Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles
Pseudouridine kinase
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
PSEUDOURIDINE DERIVATIVE
Yfii pseudouridine synthase
TLRs are blind to pseudouridine RNA
MODIFICATION OF PSEUDOURIDINE
Stable cystal of protected pseudouridine