Results 111 to 120 of about 15,597 (227)

The NMDA antagonist ketamine and the 5-HT agonist psilocybin produce dissociable effects on structural encoding of emotional face expressions [PDF]

, 2018
Rationale: Both glutamate and serotonin (5-HT) play a key role in the pathophysiology of emotional biases. Recent studies indicate that the glutamate N-methyl-d-aspartate (NMDA) receptor antagonist ketamine and the 5-HT receptor agonist psilocybin are ...
Bachmann, Rosilla, Kometer, Michael, Schmidt, André, Seifritz, Erich, Vollenweider, Franz   +4 more
core  

Psychedelic therapy from an existential psychological viewpoint : a theoretical analysis [PDF]

, 2016
Clinical research into the therapeutic applications of classical psychedelics has slowly but steadily resumed over the last couple of decades. Continuing the research that went dormant in the late 1960‟s, modern trials are looking into the use of high ...
Berg, Stian Hyman
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The effect of psilocybin on empathy and prosocial behavior: a proposed mechanism for enduring antidepressant effects

npj Mental Health Research
Psilocybin is a serotonergic psychedelic shown to have enduring antidepressant effects. Currently, the mechanism for its enduring effects is not well understood. Empathy and prosocial behavior may be important for understanding the therapeutic benefit of
Kush V. Bhatt, Cory R. Weissman
doaj   +1 more source

Attitudes Towards Psilocybin: A General Population’s Opinions on Psilocybin and Psilocybin-Assisted Therapies

Psi Chi Journal of Psychological Research
Psilocybin-assisted therapies (PAT) have been used to treat several issues including obsessive-compulsive disorder (OCD), major depressive disorder (MDD), posttraumatic stress disorder (PTSD), smoking addiction, and anxiety (Grob et al., 2011; Johnson et al., 2014; Kisely et a., 2022; Moreno et al., 2006).
Madison M. H. Simounet, Joy R. Drinnon
openaire   +1 more source

A narrative exploration of psilocybin’s potential in mental health

Frontiers in Psychiatry
Psilocybin, a psychoactive substance, has recently garnered attention for its high therapeutic potential in psychiatry. In this study, we investigated the multifaceted aspects of psilocybin, highlighting its chemical properties, mechanisms of action, and
Huitae Min, Soon Young Park, Jisu Park, Jisu Park, Seongsu Na, Seongsu Na, Hoe-Suk Lee, Taejung Kim, Taejung Kim, Jungyeob Ham, Jungyeob Ham, Jungyeob Ham, Young-Tae Park, Young-Tae Park   +13 more
doaj   +1 more source

Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats

Frontiers in Neuroscience
Psilocybin is a hallucinogen with complex neurobiological and behavioral effects. This is the first study to use MRI to follow functional changes in brain activity in response to different doses of psilocybin in fully awake, drug naive rats.
Evan Fuini, Arnold Chang, Richard J. Ortiz, Richard J. Ortiz, Taufiq Nasseef, Josh Edwards, Marc Latta, Elias Gonzalez, Taylor J. Woodward, Bryce Axe, Ashwath Maheswari, Noah Cavallaro, Heather B. Bradshaw, Praveen P. Kulkarni, Craig F. Ferris, Craig F. Ferris   +15 more
doaj   +1 more source

Drug Laws, Ethics, and History [PDF]

, 2019
In this paper, I present and criticize several historical arguments in favour of prohibition and criminalization of illicit psychoactive substances. I consider several versions of Charles Brent’s argument from drug harms and an argument
Greif, Adam
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Case Report: Repeated low doses of psilocybin reduce perceived symptom severity but fail to restore cognitive flexibility in a case of severe obsessive-compulsive disorder: an observational case study of identical twins

Frontiers in Psychiatry
BackgroundObsessive-Compulsive Disorder (OCD) can present significant challenges to individuals mental health, characterized by intrusive thoughts and repetitive maladaptive behaviors.
Sivert Drange, Sivert Drange, Jacob Cohen, Jacob Cohen, Jacob Cohen, Jacob Cohen, Sys Stybe Johansen, Ben Dunkley, Mikael Palner, Mikael Palner, Mikael Palner   +10 more
doaj   +1 more source

The most profound spiritual autobiography of all time? - a review of "The Knee of Listening" by Adi Da (Franklin Jones) (1995) (review revised 2019) [PDF]

, 2019
A brief review of the life and spiritual autobiography of the unique American mystic Adi Da (Franklin Jones). The sticker on the cover of some editions says `The most profound spiritual autobiography of all time` and this might well be true.
Starks, Michael
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Behandeling met psilocybine

Nederlands Tijdschrift voor Geneeskunde, 2021
After a cessation of almost 40 years, there is renewed interest into therapeutic applicationsof the serotonergic psychedelic psilocybin for the treatment of patients with various psychiatric disorders. PubMed was searched for clinical trials into "psilocybin" between 2000 and 2020, complemented by handsearching.
Breeksema, Joost J, Koolen, Martijn H B, Somers, Metten, Schoevers, Robert A   +3 more
openaire   +1 more source