Results 181 to 190 of about 1,026,176 (295)

Guidelines for Immunomodulatory Assays of Food Bioactives on Drosophila melanogaster Model

open access: yesFuture Postharvest and Food, EarlyView.
Guidelines are proposed for evaluating the immunomodulatory effects of food bioactives in Drosophila melanogaster, involving treatment with bioactives, pathogen preparation, infection routes, and immune response assessment. This model highlights the conserved mechanisms of cellular and humoral immunity for studying host‐microbe interactions.
Wenqi Huang, Shiye Lin
wiley   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

open access: yesiLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

open access: yesiMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia   +11 more
wiley   +1 more source

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections. [PDF]

open access: yesSci Rep, 2016
Danis-Wlodarczyk K   +13 more
europepmc   +1 more source

Sexual dimorphism in hormone–gut microbiome associations across reproductive states in wild giant pandas

open access: yesiMetaOmics, EarlyView.
Gut microbiota–host endocrine interactions in wild mammals remain poorly understood. Giant pandas experience seasonal dietary shifts and constrained annual reproduction, offering an ideal model to investigate microbiome–endocrine coupling. We integrated fecal hormone profiling, microsatellite‐based individual identification, and gut microbiome ...
Qinlong Dai   +10 more
wiley   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

open access: yesiMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad   +8 more
wiley   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

open access: yesiMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif   +4 more
wiley   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

open access: yesiMetaOmics, EarlyView.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao   +5 more
wiley   +1 more source

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