Results 111 to 120 of about 293,751 (369)

Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis [PDF]

, 2012
D6 is a scavenging-receptor for inflammatory CC chemokines that are essential for resolution of inflammatory responses in mice. Here, we demonstrate that D6 plays a central role in controlling cutaneous inflammation, and that D6 deficiency is associated ...
Anne Thorrat, Antal Rot, Codullo, David Burden, Fra, Gerard J. Graham, Graham, Gudjonsson, Helen Baldwin, Homey, Iain B. McInnes, Jamieson, Johnston, Jose M. Carballido, Kave Shams, Kenneth Pallas, Kit Ming Lee, Madigan, Mantovani, Mark D. Singh, Martinez de la Torre, Martinez de la Torre, McKimmie, Nestle, Nibbs, Nibbs, Nibbs, Nickoloff, Nickoloff, Rot, Ruairidh Nicoll, Ruchatz, Susan Holmes, Thomas Jamieson, van de Kerkhof, Vetrano, Vicky King, Weber, Whitehead, Yoshinaga   +39 more
core   +1 more source

Model of pathogenesis of psoriasis. Part 1. Systemic psoriatic process [PDF]

arXiv, 2011
Analytical study of results of experimental and theoretical works on pathogenesis of psoriatic disease was conducted. Psoriasis is dermal implication of systemic psoriatic process (SPP). New SPP model explaining results of clinical and laboratory experiments was formulated.
arxiv  

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

Arthritis &Rheumatology, EarlyView.
Objective A pathogenetic role of CD8+ T lymphocytes in radiographic axial spondyloarthritis (r‐axSpA) and other spondyloarthritis (SpA) is sustained by genome‐wide association studies and by the expansion of public T cell clonotypes in the target tissues.
Giorgia Paldino, Valentina Tedeschi, Valentina Proganò, Erica Salvati, Valerio Licursi, Eleonora Vertecchi, Alexandru L. Bivolaru, Emanuele Molteni, Rossana Scrivo, Mattia Congia, Alberto Cauli, Rosalba Caccavale, Marino Paroli, Martina Kunkl, Loretta Tuosto, Rosa Sorrentino, Maria Teresa Fiorillo   +16 more
wiley   +1 more source

Association between systemic immune inflammation index, systemic inflammation response index and adult psoriasis: evidence from NHANES

Frontiers in Immunology
BackgroundThe systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) are both novel biomarkers and predictors of inflammation. Psoriasis is a skin disease characterized by chronic inflammation.
Rui Ma, Rui Ma, Lian Cui, Lian Cui, Jiangluyi Cai, Jiangluyi Cai, Nan Yang, Nan Yang, Yuanyuan Wang, Yuanyuan Wang, Qianyu Chen, Qianyu Chen, Wenjuan Chen, Wenjuan Chen, Chen Peng, Chen Peng, Hui Qin, Hui Qin, Yangfeng Ding, Yangfeng Ding, Xin Wang, Xin Wang, Qian Yu, Qian Yu, Yuling Shi, Yuling Shi   +25 more
doaj   +1 more source

Recent advances in phototherapy for psoriasis [version 1; referees: 2 approved]

F1000Research, 2016
Phototherapy involves repeated exposure of the skin to ultraviolet light to treat various inflammatory skin conditions such as psoriasis. Recent studies have identified specific immunologic effects of phototherapy that may underlie phototherapy efficacy.
Mio Nakamura, Benjamin Farahnik, Tina Bhutani   +2 more
doaj   +1 more source

Comparison between Intralesional Triamcinolone and Kligman's Formula in Treatment of Melasma

Acta Medica Iranica, 2016
Melasma is a common acquired skin disorder. While different treatments are currently being used, in many cases it is refractory to treatment. According to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this ...
Gholamreza Eshghi, leila khezrian, Fariba Esna Ashari   +2 more
doaj  

Positive association between insulin resistance and fatty liver disease in psoriasis: evidence from a cross-sectional study

Frontiers in Immunology
BackgroundFatty liver disease (FLD) is a common comorbidity of psoriasis and is often referred to as non-alcoholic fatty liver disease (NAFLD). However, the role of inflammation or insulin resistance (IR) in FLD is inconclusive. The study aims to explore
Xiaoyuan Zhong, Xiaoyuan Zhong, Dawei Huang, Dawei Huang, Rongfen Chen, Rongfen Chen, Lingling Yao, Lingling Yao, Rui Ma, Rui Ma, Yingyuan Yu, Yingyuan Yu, Yuxiong Jiang, Yuxiong Jiang, Luyang Kong, Luyang Kong, Jiajing Lu, Jiajing Lu, Ying Li, Ying Li, Yuling Shi, Yuling Shi   +21 more
doaj   +1 more source

Data Mining and Analytical Models to Predict and Identify Adverse Drug-drug Interactions [PDF]

arXiv, 2020
The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better identification and prediction of administration of known DDIs in primary and secondary care could reduce the ...
arxiv  

Effects of Secukinumab on Enthesiophyte and Erosion Progression in Psoriatic Arthritis: A One‐Year Double‐Blind, Randomized, Placebo‐Controlled Trial Using High‐Resolution Peripheral Quantitative Computed Tomography

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to ascertain the effect of secukinumab on erosion and enthesiophyte progression in psoriatic arthritis (PsA) by using high‐resolution peripheral quantitative computed tomography (HR‐pQCT). Methods This was a phase 4, double‐blind, randomized, placebo‐controlled trial.
Yingzhao Jin, Isaac T. Cheng, Ho So, Billy T. Lai, Shirley K. Ying, Kitty Y. Kwok, James Griffith, Vivian Hung, Cheuk‐Chun Szeto, Jack J. Lee, Ling Qin, Lai‐Shan Tam   +11 more
wiley   +1 more source

The pathological role of Wnt5a in psoriasis and psoriatic arthritis. [PDF]

, 2019
Psoriasis (PsO) is a chronic inflammatory skin disease with both local and systemic components. PsO-associated arthritis, known as psoriatic arthritis (PsA), develops in approximately 13%-25% of PsO patients.
Li, Zhengxiao, Mauro, Theodora M, Tian, Faming   +2 more
core   +1 more source