Preparation of PLGA (poly lactic-co-glycolic acid) nanoparticles Containing Pseudomonas aeruginosa Alginate, LPS and Exotoxin A as a Nano-vaccine [PDF]
Biological Journal of Microorganism, 2018 Introduction: Pseudomonas aeruginosa is a particular importance due to the numerous factors of pathogenicity and the prevalence of multi-resistance strains throughout the world.
Leila Safari zanjani +4 more
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Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]
, 2015 In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen +6 more
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Dissecting HOCl Action in Chronic Wound Biofilms: Proteomic Insights From a Host-Relevant Model of Pseudomonas aeruginosa. [PDF]
MicrobiologyopenImpact statement: We tested a gel containing a pure, stable form of hypochlorous acid (HOCl) against P. aeruginosa. To ensure our results reflect the true effects of HOCl we used a host‐relevant biofilm model. The HOCl gel disrupted bacterial metabolism, impacted proteins associated with virulence, and changed the abundance antibiotic resistance ...
Robins LI +4 more
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Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates [PDF]
, 2017 Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and ...
Deris, Fatemeh. +4 more
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Demonstration of cell envelope-bound exotoxin A in Pseudomonas aeruginosa [PDF]
Infection and Immunity, 1980 The quantity of membrane-bound and extracellular exotoxin A in four strains of Pseudomonas aeruginosa was investigated. In strain PA-103, which is the prototype strain used for toxin production, all of the toxin was released into the growth medium and little toxin remained with the cell envelope. In a virulent strain from a clinical source, strain 119,
P B, Fernandes, K R, Cundy
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Multifaceted Interplay between Hfq and the Small RNA GssA in Pseudomonas aeruginosa
mBio, 2023 Behind the pathogenic lifestyle of Pseudomonas aeruginosa exists a complex regulatory network of intertwined switches at both the transcriptional and posttranscriptional levels.
Silvia Santoro +5 more
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Early detection of – comparison of conventional versus molecular (PCR) detection directly from adult patients with cystic fibrosis (CF) [PDF]
, 2004 Background Pseudomonas aeruginosa (PA) is the most important bacterial pathogen in patients with cystic fibrosis (CF) patients. Currently, routine bacteriological culture on selective/non- selective culture media is the cornerstone of microbiological ...
Jiru Xu +4 more
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Alteration of murine immune response by Pseudomonas aeruginosa exotoxin A [PDF]
Infection and Immunity, 1984 Pseudomonas exotoxin A has been implicated as a possible virulence factor in Pseudomonas infections. This toxin has a direct cytotoxic effect on a number of cell types, including macrophages and their precursors, and therefore may affect other cells of the immune system.
P S, Holt, M L, Misfeldt
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Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells. [PDF]
, 2015 Pseudomonas aeruginosa infection can be disastrous in chronic lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. Its toxic effects are largely mediated by secreted virulence factors including pyocyanin, elastase and alkaline
Clarke, Hanna J +7 more
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Exotoxin A Pseudomonas aeruginosa influence on working efficiency of white rats [PDF]
Саратовский научно-медицинский журнал, 2017 Objective: to study exotoxin A Pseudomonas aeruginosa influence on physical and mental efficiency of white rats. Material and Methods. The experiments were carried out on white rats following intraperitoneal injections of exotoxin A Pseudomonas of ...
Morrison V.V. +3 more
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