Biological Research, 2019 Background Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom.
Xiaomin Wang +5 more
doaj +1 more source
Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair. [PDF]
PLoS Genetics, 2008 DNA interstrand crosslinks (ICLs) are among the most toxic types of damage to a cell. For this reason, many ICL-inducing agents are effective therapeutic agents.
Qi Wu, Karen M Vasquez
doaj +1 more source
The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]
, 2016 BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael +10 more
core +3 more sources
Journal of Orthopaedic Surgery and Research, 2023 Objective To explore the mechanism of psoralen synergized with exosomes (exos)-loaded SPC25 on nucleus pulposus (NP) cell senescence in intervertebral disc degeneration (IVDD).
Lei Yang +6 more
doaj +1 more source
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. [PDF]
, 1992 The Boltzmann transport equation is commonly considered to be the best semi-classical description of carrier transport in semiconductors, providing precise information about the distribution of carriers with respect to time (one dimension), location ...
Birnstiel, Max L. +5 more
core +2 more sources
Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability
Frontiers in Pharmacology, 2018 Psoralen is a major component of the common traditional Chinese medicine Fructus Psoraleae (FP). In this study, we focused on psoralen to explore FP-induced hepatotoxicity and the underlying mechanisms.
Wang Zhou +12 more
doaj +1 more source
Divergent RNA transcription:A role in promoter unwinding? [PDF]
, 2013 New approaches using biotinylated-psoralen as a probe for investigating DNA structure have revealed new insights into the relationship between DNA supercoiling, transcription and chromatin compaction.
Corless, Samuel +2 more
core +1 more source
In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies
Journal of Pharmacy and Bioallied Sciences, 2015 Introduction: Alzheimer′s disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD ...
Gauresh Somani +5 more
doaj +1 more source
Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]
, 1981 A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Altmann +34 more
core +2 more sources
DETECTION OF HYDROPEROXIDES IN SOLUTIONS OF PHOTOOXIDIZED PSORALEN
Тонкие химические технологии, 2019 Photooxidized psoralen solutions possess a variety of biological effects, which implementation mechanism may presumably involve hydroperoxides. Here, the hydroperoxide content in photooxidized psoralen solutions was assessed using photometric FOX assay ...
V. V. Skarga +4 more
doaj +1 more source