Results 11 to 20 of about 258,109 (297)
Cold Spring Harbor Perspectives in Medicine, 2014 Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. Four decades of clinical and basic research on psoriasis have elucidated many of the pathogenic mechanisms underlying disease and paved the way to effective targeted ...
Paola, Di Meglio +2 more
openaire +2 more sources
Canadian Medical Association Journal, 2012 Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis.
Anatoli, Freiman, Benjamin, Barankin
openaire +4 more sources
The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]
, 2013 Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel +12 more
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Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]
, 2014 ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W +6 more
core +2 more sources
Multi-omics integration reveals molecular networks and regulators of psoriasis. [PDF]
, 2019 BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) have been carried out to identify genetic ...
Arneson, Douglas +5 more
core +3 more sources
Viewpoint on handling anti-TNF failure in psoriasis [PDF]
, 2013 An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core +1 more source
European Journal of Inflammation, 2005 A new combination product containing betamethasone dipropionate and calcipotriol (Dovobet® ointment) has been proven very effective and well tolerated in patients with psoriasis vulgaris.
G.A. Vena +37 more
doaj +1 more source
Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]
, 2016 Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo +2 more
core +2 more sources
Journal of the Royal College of Physicians of Edinburgh, 2013 Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting 1.3–2.2% of the UK population.1 Most commonly, psoriasis is characterised by well-demarcated, red plaques with adherent scale with a predilection for the scalp and extensor surfaces of the limbs.
L, Burfield, A D, Burden
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Evaluation of the cutaneous microbiome in psoriasis [PDF]
, 2010 Psoriasis, a highly prevalent disease of humans of unknown cause, is a chronic inflammatory disorder primarily involving skin, with distinctive clinical characteristics.
Alexander Alekseyenko +5 more
core +2 more sources