Results 171 to 180 of about 119,934 (290)

Six Injections of Modified Adjuvanted PQ Grass Is Effective and Well‐Tolerated in a Pivotal Phase III Trial

open access: yesAllergy, EarlyView.
A pivotal Phase III DBPC adaptive trial was conducted with PQ Grass 27600 SU. The primary endpoint EAACI‐CSMS0–6 demonstrated a highly significant, clinically meaningful improvement for PQ Grass of −0.27 points (95% CI: −0.42 to −0.12), corresponding to a relative difference of −20.3% (p = 0.0005) over placebo. Highly consistent secondary endpoints and
Stefan Zielen   +100 more
wiley   +1 more source

Skin disease in captive bats: results of an online survey of zoos and rehabilitators in Europe, North America and Australasia [PDF]

open access: yes, 2017
Bello-Gutiérrez   +15 more
core   +1 more source

Oral Immunotherapy in Peanut‐Allergic Adults Using Real‐World Materials

open access: yesAllergy, EarlyView.
In 21 adults initiated on peanut oral immunotherapy (OIT), 67% tolerated at least 1000 mg on exit DBPCFC. Decreases in SPT size and increases in peanut‐ and Ara h 2‐specific IgG occurred in OIT participants but not in mechanistic controls (n = 9). Improvements were seen in FAQLQ‐AF and food neophobia scores.
Hannah Hunter   +10 more
wiley   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

open access: yesAllergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy   +17 more
wiley   +1 more source

Minimal Clinically Important Difference in Chronic Pruritus Appears to be Dependent on Baseline Itch Severity

open access: yesActa Dermato-Venereologica, 2019
Claudia Riepe   +5 more
doaj   +1 more source

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