Results 161 to 170 of about 1,626 (211)

Comprehensive analysis of 42 psilocybin-producing fungal strains reveals metabolite diversity and species-specific clusters. [PDF]

Sci Rep
Cohen J, Sulimani L, Procaccia S, Lerenthal Y, Milay L, Taran I, Shapira A, Meiri D.   +7 more
europepmc   +1 more source

Assessing the Potential Cardiovascular Risk of Microdosing the Psychedelic LSD in Mice. [PDF]

ACS Pharmacol Transl Sci
Effinger DP, Schalk SS, King JL, Wallingford JR, O'Connell CK, Calderon JR, Kopecky BJ, McCorvy JD, Thompson SM.   +8 more
europepmc   +1 more source

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Synthesis, hydrolysis and stability of psilocin glucuronide

Forensic Science International, 2014
A two-step synthesis of psilocin glucuronide (PCG), the main metabolite of psilocin, with methyl 2,3,4-tri-O-isobutyryl-1-O-trichloroacetimidoyl-α-d-glucopyranuronate is reported. With the synthesized PCG, hydrolysis conditions in serum and urine were optimized. Escherichia coli proved to be a better enzyme source for β-glucuronidase than Helix pomatia.
Jennifer Schürenkamp, Heidi Pfeiffer, Matthias Lehr   +2 more
exaly   +3 more sources

Detection of psilocin in body fluids

Forensic Science International, 2000
Active compounds of some mushrooms e.g. Psilocybe cubensis, Paneolus subalteatus or Stropharia coronilla, the psychotropic agents psilocybin and psilocin, have hallucinogenic effects. In one case of 'magic mushroom' intake, we had to analyse blood and urine. Psilocin was detected in the urine with REMEDi HS.
H Käferstein
exaly   +3 more sources

Comparison of psilocin with psilocybin, mescaline and LSD-25

Psychopharmacology, 1962
1. Reactions induced by LSD, mescaline, psilocin, and psilocybin are qualitatively similar. 2. The time course of the psilocin and psilocybin reactions are shorter than those of LSD or mescaline reactions. li 4. Psilocin is approximately 1.4 times as potent as psilocybin.
E J Miner, Harris Isbell, Isbell Harris   +2 more
exaly   +3 more sources

Immunochemical monitoring of psilocybin and psilocin to identify hallucinogenic mushrooms

Journal of Pharmaceutical and Biomedical Analysis, 2020
Development of rapid and reliable immunochemical methods for monitoring psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine; Pyb) and psilocin (dephosphorylated metabolite; Psi), the psychoactive compounds contained within hallucinogenic mushrooms (magic mushrooms), is desirable in order to identify these mushrooms and regulate their illicit use ...
Izumi Morita, Hiroyuki Oyama, Jun Ogata   +2 more
exaly   +3 more sources

Development of a psilocin immunoassay for serum and blood samples

International Journal of Legal Medicine, 2004
After the immunisation of rabbits with a psilocin-specific immunogen, polyclonal antisera were obtained. With these antisera a competitive, heterogeneous radioimmunoassay for the detection of psilocin was developed. As tracer a derivative of psilocin was synthesised, which contained a tritiated CH(3) group.
J Beike, Kohler H, Brinkmann B
exaly   +3 more sources

Elucidating the Phase I metabolism of psilocin in vitro

Archives of Toxicology
Psilocin is a well-studied controlled substance with potential psychotherapeutic applications. However, research gaps remain regarding its metabolism. Our objective was to elucidate a comprehensive Phase I metabolic profile of psilocin to support its forensic management and clinical development.
Ziteng Wang, Evelyn Mei Ling Goh, Hooi Yan Moy   +2 more
exaly   +3 more sources

The molecular basis of the antidepressant action of the magic mushroom extract, psilocin

Biochimica Et Biophysica Acta - Proteins and Proteomics, 2023
Magic mushrooms, and their extract psilocybin, are well-known for their psychedelic properties and recreational use. Psilocin, the bio-active form of psilocybin, can potentially treat various psychiatric diseases.
Ali Asghar Hakami Zanjani, Luise Jacobsen, Himanshu Khandelia   +2 more
exaly   +2 more sources