Antimicrobial Cyclic Peptidomimetics
Macromolecular Rapid Communications, EarlyView.Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
Bacterial, Antimicrobial, and Clinical Profile of Multidrug-Resistant Gram-Negative Bacilli Isolates From Intensive Care Unit Patients. [PDF]
CureusChavan VG, Pawar S, Patil S.
europepmc +1 more source
Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm
Macromolecular Rapid Communications, EarlyView.Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz +4 more
wiley +1 more source
Macromolecular Symposia, EarlyView.ABSTRACT In this study, undoped and zinc‐doped hydroxyapatite (xZn = 0; 0.4; H‐LF and 4ZH‐LF) were synthesized by an adapted method (and dried by lyophilization) and characterized through a series of analytical techniques in order to evaluate their stability, morphological, and biological properties.
Liliana Ghegoiu +11 more
wiley +1 more source
Clinical characteristics and prognosis of peritoneal dialysis-associated peritonitis caused by non-fermenting Gram-negative bacteria: a single-center retrospective analysis. [PDF]
Ren FailYan H, He W, Yu D, Tong M, Ni J, Yu J.
europepmc +1 more source
Debneyol decoded: A metabolic organizer powers broad‐spectrum plant defense
New Plant Protection, EarlyView.Abstract A new Cell study by Wang et al. resolves the long‐elusive biosynthesis and regulation of debneyol, a fungicidal sesquiterpenoid phytoalexin in Solanaceae. The authors define the complete three‐step route from farnesyl pyrophosphate to debneyol and identify the small protein MCD1 as a metabolic organizer that assembles a multienzyme complex to ...
Shaojie Han
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Combination of Ceftazidime-Avibactam and Meropenem for the Treatment of Pneumonia and Bloodstream Infections Caused by Pan-Drug Resistant <i>Pseudomonas aeruginosa</i> ST244: A Case Report. [PDF]
Infect Drug ResistKang Y, Kang S, Cui J.
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Pest Management Science, EarlyView.Amino acid‐vectorized salicylic acid activates PR1/NPR1‐dependent defenses without phytotoxicity, showing an efficient strategy for controlled delivery and enhanced plant immunity. Abstract BACKGROUND Addressing global food security under rapid population growth and climate change requires sustainable strategies to protect crops from pathogens while ...
Ruth Oussou +6 more
wiley +1 more source
Recurrent/Refractory Multidrug- and Pre-Multidrug-Resistant <i>Pseudomonas aeruginosa</i> Infection Cases Maintained by Long-Term, Low-Dose Macrolide Administration. [PDF]
Clin PharmacolSeki M.
europepmc +1 more source
Pest Management Science, EarlyView.Understanding how infection timing drives disease is essential for the development of fungicide resistance management strategies. For blackleg disease of canola, all infection timings can contribute to the following generation, therefore all fungicide applications have the ability to select for resistance.
Alec J McCallum +3 more
wiley +1 more source