Results 91 to 100 of about 10,701 (213)

Level of preparedness to use psilocybin among individuals seeking psychedelic risk reduction: a retrospective study of a pilot psychiatric consultation service

Frontiers in Public Health
IntroductionIn 2020, Oregon became the first US state to legalize state-regulated psilocybin services. This study aims to examine: (1) the clinical and demographic characteristics, (2) psilocybin use motivations, and (3) differences in preparedness among
Harland V. Harrison, Mizan Gaillard, Ryan R. Cook, Aryan Sarparast, Aryan Sarparast, Ximena A. Levander   +5 more
doaj   +1 more source

Psilocybin-assisted therapy for depression: How do we advance the field?

, 2020
In the quest for new treatment options for depression, attention is being paid to the potential role of psychedelic drugs. Psilocybin is of particular interest given its mechanism of action, its benefits in early trials and its relatively low side ...
SL Rossell (14136969), N Strauss (13401207), M Williams (834184), M Ross (13283916), G Murray (9849164), SE Meikle (14865841), P Liknaitzky (14453649), N Thomas (7667738), DJ Castle (11794721)   +8 more
core  

Psilocybin mitigates behavioral despair and cognitive impairment in treatment-resistant depression model using wistar kyoto rats

Scientific Reports
Major depressive disorder (MDD) is a leading cause of disability that affects over 300 million people globally. Despite multiple antidepressant trials, approximately one-third of MDD patients remain symptomatic, progressing to treatment-resistant ...
Zitong Wang, Brett Robbins, Ryan Zhuang, Rebekah van Bruggen, Thaisa Sandini, Xin-Min Li, Yanbo Zhang   +6 more
doaj   +1 more source

Optimized psilocybin production in tryptophan catabolism‐repressed fungi

Microbial Biotechnology
The high therapeutic potential of psilocybin, a prodrug of the psychotropic psilocin, holds great promise for the treatment of mental disorders such as therapy‐refractory depression, alcohol use disorder and anorexia nervosa.
Slavica Janevska, Sophie Weiser, Ying Huang, Jun Lin, Sandra Hoefgen, Katarina Jojić, Amelia E. Barber, Tim Schäfer, Janis Fricke, Dirk Hoffmeister, Lars Regestein, Vito Valiante, Johann E. Kufs   +12 more
doaj   +1 more source

The psychedelic psilocybin and light exposure have similar and synergistic effects on gene expression patterns in the visual cortex

Molecular Brain
Psilocybin, a psychedelic compound found in specific hallucinogenic mushrooms, is known to induce changes in visual perception and experience in humans.
Ram Harari, Dmitriy Getselter, Evan Elliott   +2 more
doaj   +1 more source

Psilocybin for major depressive disorder: a systematic review of randomized controlled studies

Frontiers in Psychiatry
ObjectivesThe purpose of this systematic review of randomized controlled trials (RCTs) was to evaluate the effectiveness, safety, and tolerability of psilocybin in adult patients with major depressive disorder (MDD).MethodsA systematic search (up to ...
Li-Juan Li, Yu Mo, Zhan-Ming Shi, Xing-Bing Huang, Xing-Bing Huang, Yu-Ping Ning, Yu-Ping Ning, Hua-Wang Wu, Hua-Wang Wu, Xin-Hu Yang, Xin-Hu Yang, Wei Zheng, Wei Zheng   +12 more
doaj   +1 more source

Psilocybin and Depression: Past Psilocybin Use Improving Future Depressive Symptom Management

, 2021
In this study, I investigated whether individuals who have taken psilocybin in the past felt that their experience(s) helped them prevent or cope with depressive symptoms.
Hansen, Taylor
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Attitudes Towards Psilocybin: A General Population’s Opinions on Psilocybin and Psilocybin-Assisted Therapies

Psi Chi Journal of Psychological Research
Psilocybin-assisted therapies (PAT) have been used to treat several issues including obsessive-compulsive disorder (OCD), major depressive disorder (MDD), posttraumatic stress disorder (PTSD), smoking addiction, and anxiety (Grob et al., 2011; Johnson et al., 2014; Kisely et a., 2022; Moreno et al., 2006).
Madison M. H. Simounet, Joy R. Drinnon
openaire   +1 more source

Revealing shortcomings in the assessment of psilocybin effects on OCD-related symptoms in preclinical and clinical studies: A systematic review

Journal of Affective Disorders Reports
Psilocybin is a chemical compound found in certain types of hallucinogenic mushrooms, known as magic mushrooms. Evidence has shown potential therapeutic effects of psilocybin on different neuropsychiatric disorders such as major depressive disorder (MDD),
Marzieh Jalalian-Javadpour, Batool Ghorbani Yekta, Niloufar Reyhani, Shadi Hajizamani, Ali Azizi, Najma Khoshrooz Azad, Hamidreza Mohammadi, Salar Vaseghi   +7 more
doaj   +1 more source

Amid magic and menace: psychiatrists' attitudes to psilocybin therapy.

OBJECTIVES Understanding variations in knowledge and attitudes of psychiatrists to psilocybin therapy is important for the collective discourse about the potential impact on clinical practice and public health in Ireland.
Ivers, Jo-Hanna, Tobin, Katy, Harrington, Colm, Hendricks, Peter S, Gribben, Andrew, Murnane, Kevin S, Kelly, John R, Thuery, Guillaume, Burke, Tara, Husein, Amanda, Harkin, Andrew   +10 more
core   +1 more source