Results 241 to 250 of about 272,684 (347)
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source
The Role of Selected Proteins in the Pathogenesis of Psoriasis. [PDF]
Matwiejuk M+5 more
europepmc +1 more source
Anti‐Inflammatory Saponins From an Edible Aquatic Plant Nymphoides hydrophylla
ABSTRACT Introduction The present investigation of Nymphoides hydrophylla is a Taiwan indigenous edible aquatic plant, belongs to the Menyanthaceae family, and has been used as a traditional food with potential medicinal values against fever, insect bites, ulcer, and skin diseases.
Ching‐Yeu Chen+6 more
wiley +1 more source
IL-17 A expression negatively correlates with γδ T-Cell density in human psoriasis lesions: a novel implication for disease pathogenesis. [PDF]
Sevgin K+6 more
europepmc +1 more source
ABSTRACT First‐line therapeutic approaches for Crohn's disease include immunosuppressants, aminosalicylates, and corticosteroids. However, more than one‐third of patients are resistant to these treatments and require second‐line therapies. Our goal was to synthesize the evidence on the efficacy and safety of biologics and small molecules for inducing ...
Daniela Gorski+5 more
wiley +1 more source
ABSTRACT Rocatinlimab (AMG 451/KHK4083) is a potential T‐cell rebalancing therapy that inhibits and reduces the number of pathogenic T cells by targeting the OX40 receptor; it is associated with a progressive and sustained response for patients with moderate‐to‐severe atopic dermatitis (AD).
Hiroki Okada+8 more
wiley +1 more source
Dynamic trend analysis of global psoriasis burden from 1990 to 2021: a study of gender, age, and regional differences based on GBD 2021 data. [PDF]
Xiong J, Xue T, Tong M, Xu L, Bai B.
europepmc +1 more source