Results 121 to 130 of about 184,542 (286)

Targeting CLEC4E in immunosuppressive tumour‐associated macrophages via BET inhibition

Clinical and Translational Medicine
Background Immunosuppressive tumour‐associated macrophages (TAMs) represent a promising target for cancer immunotherapy; however, existing TAM‐directed therapies have shown limited clinical efficacy. C‐type lectin domain family 4 member E (CLEC4E), a pro‐
Mengting Liao, Kexin Long, Liang Dong, Zhuo Li, Wenhua Wang, Rui Hu, Yangyi Zhang, Juan Su, Wu Zhu, Xiang Chen, Mingzhu Yin   +10 more
doaj   +1 more source

BIOME cohort: Multi‐system microbiome dynamics and clinical outcomes in massive burn injury patients

iMeta, EarlyView.
Massive burn injuries (MBIs) are associated with high mortality and disability rates, primarily due to microbial‐driven sepsis from extensive skin barrier loss and subsequent scar formation. This makes MBI a compelling model for studying multi‐system microbial dysbiosis following skin barrier destruction.
Runzhi Huang, Yixu Li, Xiaoliang Li, Xulin Chen, Gang Xu, Shurun Huang, Weixi Yang, Xiaodong Li, Haiming Xin, Jianqiang Jiao, Hui Chen, Yuguo Xie, Peng Duan, Wenjun Liu, Xiangdong Deng, Zongyu Li, Yiping Xiu, Jiansheng Zheng, Rujun Chen, Zhaohong Chen, Xingang Wang, Xiaojian Li, Gaoxing Luo, Yi Zhang, Hongyan Zhang, Shichu Xiao, Liang Xiao, Ruijin Guo, Jie Zhang, Xiaofei Ye, Hongtai Tang, Qiao Zuo, Bin Qu, Bingwei Sun, Changhong Lu, Chengliang Deng, Deyi Zheng, Geng Ji, Haisheng Li, Haizhou Yu, Hua Zhou, Jian Wu, Lanjun Nie, Lei Wang, Pihong Zhang, Qingfu Zhang, Shengwu Chao, Sisi Yang, Xianglin Ding, Xiangsheng Ding, Ying Yan, Jiangyong Shen, Yongjian Zhao, Yunchuan Pan, Yunbiao Shen, Yu Zhang, Zhihui Yao, Zhe Cheng, Jiangfan Xie, Zhigang Chu, Shijie Li, Long Xu, Xiuming Yang, Sujie Xie, Hanlin Sun, Shuyuan Xian, Dezhi Han, Maolong Dong, Chengde Xia, Peng Luo, Yongming Yao, Zhaofan Xia, Shizhao Ji   +72 more
wiley   +1 more source

LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation

Cell Discovery
The role of CD8+ tissue-resident memory T (CD8+ TRM) in inflammation is well established. However, the mechanisms by which CD8+ TRM cells are activated in tissues have remained elusive.
Rundong Jiang, Zhiqin Fang, Yutong Wang, Bo Huang, Junkun Liu, Lam C. Tsoi, Rachael Bogle, Zongbo Zhang, Yehong Kuang, Xin Li, Liang Dong, Liping Jin, Johann E. Gudjonsson, Mingzhu Yin, Xiang Chen   +14 more
doaj   +1 more source

Comparison of Treatment Goals for Moderate-to-Severe Psoriasis between Korean Dermatologists and the European Consensus Report

, 2015
Sang Woong Youn, Bo Ri Kim, Joo Heung Lee, Hae Jun Song, Yong Beom Choe, Ji Ho Choi, Nack In Kim, Kwang Joong Kim, Jai Il Youn   +8 more
openalex   +1 more source

Topical Application of Ursolic Acid Cream Ameliorates Imiquimod-induced Plaque Psoriasis in BALB/c Mice

, 2023
Precious Derera, M. Sumithra, V. Chitra, R. Mrinalini, Rukaiah Fatma Begum   +4 more
openalex   +2 more sources

Exploring the Link Between Psoriasis and Genetic Predictors of Cardiac Magnetic Resonance Traits: A Bidirectional Mendelian Randomization Study

iNew Medicine, EarlyView.
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang, Pengzhan Yin, Shutian An, Zhanglei Li, Yewen Jiang, Jun Wang, Yongqiang Yu, Ren Zhao, Xiaohu Li   +8 more
wiley   +1 more source

Generalized pustular psoriasis treated with apremilast in a patient with multiple medical comorbidities

JAAD Case Reports, 2017
Caleb Jeon, BS, Mio Nakamura, MD, Sahil Sekhon, MD, Di Yan, BA, Jashin J. Wu, MD, Wilson Liao, MD, Tina Bhutani, MD   +6 more
doaj   +1 more source

Psoriasis: A Comprehensive Review of Diagnosis and Treatment

, 2023
Dheeraj Kumar Maheshwari, Hariharan Subramanian, Krishna Prasanth Baalann, Rama Prasad Padhy, Sagar N. Ande, Poonam Popatrao Taru, D. J. C., Muhammed Ameen, G. Dharmamoorthy   +8 more
openalex   +1 more source

TAM pathway proteins as novel salivary biomarkers for periodontitis

Journal of Periodontology, EarlyView.
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes, Ana T. P. C. Gomes, Dimitris N. Tatakis, Tiago Marques, Marla Pinto, Pedro C. Lopes, Maria J. Correia, Nuno Rosa   +7 more
wiley   +1 more source

Dermoscopy for the Differentiation of Subacute Cutaneous Lupus Erythematosus from Other Erythematous Desquamative Dermatoses—Psoriasis, Nummular Eczema, Mycosis Fungoides and Pityriasis Rosea [PDF]

Magdalena Żychowska, Kinga Kołcz
openalex   +1 more source