Results 251 to 260 of about 272,684 (347)

Pharmacometric Model‐Based Sample Size Allocation for a Region of Interest in a Multi‐Regional Phase 2 Trial: A Case Study of an Anti‐Psoriatic Drug

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Pharmacometric model‐based sample size allocation for a region of interest in a multi‐regional phase 2 trial: A case study of an anti‐psoriatic drug. ABSTRACT Phase 2 trials have historically focused on characterizing the dose‐exposure‐response relationship in relatively homogeneous patient populations before proceeding to confirmatory trials. However,
Xiao Zhang   +4 more
wiley   +1 more source

Criteria for Dose Adjustment of Tildrakizumab in Psoriasis Vulgaris

open access: yes
JEADV Clinical Practice, EarlyView.
Andreas Pinter   +2 more
wiley   +1 more source

Potential Therapeutic Actions of Flavonoids Present in Propolis That Modulate Vascular Endothelial Growth Factor Signaling to Regulate Angiogenesis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Propolis is a plant‐derived substance collected by honeybees that has a range of potential therapeutic applications. Propolis consists of resins, waxes, and fatty acids, as well as essential oils and other organic compounds. The pharmacologically active components of propolis include phenols and flavonoids, among others.
Yipeng Lin   +7 more
wiley   +1 more source

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis1

open access: yesJournal of Immunology, 2009
L. van der Fits   +10 more
semanticscholar   +1 more source

Mitochondrial dynamics in autoimmune diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma   +5 more
wiley   +1 more source

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