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Genome editing of pseudorabies virus in the CRISPR/Cas9 era: a mini-review [PDF]

open access: goldFrontiers in Veterinary Science, 2023
Pseudorabies virus (PRV) is an important swine virus that has a significant impact on the global swine industry. PRV is a member of the herpesvirus family, specifically the alphaherpesvirus subfamily, and has been extensively utilized as a prototype ...
Hai-Ming Wang   +9 more
doaj   +2 more sources

Pseudorabies gD protein protects mice and piglets against lethal doses of pseudorabies virus [PDF]

open access: goldFrontiers in Microbiology, 2023
IntroductionPseudorabies (PR) is a highly contagious viral disease caused by the pseudorabies virus (PRV), which can cause disease in a wide range of domestic and wild animals.
Mengpo Zhao   +18 more
doaj   +2 more sources

Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus [PDF]

open access: goldBMC Microbiology, 2009
Background Pseudorabies virus (PRV) is an alphaherpesviruses whose native host is pig. PRV infection mainly causes signs of central nervous system disorder in young pigs, and respiratory system diseases in the adult.
Furlong RA   +7 more
doaj   +2 more sources

Antiviral activity of nitazoxanide against pseudorabies virus infection in vitro [PDF]

open access: yesFrontiers in Veterinary Science
Pseudorabies (PR), an infectious disease caused by pseudorabies virus (PRV), has been responsible for substantial economic losses within the global swine industry.
Lei Tan   +12 more
doaj   +2 more sources

Detection of Pseudorabies Virus in Hunting Dogs in Greece: The Role of Wild Boars in Virus Transmission. [PDF]

open access: goldPathogens
Papageorgiou K   +13 more
europepmc   +3 more sources

RR1 and RR2 gene deletion affects the immunogenicity of a live attenuated pseudorabies virus vaccine candidate in natural pig host [PDF]

open access: yesFrontiers of Agricultural Science and Engineering, 2016
As virulence-determining genes, RR1 and RR2 encode the small subunit and large subunit of viral ribonucleotide reductase (RR) in pseudorabies virus which have been extensively studied in mice.
Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN
doaj   +1 more source

Cross species transmission of pseudorabies virus leads to human encephalitis and visual impairment: A case report

open access: yesFrontiers in Neurology, 2022
Pseudorabies virus (PRV) is a common pig infectious disease. There have been few reports of PRV infection in humans. The patient in this article had acute onset, which was manifested by fever, epilepsy, disturbance of consciousness, and other symptoms ...
Hui Huang   +5 more
doaj   +1 more source

The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans

open access: yesViruses, 2022
Pseudorabies virus (PRV) can infect most mammals and is well known for causing substantial economic losses in the pig industry. In addition to pigs, PRV infection usually leads to severe itching, central nervous system dysfunction, and 100% mortality in ...
Qingyun Liu   +9 more
doaj   +1 more source

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