Pseudomonas aeruginosa Alters Critical Lung Epithelial Cell Functions through Activation of ADAM17
Cells, 2022 Severe epithelial dysfunction is one major hallmark throughout the pathophysiological progress of bacterial pneumonia. Junctional and cellular adhesion molecules (e.g., JAMA-A, ICAM-1), cytokines (e.g., TNFα), and growth factors (e.g., TGFα), controlling
Ahmad Aljohmani +2 more
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Respirology Case Reports, Volume 14, Issue 1, January 2026.Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Shun Endo +4 more
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Инфекция и иммунитет, 2021 The aim of the study was to obtain and characterize a recombinant vaccine for the immunoprophylaxis of infections caused by Pseudomonas aeruginosa. A set of two highly immunogenic P. aeruginosa recombinant proteins was used to create related vaccine. The
A. A. Kaloshin +3 more
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Analysis of transcription of the exotoxin A gene of Pseudomonas aeruginosa [PDF]
Journal of Bacteriology, 1986 Analysis of RNA isolated from Pseudomonas aeruginosa PA103 and PAKS grown under Fe2+-limiting (0.08 microgram/ml) and Fe2+-sufficient (10 micrograms/ml) conditions demonstrated that exotoxin A (ETA) expression is regulated by Fe2+ at the level of transcription.
C C, Grant, M L, Vasil
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Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana
MicrobiologyOpen, Volume 14, Issue 6, December 2025.This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Bismark Donkor +6 more
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Pseudomonas infection: exotoxin A effect [PDF]
Саратовский научно-медицинский журнал, 2014 The aim of the article is to present the data analysis of the Russian and foreign literature concerning the current situation of the problem, the frequency and mechanisms of pseudomonas infection development and factors of patho-genicity of Pseudomonas ...
Morrison A.V. +2 more
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Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes.
PLoS Biology, 2020 Pathogens such as Pseudomonas aeruginosa advantageously modify animal host physiology, for example, by inhibiting host protein synthesis. Translational inhibition of insects and mammalian hosts by P. aeruginosa utilizes the well-known exotoxin A effector.
Alejandro Vasquez-Rifo +2 more
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Pseudomonas aeruginosa: Prevalence of Pathogenic Genes, OprL and ToxA in Human and Veterinary Clinical Samples in Ardabil, Iran, 2020 [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: An opportunistic pathogen Pseudomonas aeruginosa can cause frequent hospital-acquired infections as well as one microorganism in the food spoilage. Also, the emergence of multidrug-resistant P.
Ciamak Ghazaei
doaj
Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model. [PDF]
PLoS ONE, 2017 The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling virulence factors and biofilm formation in Pseudomonas aeruginosa.
Jing Luo +10 more
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Ecthyma gangrenosum caused by Pseudomonas aeruginosa in a patient with astrocytoma treated with chemotherapy [PDF]
, 2010 Ecthyma gangrenosum, presenting as embolic lesions caused by Pseudomonas aeruginosa infection, has distinct pathognomonic features and a high mortality rate in patients with bacteremia, but when recognized early is easily treated.
Jonge, M.J.A. (Maja) de +3 more
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