Results 141 to 150 of about 2,211 (199)
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Synthesis, hydrolysis and stability of psilocin glucuronide
Forensic Science International, 2014A two-step synthesis of psilocin glucuronide (PCG), the main metabolite of psilocin, with methyl 2,3,4-tri-O-isobutyryl-1-O-trichloroacetimidoyl-α-d-glucopyranuronate is reported. With the synthesized PCG, hydrolysis conditions in serum and urine were optimized. Escherichia coli proved to be a better enzyme source for β-glucuronidase than Helix pomatia.
Jennifer Schürenkamp +2 more
exaly +3 more sources
Detection of psilocin in body fluids
Forensic Science International, 2000Active compounds of some mushrooms e.g. Psilocybe cubensis, Paneolus subalteatus or Stropharia coronilla, the psychotropic agents psilocybin and psilocin, have hallucinogenic effects. In one case of 'magic mushroom' intake, we had to analyse blood and urine. Psilocin was detected in the urine with REMEDi HS.
H Käferstein
exaly +3 more sources
Comparison of psilocin with psilocybin, mescaline and LSD-25
Psychopharmacology, 19621. Reactions induced by LSD, mescaline, psilocin, and psilocybin are qualitatively similar. 2. The time course of the psilocin and psilocybin reactions are shorter than those of LSD or mescaline reactions. li 4. Psilocin is approximately 1.4 times as potent as psilocybin.
E J Miner +2 more
exaly +3 more sources
Immunochemical monitoring of psilocybin and psilocin to identify hallucinogenic mushrooms
Journal of Pharmaceutical and Biomedical Analysis, 2020Development of rapid and reliable immunochemical methods for monitoring psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine; Pyb) and psilocin (dephosphorylated metabolite; Psi), the psychoactive compounds contained within hallucinogenic mushrooms (magic mushrooms), is desirable in order to identify these mushrooms and regulate their illicit use ...
Izumi Morita +2 more
exaly +3 more sources
Development of a psilocin immunoassay for serum and blood samples
International Journal of Legal Medicine, 2004After the immunisation of rabbits with a psilocin-specific immunogen, polyclonal antisera were obtained. With these antisera a competitive, heterogeneous radioimmunoassay for the detection of psilocin was developed. As tracer a derivative of psilocin was synthesised, which contained a tritiated CH(3) group.
J Beike, Kohler H, Brinkmann B
exaly +3 more sources
Psilocin is an active metabolite form of psilocybin and exerts psychoactive effects. Recent studies suggest that psilocin may have regulatory effects on abuse drugs, but the mechanisms remain unclear.
Qing Shang, Hongyan Qian, Xinshe Liu
exaly +2 more sources
Psilocin – The “real deal” or an extraction byproduct
Journal of Forensic Sciences, 2022AbstractMost illicit drug casework samples at the Israel Police National Drug Laboratory are found to be mixtures of substances. Some are a mixture of an illicit drug with fillers, and others may contain more than one illicit drug. This study was triggered by a routine gas chromatography‐mass spectrometry (GC‐MS) analysis of an unusual casework sample.
Ori, Gutman, Dana, Tenne, Uriel, Bretler
openaire +2 more sources
The fate of psilocin in the rat
Biochemical Pharmacology, 1962Abstract The synthesis of 14 C-psilocin labelled in two different positions is described. The resorption, distribution, excretion and metabolism of psilocin in the rat was studied quantitatively with the labelled compounds.
F, KALBERER, W, KREIS, J, RUTSCHMANN
openaire +2 more sources
The Detection of Psilocin in Human Urine
Journal of Forensic Sciences, 2001Abstract Pharmacokinetic studies of psilocybin in humans have shown the rapid dephosphorylation of psilocybin to psilocin with further conversion to 4-hydroxy-tryptophole (4HT) and 4-hydroxyindole-3-acetic acid (4HIAA) in plasma. Our study shows that psilocin also undergoes conjugation and can be found in the urine as the psilocin ...
A F, Grieshaber, K A, Moore, B, Levine
openaire +2 more sources
International Immunopharmacology
BACKGROUND Psilocybin, a serotonergic psychedelic, has demonstrated therapeutic potential in neuropsychiatric disorders. While its neuroplastic and immunomodulatory effects are recognized, the underlying mechanisms remain unclear. This study investigates
Salma Laabi +4 more
semanticscholar +1 more source
BACKGROUND Psilocybin, a serotonergic psychedelic, has demonstrated therapeutic potential in neuropsychiatric disorders. While its neuroplastic and immunomodulatory effects are recognized, the underlying mechanisms remain unclear. This study investigates
Salma Laabi +4 more
semanticscholar +1 more source

