Results 21 to 30 of about 21,032 (282)

Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]

, 1981
A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Altmann, Berns, Berns, Berns, Berns, Berns, Berns, Berns, Berns, Berns, Burkhardt, Cain, Cremer, Cremer, Cremer, Cremer, Dreher, Factor, Geisinger, Hetzel, Kitzes, Leder, Leuchtenberger, Meredith, Moreno, Nakanishi, Peterson, Rattner, Schneider, Scott, Stevenson, Strahs, Tam, Tchakhotine, Wang   +34 more
core   +2 more sources

A Review of the Pharmacological Properties of Psoralen

Frontiers in Pharmacology, 2020
Psoralen is the principal bioactive component in the dried fruits of Cullen corylifolium (L.) Medik (syn. Psoralea corylifolia L), termed “Buguzhi” in traditional Chinese medicine (TCM).
Yali Ren, Xiaominting Song, Lu Tan, Chuanjie Guo, Miao Wang, Hui Liu, Zhixing Cao, Yuzhi Li, Cheng Peng   +8 more
doaj   +1 more source

In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

Journal of Pharmacy and Bioallied Sciences, 2015
Introduction: Alzheimer′s disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD ...
Gauresh Somani, Chinmay Kulkarni, Prashant Shinde, Rupesh Shelke, Kirti Laddha, Sadhana Sathaye   +5 more
doaj   +1 more source

Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]

, 2016
Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Sandra, Koen, t'Kindt, Ruben, Van Aelst, Britt, Vandekerckhove, Philippe, Zachée, Pierre   +7 more
core   +2 more sources

In vitro demonstration of herbal exacerbation of paracetamol-induced hepatotoxicity

Phytomedicine Plus, 2022
Background: Paracetamol (acetaminophen) is one of the most accessible pharmaceutical analgesic and antipyretic agents. Similarly, traditional herbal medicines including Psoralea corylifolia, Astragalus propinquus and Atractylodes macrocephala have been ...
Susan M. Britza, Rachael Farrington, Roger W. Byard, Ian F. Musgrave   +3 more
doaj   +1 more source

The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]

, 2016
BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael, Bhutani, Tina, DaLovisio, Renee, Farahnik, Benjamin, Jose, Margareth V, Koo, John, Lee, Kristina M, Liao, Wilson, Nakamura, Mio, Singh, Rasnik K, Zhu, Tian Hao   +10 more
core   +3 more sources

Psoralen

, 2020
National Cancer Institute
openaire   +2 more sources

Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells [PDF]

, 2017
Previous results link the mitochondrial potassium channel Kv1.3 (mitoKv1.3) to the regulation of apoptosis. By synthesizing new, mitochondria-targeted derivatives (PAPTP and PCARBTP) of PAP-1, a specific membrane-permeant Kv1.3 inhibitor, we have ...
Amigorena, Arcangeli, Beeton, Cahalan, Checchetto, Chittajallu, Cholo, Cidad, Comes, Connor, Deutsch, Diebold, Diwakarla, Doyle, Erdogan, Esteras, Fraser, Ghiani, Heginbotham, Hinz, Hu, Jang, Koren, Leanza, Leanza, Leanza, Lin, Long, Lu, Malinska, Manago, Nilius, Pardo, Peruzzo, Ralph, Ralph, Rauer, Shieh, Siegel, Szabo, Szabo, Tegla, Tonks, Urrego, Van Rensburg, Xu, Zaccagnino, Zhou, Zucca   +48 more
core   +2 more sources

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

A Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy [PDF]

, 2018
Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases.
Ahmad, Archier, Archier, Aslam, Atzmony, Aydogan, Behrens-Williams, Berroeta, Bhatnagar, Bhatnagar, Bilsland, Bilsland, Bishnoi, Boswell, Brazzelli, Bruynzeel, Calzavara-Pinton, Calzavara-Pinton, Cameron, Cameron, Carter, Chalmers, Chauhan, Chen, Clayton, Collins, Cunningham, Dawe, Dawe, Dawe, Dawe, De, Decock, Der-Petrossian, Diederen, El-Mofty, Engin, Farnaghi, Fernandez-Guarino, Foerster, Garritsen, George, Godt, Gordon, Grandi, Green, Grundmann-Kollmann, Halpern, Harrop, Healy, Hearn, Hindson, Hindson, Hofer, Holme, Hoot, Hudson-Peacock, Ibbotson, Ibbotson, Iraji, Karvonen, Kerscher, Khafagy, Knobler, Kolde, Larko, Lever, Lindelof, Ling, Man, Man, Man, Man, Markham, Mastalier, Mckenna, Menage, Messenger, Millington, Mobacken, Mohamed, Morgado-Carrasco, Murray, Norris, Olsen, Parrish, Pavlovsky, Radakovic, Robinson, Roelandts, Roelandts, Ros, Rosen, Rosen, Rosen, Salem, Sapam, Sevrain, Sezer, Sivaramakrishnan, Snellman, Solak, Stern, Stern, Stern, Stern, Stern, Stern, Tanew, Tanew, Taylor, Tegner, Tzaneva, Van, Van, Wackernagel, Warren, Westerhof, Yones, Yones   +119 more
core   +3 more sources