

Revista Peruana de Medicina Experimental y Salud Pública
La enfermedad de Creutzfeldt-Jakob (ECJ) es una enfermedad neurológica fatal producida por la isoforma patológica de la proteína priónica humana.
Luis Torres-Ramírez, Jorge Ramírez-Quiñones, Carlos Cosentino-Esquerre, Miriam Vélez-Rojas, Martha Flores-Mendoza, Diana Rivas-Franchini, Rafael Suarez-Reyes, Yesenia Núñez-Coronado   +7 more
doaj   +2 more sources

An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast Ure2p prion-inducing domain.

Acta biochimica et biophysica Sinica, 2004
Production of the pathogenic prion isoform PrPsc-like molecules is thought to be useful for understanding the mysterious mechanism of conformational conversion process of prion diseases and proving the "protein-only" hypothesis. In this report, an engineered PrPsc-like conformation was produced from a chimera of mammalian bovine prion protein (bPrP ...
Shao-Man, Yin, Man-Sun, Sy, Tien, Po
openaire   +1 more source

Detection and discrimination of PrPSc by multi-spectral ultraviolet fluorescence

, 1998
Prion diseases are progressive degenerative disorders of the central nervous system. The transmissibility and fatal nature of these diseases necessitate their rapid and accurate diagnosis.
TISONE, GIUSEPPE, Wagner, JS, Gray, PC, Rubenstein, R, Wehlburg, CM   +4 more
core   +1 more source

The axonal transport velocity of prions is independent of prion formation. [PDF]

PLoS Pathog
Koshy SM, Hrdlicka J, Nichols MG, Stender AS, Taylor JH, Castilla J, Bartz JC.   +6 more
europepmc   +1 more source

Generation of Infectious Prions Amenable to Site-Specific Click Chemistry. [PDF]

ACS Chem Biol
Campbell RG, Iseler JN, Schwind AM, Supattapone S.   +3 more
europepmc   +1 more source

Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs. [PDF]

PLoS Pathog
Le NTT, Mercer RCC, Fang C, Sundaravadivelu A, Labadorf AT, Lin W, Kwan J, Blum B, Emili A, Harris DA.   +9 more
europepmc   +1 more source

A self-complementary recombinant adeno-associated virus vector coding for an anchorless prion protein carrying the G127V mutation extends survival in a rodent prion disease model. [PDF]

PLoS Pathog
Zerbes T, Verkuyl C, Zhang C, Grunnesjoe S, Eid S, Arshad H, Zhao W, Nasser Z, O'Shea T, Bel A, Lamoureux L, Frost KL, Myskiw J, Li LY, Stuart E, Wille H, Booth S, Watts JC, Schmitt-Ulms G.   +18 more
europepmc   +1 more source

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy. [PDF]

Neurobiol Dis
Gatdula JRP, Mirza-Romero NA, Orbe IC, Saunders LM, Tolton SG, Vultaggio JS, Mercer RCC, Bartz JC, Telling GC, Eraña H, Castilla J, Harris DA.   +11 more
europepmc   +1 more source

The protein disulfide isomerase P4HB/PDIA1 modulates cellular and misfolded forms of the prion protein. [PDF]

PLoS Pathog
Amano G, Arshad H, Patel Z, Schmitt-Ulms G, Watts JC.   +4 more
europepmc   +1 more source