Results 151 to 160 of about 10,101 (182)

Presence of PRRSV in wild boar in Italy

Veterinary Record, 2006
SIR, – The wild boar ( Sus scrofa ) population in Italy has increased during the past 30 years, as it has in other European countries, such as Spain, France, Germany and Croatia. Direct or indirect contact between wild boar and domestic pigs ( Sus scrofa domesticus ) may occur occasionally ...
Paolo, Bonilauri, Giuseppe, Merialdi, Michele, Dottori, Ilaria, Barbieri   +3 more
openaire   +2 more sources

Broad neutralization activity against both PRRSV-1 and PRRSV-2 and enhancement of cell mediated immunity against PRRSV by a novel IgM monoclonal antibody

Antiviral Research, 2020
Porcine reproductive and respiratory syndrome (PRRS) is the most economically important infectious disease affecting the global swine industry, especially since vaccination has had limited impact on PRRSV prevention and control. In this study, the monoclonal antibody PR5nf1 (Mab-PR5nf1, IgM isotype) was shown to react with heterogeneous PRRSV isolates ...
Chunyan, Wu, Guoqian, Gu, Tianshu, Zhai, Yajing, Wang, Yongling, Yang, Yafei, Li, Xu, Zheng, Qin, Zhao, En-Min, Zhou, Yuchen, Nan   +9 more
openaire   +2 more sources

PRRSV receptors and their roles in virus infection

Archives of Microbiology, 2015
Porcine reproductive and respiratory syndrome virus (PRRSV) has a restricted cell tropism and prefers to invade well-differentiated cells of the monocyte/macrophage lineage, such as pulmonary alveolar macrophages and African green monkey kidney cell line MA-104 and its derivatives, such as Marc-145, Vero and CL-2621.
Chongxu, Shi, Yali, Liu, Yaozhong, Ding, Yongguang, Zhang, Jie, Zhang   +4 more
openaire   +2 more sources

Mechanistic Insights into PRRSV Inhibition through CD163–SRCR5 Blockade by PRRSV/CD163-IN-1

The Journal of Physical Chemistry Letters
Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe economic losses in the swine industry by targeting pulmonary alveolar macrophages via the CD163 receptor, particularly its SRCR5 domain. However, the molecular details of small-molecule inhibition at this interface remain unclear.
Prawit Thitayanuwat, Kowit Hengphasatporn, Surang Chankhamhaengdecha, Yasuteru Shigeta   +3 more
openaire   +2 more sources

Packaged Heteroclite Subgenomic RNAs of PRRSV

2001
Porcine reproductive and respiratory syndrome virus (PRRSV) is a member of the Arteriviridae family of the Nidovirales (Meulenberg et al, 1993b; Nelsen et al., 1999). While the complete genomes of three PRRSV strains are known (Allende et al., 1999; Meulenberg et al., 1993; Nelsen et al., 1999), main questions remains to be elucidated concerning viral ...
S, Yuan, M P, Murtaugh, K S, Faaberg
openaire   +2 more sources

Different expression patterns of PRRSV mediator genes in the lung tissues of PRRSV resistant and susceptible pigs

Developmental & Comparative Immunology, 2013
Porcine reproductive and respiratory syndrome (PRRS) has caused severe economic loss in most swine-producing countries. The resistance to PRRS virus (PRRSV) infection varies among pig breeds and lines. In this study, we found that the Chinese Dapulian pigs (DPL) were more resistant to PRRSV than commercial Duroc×Landrace×Yorkshire (DLY) crossbred pigs ...
Chenglan, Jiang, Feng, Xing, Jinyi, Xing, Yunliang, Jiang, Enmin, Zhou   +4 more
openaire   +2 more sources

Efficacy of Type 2 PRRSV vaccine against Chinese and Vietnamese HP-PRRSV challenge in pigs

Vaccine, 2014
Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant reproductive losses in the sow herd and respiratory disease in growing pigs. The virus belongs to the family Arteriviridae and there are two major genotypes. Type 1 is represented by Lelystad virus, the European prototype virus, and Type 2 is represented by the North ...
Kelly M, Lager, Sarah N, Schlink, Susan L, Brockmeier, Laura C, Miller, Jamie N, Henningson, Matthew A, Kappes, Marcus E, Kehrli, Crystal L, Loving, Baoquing, Guo, Sabrina L, Swenson, Han-Chun, Yang, Kay S, Faaberg   +11 more
openaire   +2 more sources

Development of blocking ELISA for detection anti-PRRSV antibodies and serological investigation of PRRSV in China

International Journal of Biological Macromolecules
Porcine reproductive and respiratory syndrome virus (PRRSV) demonstrates a significantly high prevalence among swine populations. Monoclonal antibodies (mAbs) with high affinity for conserved epitopes of PRRSV can facilitate the development of a broad-spectrum detection method for this virus.
Shujie, Wang, Tianfeng, Chen, Yong-Bo, Yang, Hongfeng, Wang, Mingxia, Sun, Kexin, Gao, Ziyi, Wei, Yuanzhe, Bai, Yan-Dong, Tang, Xuehui, Cai, Tongqing, An   +10 more
openaire   +2 more sources

Syndecan-4, a PRRSV attachment factor, mediates PRRSV entry through its interaction with EGFR

Biochemical and Biophysical Research Communications, 2016
The causative agent of porcine reproductive and respiratory syndrome is the PRRS virus (PRRSV), an enveloped, single-stranded and positive-sense RNA virus. The host factors and mechanisms that are involved in PRRSV entry are still largely unknown.
Rui, Wang, Xin, Wang, Bo, Ni, Chang-Chao, Huan, Jia-Qiang, Wu, Li-Bin, Wen, Ying, Liao, Guang-Zhi, Tong, Chan, Ding, Hong-Jie, Fan, Xiang, Mao   +10 more
openaire   +2 more sources

The mRNA vaccine expressing fused structural protein of PRRSV protects piglets against PRRSV challenge

Veterinary Microbiology
The swine industry experiences substantial economic losses annually due to the porcine reproductive and respiratory syndrome virus (PRRSV). The limited protective efficacy of existing commercial vaccines against epidemic PRRSV underscores the urgent need for innovative solutions.
Chunxiao, Mou, Xing, Zhao, Chen, Zhuo, Qing, He, Mengwei, Xu, Kaichuang, Shi, Tiyun, Han, Shi, Xu, Zhenhai, Chen   +8 more
openaire   +2 more sources