Results 91 to 100 of about 15,597 (227)

Structural basis for psilocybin biosynthesis

Nature Communications
Psilocybin shows significant therapeutic potential for psilocybin-assisted psychotherapy in addressing various psychiatric conditions. The biosynthetic approach promises rapid and efficient production of psilocybin.
Chunyan Meng, Wenting Guo, Chuan Xiao, Yan Wen, Xudong Zhu, Qingrong Zhang, Yuxuan Liang, Hongwei Li, Sha Xu, Yuntan Qiu, Haitao Chen, Wei-Jye Lin, Baixing Wu   +12 more
doaj   +1 more source

The Idealist View of Consciousness After Death [PDF]

, 2016
To make educated guesses about what happens to consciousness upon bodily death, one has to have some understanding of the relationship between body and consciousness during life. This relationship, of course, reflects an ontology.
Kastrup, Bernardo
core  

LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality [PDF]

, 2016
Lysergic acid diethylamide (LSD) is used recreationally and has been evaluated as an adjunct to psychotherapy to treat anxiety in patients with life-threatening illness.
CG Frye, CJ Harmer, CM Hysek, CM Hysek, CM Hysek, CS Grob, DE Nichols, Felix Müller, FX Vollenweider, G Bedi, I Dziobek, KA MacLean, KH Preller, KP Kuypers, M Kometer, Matthias E Liechti, MC Mithoefer, MC Mithoefer, MC Wardle, MC Wardle, MG Kirkpatrick, MG Kirkpatrick, MP Bogenschutz, MW Johnson, P Gasser, P Gasser, P Oehen, P. Strajhar, Patrick C Dolder, Patrick C. Dolder, PC Dolder, R Hurlemann, RL Carhart-Harris, RL Carhart-Harris, RO Murphy, RR Griffiths, RR Griffiths, Stefan Borgwardt, T Passie, W Janke, Y Schmid, Y Schmid, Yasmin Schmid   +42 more
core   +1 more source

Living in the Mycelial World

Topics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source

Psilocybin therapy and anorexia nervosa: a narrative review of safety considerations for researchers and clinicians

Journal of Eating Disorders
Background Clinical trials using psilocybin therapy to treat anorexia nervosa (AN) are currently underway. The safety and tolerability of psilocybin is of utmost importance in individuals with AN who may present unique medical vulnerabilities.
Amanda E. Downey, Anita V. Chaphekar, Joshua Woolley, Marissa Raymond-Flesch   +3 more
doaj   +1 more source

Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans [PDF]

, 2018
Rationale: Binocular rivalry occurs when different images are simultaneously presented to each eye. During continual viewing of this stimulus, the observer will experience repeated switches between visual awareness of the two images.
Carter, Olivia, Hasler, Felix, Liu, Guang, Pettigrew, John, Vollenweider, Franz, Wallis, Guy   +5 more
core  

Integrating the Mystical Experience Questionnaire Into a Broader Psychometric Framework: English Validation of the Psychedelic Experience Scale and Comparison of Psilocybin and LSD Sessions Across Two Controlled Settings

International Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives For English, the validated part of Psychedelic Experience Scale (PES48) is a four‐factor structure called the Mystical Experience Questionnaire (MEQ30). The other validated part of the PES48 consists of four more factors: two more mystical factors (paradoxicality and connectedness, which together with the MEQ30 form the MEQ40), and ...
Kurt Stocker, Matthias Hartmann, Frederick S. Barrett, William A. Richards, Nathan D. Sepeda, Laura Ley, Anna M. Becker, Friederike Holze, Matthias E. Liechti   +8 more
wiley   +1 more source

Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress

Translational Psychiatry
Depression and anxiety are disabling and high incidence mental disorders characterized by phenotypic heterogeneity. Currently available treatments show severe limitations. Thus, there is an urgent need for effective treatments in this population.
Ines Erkizia-Santamaría, Igor Horrillo, Nerea Martínez-Álvarez, Daniel Pérez-Martínez, Guadalupe Rivero, Amaia M. Erdozain, J. Javier Meana, Jorge E. Ortega   +7 more
doaj   +1 more source

The Great God Pan is Not Dead – A. N. Whitehead and the Psychedelic Mode of Perception [PDF]

, 2017
Through Alfred North Whitehead’s metaphysics, the Philosophy of Organism, it will be argued that psychedelic experience is a vertical, lateral and temporal integration of ...
Sjöstedt-H., Peter
core  

Japanese Cohort Study Identifies an Association Between the Serotonin Transporter–Linked Polymorphic Region and Suicide Death

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
The odds ratios and corresponding 95% confidence intervals for suicide death by 5‐HTTLPR S allele, in main and subgroup analyses. Statistical significance is indicated. ABSTRACT Introduction More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people ...
Shohei Okada, Toshiyuki Shirai, Masao Miyachi, Gentaro Yamasaki, Kiriko Minami, Ryo Tsukamoto, Kentaro Mouri, Takaki Tanifuji, Ryuichi Katada, Satoshi Okazaki, Ikuo Otsuka, Akitoyo Hishimoto   +11 more
wiley   +1 more source