Results 31 to 40 of about 184,542 (286)

Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients

Frontiers in Cell and Developmental Biology, 2022
Background: Psoriasis is a common immune-mediated skin disease that involves T-cell-mediated immunity. Invariant natural killer T (iNKT) cells are a unique lymphocyte subpopulation that share properties and express surface markers of both NK cells and T ...
Yifan Hu, Yifan Hu, Yifan Hu, Youdong Chen, Youdong Chen, Zeyu Chen, Zeyu Chen, Xilin Zhang, Xilin Zhang, ChunYuan Guo, ChunYuan Guo, ZengYang Yu, ZengYang Yu, Peng Xu, Peng Xu, Lei Sun, Lei Sun, Xue Zhou, Xue Zhou, Yu Gong, Yu Gong, Qian Yu, Qian Yu, Yuling Shi, Yuling Shi, Yuling Shi   +25 more
doaj   +1 more source

Development of bullous pemphigoid during treatment of psoriasis with ustekinumab: a case report and literature review

Frontiers in Medicine, 2023
Ustekinumab is a biological therapy that has been approved for treating moderate-to-severe psoriasis. Although injection site reactions, nasopharyngitis, headaches, and infections are the common adverse events associated with ustekinumab, the development
Luyang Kong, Luyang Kong, Dawei Huang, Dawei Huang, Jiajing Lu, Jiajing Lu, Yuexin Zhang, Yuexin Zhang, Ying Li, Ying Li, Xuemei Yi, Xuemei Yi, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source

Positive association between different triglyceride glucose index-related indicators and psoriasis: evidence from NHANES

Frontiers in Immunology, 2023
BackgroundPsoriasis is a chronic inflammatory skin disease with effects that extend beyond the skin. Insulin resistance (IR) has been associated with psoriasis, but it remains unclear how indicators related to the triglyceride glucose (TyG) index, which ...
Dawei Huang, Dawei Huang, Rui Ma, Rui Ma, Xiaoyuan Zhong, Xiaoyuan Zhong, Yuxiong Jiang, Yuxiong Jiang, Jiajing Lu, Jiajing Lu, Ying Li, Ying Li, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source

Long-term efficacy and safety of guselkumab in Chinese patients with moderate-to-severe plaque psoriasis

Frontiers in Medicine, 2023
BackgroundRandomized controlled trials indicated guselkumab, the first anti-interleukin-23 monoclonal antibody, is efficacious in plaque psoriasis. However, guselkumab's performance in real life is scarcely examined, especially in China.ObjectivesThis ...
Jianfeng Zheng, Jianfeng Zheng, Wenjuan Chen, Wenjuan Chen, Xuemei Yi, Xuemei Yi, Ning Yu, Ning Yu, Yangfeng Ding, Yangfeng Ding, Yunlu Gao, Yunlu Gao   +11 more
doaj   +1 more source

Cardiometabolic Comorbidities in Patients With Psoriasis: Focusing on Risk, Biological Therapy, and Pathogenesis

Frontiers in Pharmacology, 2021
Psoriasis is a chronic inflammatory disease characterized by erythematous scaly plaques, accompanied by systemic damage that leads to the development of multiple comorbidities.
Jiangluyi Cai, Jiangluyi Cai, Lian Cui, Lian Cui, Yu Wang, Yu Wang, Ying Li, Ying Li, Xilin Zhang, Xilin Zhang, Yuling Shi, Yuling Shi   +11 more
doaj   +1 more source

Hydrocolloid‐Based Multiwavelength Stretchable QD‐OLED Patch for Simultaneous Neonatal Jaundice and Dermatitis Treatment with Biosignal Monitoring

Advanced Healthcare Materials, EarlyView.
Comparison of therapeutic and diagnostic applications of a surface‐emitting light source with multiwavelength emission characteristics. Abstract Conventional light‐emitting‐diode‐based light sources suffer from rigidity, localized heating, and poor adaptability to skin deformation, limiting their use in skin‐attached medical devices.
In Ho Kim, Young Woo Kim, Jae‐Young Jeong, Ye Ji Shin, Chaeyeong Lee, Jae Gyun Choi, Oh Kwan Kwon, Kyoung Hwa Kim, Sang Jik Kwon, Eou‐Sik Cho, Yongmin Jeon   +10 more
wiley   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Janus kinase inhibitors in autoimmune bullous diseases

Frontiers in Immunology, 2023
Autoimmune bullous disease (AIBD) is a severe skin disorder caused by autoantibodies that target intercellular or cell-matrix adhesion proteins.
Dawei Huang, Dawei Huang, Yuexin Zhang, Yuexin Zhang, Luyang Kong, Luyang Kong, Jiajing Lu, Jiajing Lu, Yuling Shi, Yuling Shi   +9 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source