Results 111 to 120 of about 8,213 (212)

Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus. [PDF]

, 2011
BACKGROUND: Pseudorabies virus (PRV) is an alphaherpesviruses whose native host is pig. PRV infection mainly causes signs of central nervous system disorder in young pigs, and respiratory system diseases in the adult.
Affara, NA, Chausiaux, OE, Furlong, RA, Jafer, O, Sargent, CA, Yuan, JF, Zhang, GH, Zhang, SJ   +7 more
core  

Reduced virulence of a pseudorabies virus isolate from wild boar origin in domestic pigs correlates with hampered visceral spread and age-dependent reduced neuroinvasive capacity [PDF]

, 2017
Morbidity and mortality associated with pseudorabies virus (PRV) infection are dependent on the age of the pig and the virulence of the strain. PRV strains circulating in wild boar are considered to be low virulent, but no mechanistic explanation for ...
Cay, Ann Brigitte, De Regge, Nick, Favoreel, Herman, Redant, Valerie, Verpoest, Sara   +4 more
core   +2 more sources

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa [PDF]

, 2011
Several alphaherpesviruses breach the basement membrane during mucosal invasion. In the present study, the role of proteases in this process was examined.
Glorieux, Sarah, Favoreel, Herman, Steukers, Lennert, Vandekerckhove, Annelies, Nauwynck, Hans   +4 more
core   +2 more sources

pH Dependence and Stoichiometry of Binding to the Fc Region of IgG by the Herpes Simplex Virus Fc Receptor gE-gI [PDF]

, 2004
Herpes simplex virus type 1 encodes two glycoproteins, gE and gI, that form a heterodimer on the surface of virions and infected cells. The gE-gI heterodimer has been implicated in cell-to-cell spread of virus and is a receptor for the Fc fragment of IgG.
Bjorkman, Pamela J., Martin, W. Lance, Sprague, Elizabeth R.   +2 more
core   +1 more source

DNA aptamers targeting glycoprotein D enable specific detection of pseudorabies virus (PRV)

Animal Diseases
Abstract Pseudorabies virus (PRV, SuidAlphaherpesvirus 1) causes substantial economic losses in swine production. Here, we report the development of DNA aptamers targeting the PRV glycoprotein D (gD) through an optimized SELEX protocol. After 15 selection cycles, Apt-gD-2 demonstrated nanomolar affinity (Kd = 6.107 ± 0.476 nM) and high ...
Zhihao Wang, Yan Qiao, Jiafu Zhao, Xiaotian Chang, Heshui Zhu, Chao Zhang   +5 more
openaire   +2 more sources

Advances in molecular epidemiology and detection methods of pseudorabies virus

Discover Nano
Pseudorabies (PR), a highly contagious disease caused by the pseudorabies virus (PRV), represents a significant threat to the global swine industry. Despite the success of developed countries in controlling the PRV epidemic through swine pseudorabies ...
Linlin Zhuang, Jiansen Gong, Jingyi Shen, Ying Zhao, Jianbo Yang, Qingxin Liu, Yu Zhang, Qiuping Shen   +7 more
doaj   +1 more source

Age-dependent differences in type I interferon, IL-12 and pro-inflammatory cytokine production by porcine peripheral blood mononuclear cells in response to pseudorabies virus-infected cells

Frontiers in Immunology
Pseudorabies virus is a porcine alphaherpesvirus that causes devastating disease with high mortality in young piglets but much milder, mainly respiratory, problems in older pigs.
Manon S. C. Claeys, Simon G. A. L. Brabant, Stijn Rosschaert, Cliff Van Waesberghe, Herman W. Favoreel   +4 more
doaj   +1 more source

Pseudorabies Virus Induces Viability Changes and Oxidative Stress in Swine Testis Cell-Line [PDF]

, 2013
In this study, we evaluated the association between pseudorabies (PRV) virus-induced viability changes and oxidative stress in vitro cultivated swine testis (ST) cells.
Xiao-Zhan Zhang§1, Ye Chen§1, Hong-Liang Huang§2, Dong-Lei Xu1, Chang-Bao Ren2, Bi-Tao Liu1, Shuo Su1 and Zhao-Xin Tang1, 2*
core  

MiRNA targeting in host-virus interaction: inter-strain comparison in Pseudorabies Virus (PrV)

, 2012
absent
Endale Ahanda, Marie-Laure, Letellier, Thomas, Giuffra, Elisabetta   +2 more
openaire   +2 more sources

Characterisation of Pseudorabies Virus and Its Mutants [PDF]

, 1999
A plaque-purified pseudorabies virus (PrV-mAIP) was established from a field isolate. Following exposure to bromodeoxyuridine (BUdR) and iododeoxyuridine (IUdR), six drug resistant mutants namely PrV-BUdRI, PrVBUdR7, PrV-BUdRlO, PrV-IUdR5, PrV-IUdR9 and ...
Allaudin, Zeenathul Nazariah
core