Results 31 to 40 of about 161,729 (326)

Positive association between different triglyceride glucose index-related indicators and psoriasis: evidence from NHANES

Frontiers in Immunology, 2023
BackgroundPsoriasis is a chronic inflammatory skin disease with effects that extend beyond the skin. Insulin resistance (IR) has been associated with psoriasis, but it remains unclear how indicators related to the triglyceride glucose (TyG) index, which ...
Dawei Huang, Dawei Huang, Rui Ma, Rui Ma, Xiaoyuan Zhong, Xiaoyuan Zhong, Yuxiong Jiang, Yuxiong Jiang, Jiajing Lu, Jiajing Lu, Ying Li, Ying Li, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source

Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population‐based cohort study

Autism Research, Volume 15, Issue 12, Page 2371-2380, December 2022., 2022
Abstract The aim of this study was to examine potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with autism spectrum disorder (ASD) in offspring. Both exposures have been associated with increased risk of ASD in previous studies, but potential synergistic effects remain underexplored.
Timothy C. Nielsen, Natasha Nassar, Antonia W. Shand, Hannah F. Jones, Velda X. Han, Shrujna Patel, Adam J. Guastella, Russell C. Dale, Samantha J. Lain   +8 more
wiley   +1 more source

Early morphea simulating patch-stage mycosis fungoides in two cases

Dermatology Reports, 2018
Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other ...
Hamid R. Ghasemi Basir, Pedram Alirezaei, Aliasghar Rezanejad, Sajjad Daneshyar   +3 more
doaj   +1 more source

Psoriasis and Genetics

Acta Dermato Venereologica, 2020
Psoriasis is a common inflammatory skin disease caused by the interplay between multiple genetic and environmental risk factors. This review summarises recent progress in elucidating the genetic basis of psoriasis, particularly through large genome-wide association studies.
Dand, Nick, Mahil, Satveer K, Capon, Francesca, Smith, Catherine H, Simpson, Michael A, Barker, Jonathan N   +5 more
openaire   +6 more sources

Cardiometabolic Comorbidities in Patients With Psoriasis: Focusing on Risk, Biological Therapy, and Pathogenesis

Frontiers in Pharmacology, 2021
Psoriasis is a chronic inflammatory disease characterized by erythematous scaly plaques, accompanied by systemic damage that leads to the development of multiple comorbidities.
Jiangluyi Cai, Jiangluyi Cai, Lian Cui, Lian Cui, Yu Wang, Yu Wang, Ying Li, Ying Li, Xilin Zhang, Xilin Zhang, Yuling Shi, Yuling Shi   +11 more
doaj   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Development of bullous pemphigoid during treatment of psoriasis with ustekinumab: a case report and literature review

Frontiers in Medicine, 2023
Ustekinumab is a biological therapy that has been approved for treating moderate-to-severe psoriasis. Although injection site reactions, nasopharyngitis, headaches, and infections are the common adverse events associated with ustekinumab, the development
Luyang Kong, Luyang Kong, Dawei Huang, Dawei Huang, Jiajing Lu, Jiajing Lu, Yuexin Zhang, Yuexin Zhang, Ying Li, Ying Li, Xuemei Yi, Xuemei Yi, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source

The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense

BioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo, Olimpio Montero, Nieves Fernandez   +2 more
wiley   +1 more source

Long-term efficacy and safety of guselkumab in Chinese patients with moderate-to-severe plaque psoriasis

Frontiers in Medicine, 2023
BackgroundRandomized controlled trials indicated guselkumab, the first anti-interleukin-23 monoclonal antibody, is efficacious in plaque psoriasis. However, guselkumab's performance in real life is scarcely examined, especially in China.ObjectivesThis ...
Jianfeng Zheng, Jianfeng Zheng, Wenjuan Chen, Wenjuan Chen, Xuemei Yi, Xuemei Yi, Ning Yu, Ning Yu, Yangfeng Ding, Yangfeng Ding, Yunlu Gao, Yunlu Gao   +11 more
doaj   +1 more source

Psoriasis [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. Four decades of clinical and basic research on psoriasis have elucidated many of the pathogenic mechanisms underlying disease and paved the way to effective targeted ...
Paola, Di Meglio, Federica, Villanova, Frank O, Nestle   +2 more
openaire   +2 more sources