Results 161 to 170 of about 3,746,898 (399)

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki   +9 more
wiley   +1 more source

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

open access: yesAngewandte Chemie, EarlyView.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler   +4 more
wiley   +2 more sources

Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial demonstrated that a 4‐day regimen of sulbactam/ampicillin significantly reduced the incidence of perineal wound infection (PWI) following abdominoperineal resection compared to a 1‐day cefmetazole regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Akitoshi Nankaku   +12 more
wiley   +1 more source

Patient‐Specific Coculture of S. aureus and P. aeruginosa Enhances Epithelial Barrier Disruption and Virulence in CRS

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease that is associated with polymicrobial infections, often involving S. aureus and P. aeruginosa. It is unclear whether the polymicrobial context plays a role in exacerbating epithelial damage, inflammation, and resistance to therapy. Methods S. aureus and P. aeruginosa (n =
Xiaohan Sun MMed   +6 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Role of Class I, II and III Integrons in Multidrug Resistance in Pseudomonas aeruginosa Isolated from Nosocomial Hospital

open access: yesInternational Archives of Health Sciences, 2016
Aims: The increasing usage of antibiotics can cause resistance to the treatment of infections, which can caused by bacteria, e.g. Pseudomonas aeruginosa. The aim of this study was to trace the class I, II and III integrons in isolates of P. aeruginosa of
Nourbakhsh F.* PhD,, Momtaz H. PhD
doaj  

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh   +5 more
wiley   +1 more source

Pseudomonas infections among hospitalized adults in Latin America: a systematic review and meta-analysis. [PDF]

open access: yesBMC Infect Dis, 2020
Ponce de Leon A   +6 more
europepmc   +1 more source

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