Results 81 to 90 of about 9,621 (218)
APseudomonas aeruginosaalginate-exotoxin A conjugate that elicits anti-alginate and exotoxin A-neutralizing antibodies [PDF]
FEMS Microbiology Letters, 1991 Pseudomonas aeruginosa alginate was covalently coupled to exotoxin A by reductive amination using adipic acid dihydrazide as spacer. The conjugate was composed of 25% alginate and 75% exotoxin A and possessed an average molecular mass higher than 700 kDa as determined by polyacrylamide gel electrophoresis.
D, Coin +3 more
openaire +2 more sources
Food Science &Nutrition, Volume 13, Issue 9, September 2025.This article discusses the pathophysiology of wound infection, beginning with the classification of wounds as acute and chronic wounds, and emphasizes how compromised epithelial barriers and chronic inflammation provide a niche for microbial colonization.
Chaoming Chen +4 more
wiley +1 more source
Cloning and expression of the immunogenic moiety of Pseudomonas aeruginosa exotoxin A
Biological Journal of Microorganism, 2013 Introduction: Pseudomonas aeruginosa, as an opportunistic microorganism, is a major cause of nosocomial infections worldwide. Exotoxin A (ETA) is an extracellular enzyme that is produced by most clinical strains of P. aeruginosa.
Sahar Nouri Gharajelar * +2 more
doaj
Isolation Virulence genes ETA, OPrL, gyrB in Pseudomonas aeruginosa clinical samples from hospitals in Kerman by Multiplex-PCR [PDF]
, 2016 زمینه و هدف: سودوموناس آئروژینوزا یک پاتوژن فرصت طلب و عامل عفونت های بیمارستانی و مرگ و میر به خصوص در بیماران با ضعف سیستم ایمنی می باشد و مقاومت ذاتی به مواد ضد میکروبی منجر به مشکلاتی در درمان عفونت های آن می شود.
Amini, K., Kamali, A.
core +1 more source
Chimerolectins: Classification, structural architecture, and functional perspectives
Protein Science, Volume 34, Issue 9, September 2025.Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior +2 more
wiley +1 more source
PLoS ONE, 2014 Infections with Pseudomonas aeruginosa have been a long-standing challenge for clinical therapy because of complex pathogenesis and resistance to antibiotics, thus attaching importance to explore effective vaccines for prevention and treatment.
Mingzi Jiang, Jing Yao, Ganzhu Feng
doaj +1 more source
Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application
Exploration, Volume 5, Issue 4, August 2025.This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang +4 more
wiley +1 more source
Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. [PDF]
, 2017 The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused on transcription induced by defined immunostimulatory ...
Barry, Kevin C +2 more
core +3 more sources
Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies
Microbial Biotechnology, Volume 18, Issue 8, August 2025.Polymicrobial biofilms: interkingdom interactions, resistance and therapeutic stratergies. This review highlights the heightened drug resistance and complexity of polymicrobial biofilms, emphasising their persistence over mono‐species counterparts. It explores microbial interactions, resistance mechanisms and emerging strategies, including metabolite ...
Paramasivam Nithyanand +3 more
wiley +1 more source
Vox Sanguinis, Volume 120, Issue 8, Page 846-857, August 2025.Abstract Background and Objectives High‐income countries have successfully enhanced platelet component (PC) safety with the implementation of mitigation strategies including donor screening, skin disinfection, first aliquot diversion and PC bacterial screening or treatment with pathogen reduction technologies (PRT).
Michel‐Andrés García‐Otálora +8 more
wiley +1 more source