Results 111 to 120 of about 3,613,662 (378)
Clinical Infectious Diseases, 2015 BACKGROUND The type III secretion system (TTSS) is a major virulence determinant of Pseudomonas aeruginosa. The objective of this study was to determine whether the TTSS genotype is a useful prognostic marker of P. aeruginosa bacteremia mortality.
C. Peña +15 more
semanticscholar +1 more source
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Advanced Science, EarlyView.The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia +12 more
wiley +1 more source
Medical Laboratory Journal, 2013 : Background and Objective: A wide variety of opportunistic pathogens has been detected in hospital surfaces. Among these , Pseudomonas species are one of the leading causes of nosocomial infections, frequently found in hospital environments. The purpose
SZ Azimi, M Ghane, Z Heshmatipour
doaj
The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]
, 2016 Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie +2 more
core +2 more sources
Clinical Infectious Diseases, 2020 BACKGROUND Antimicrobial-resistant infections are commonly encountered in US hospitals and result in significant morbidity and mortality. This guidance document provides recommendations for the treatment of infections caused by extended-spectrum β ...
P. Tamma +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang +6 more
wiley +1 more source
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]
, 2017 The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core +1 more source
Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections.
American Journal of Respiratory and Critical Care Medicine, 2015 RATIONALE Pseudomonas aeruginosa, the predominant cause of chronic airway infections of patients with cystic fibrosis, exhibits extensive phenotypic diversity among isolates within and between sputum samples, but little is known about the underlying ...
David Williams +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study developes a universal colorimetric ICA platform that integrates broad‐spectrum recognition by 4‐mercaptophenylboronic acid with dual signal enhancement—both colorimetric and catalytic—mediated by a biomimetic magnetic nanozyme. This platform, for the first time, enables simple, convenient, ultrasensitive, and simultaneous screening of ...
Qing Yu +7 more
wiley +1 more source
Phage therapy : its uses and flaws pertaining to pseudomonas aeruginosa infections [PDF]
, 2020 As cases of antibiotic resistant bacteria increase, possible alternatives to antibiotics have often been sought. One alternative discussed in literature is phage therapy.
Vella, Miguel
core