Results 31 to 40 of about 258,109 (297)

Thrombospondin-1/CD47 interaction regulates Th17 and treg differentiation in psoriasis [PDF]

, 2019
Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studies on the ...
Calzada, María J., Chicharro, Pablo, Cibrian, Danay, Daudén, Esteban, Fuente, Hortensia de la, Jiménez Fernández, María, Llamas Velasco, Mar, Rodriguez Jiménez, Pedro, Sevilla Montero, Javier, Sánchez-Madrid, Francisco, Trigo Torres, Laura, Vara, Alicia   +11 more
core   +2 more sources

Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients

Frontiers in Cell and Developmental Biology, 2022
Background: Psoriasis is a common immune-mediated skin disease that involves T-cell-mediated immunity. Invariant natural killer T (iNKT) cells are a unique lymphocyte subpopulation that share properties and express surface markers of both NK cells and T ...
Yifan Hu, Yifan Hu, Yifan Hu, Youdong Chen, Youdong Chen, Zeyu Chen, Zeyu Chen, Xilin Zhang, Xilin Zhang, ChunYuan Guo, ChunYuan Guo, ZengYang Yu, ZengYang Yu, Peng Xu, Peng Xu, Lei Sun, Lei Sun, Xue Zhou, Xue Zhou, Yu Gong, Yu Gong, Qian Yu, Qian Yu, Yuling Shi, Yuling Shi, Yuling Shi   +25 more
doaj   +1 more source

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +2 more sources

Clinical consequences of antibody formation, serum concentrations, and HLA-Cw6 status in psoriasis patients on Ustekinumab [PDF]

, 2019
Background: Ustekinumab for the treatment of psoriasis is currently administered in a standard dosing regimen. However, some patients tend to benefit from alternative dosing regimens, a step toward personalized medicine.
Busard, Celine, I, Costanzo, Antonio, De Keyser, Eline, Hutten, Barbara A., Lambert, Jo, Lanssens, Sven, Meuleman, Lieve, Spuls, Phyllis, I, van den Reek, Juul M., Zweegers, Jeffrey   +9 more
core   +1 more source

Guidelines for the Diagnosis and Treatment of Psoriasis in China: 2019 Concise Edition#

International Journal of Dermatology and Venerology, 2020
. Psoriasis is an immune-mediated chronic, recurrent, systemic inflammatory disease induced by the combination of hereditary and environmental factors.
Committee of Psoriasis, Dermatology Branch, Chinese Medical Association
doaj   +1 more source

Disseminated eruptive giant mollusca contagiosa in an adult psoriasis patient during efalizumab therapy [PDF]

, 2008
Molluscum contagiosum is a common viral skin infection in children with atopic diathesis and not rare in HIV patients. We report a 45-year-old psoriasis patient who developed eruptive mollusca contagiosa during an antipsoriatic treatment with efalizumab.
Alexander Vasilevic Kuznetsov, Jö, Lim KS, Michael Flaig, Papp KA, Peter Weisenseel, Vozmediano JM, Wachi K   +7 more
core   +1 more source

Positive association between different triglyceride glucose index-related indicators and psoriasis: evidence from NHANES

Frontiers in Immunology, 2023
BackgroundPsoriasis is a chronic inflammatory skin disease with effects that extend beyond the skin. Insulin resistance (IR) has been associated with psoriasis, but it remains unclear how indicators related to the triglyceride glucose (TyG) index, which ...
Dawei Huang, Dawei Huang, Rui Ma, Rui Ma, Xiaoyuan Zhong, Xiaoyuan Zhong, Yuxiong Jiang, Yuxiong Jiang, Jiajing Lu, Jiajing Lu, Ying Li, Ying Li, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source

Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]

, 2013
The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M., Carballido, J.M., Graham, G.J., Jamieson, T., Jaritz, M., King, V., McKimmie, C.S., Nibbs, R.J.B., Pallas, K., Rot, A.   +9 more
core   +1 more source

Long-term efficacy and safety of guselkumab in Chinese patients with moderate-to-severe plaque psoriasis

Frontiers in Medicine, 2023
BackgroundRandomized controlled trials indicated guselkumab, the first anti-interleukin-23 monoclonal antibody, is efficacious in plaque psoriasis. However, guselkumab's performance in real life is scarcely examined, especially in China.ObjectivesThis ...
Jianfeng Zheng, Jianfeng Zheng, Wenjuan Chen, Wenjuan Chen, Xuemei Yi, Xuemei Yi, Ning Yu, Ning Yu, Yangfeng Ding, Yangfeng Ding, Yunlu Gao, Yunlu Gao   +11 more
doaj   +1 more source

Development of bullous pemphigoid during treatment of psoriasis with ustekinumab: a case report and literature review

Frontiers in Medicine, 2023
Ustekinumab is a biological therapy that has been approved for treating moderate-to-severe psoriasis. Although injection site reactions, nasopharyngitis, headaches, and infections are the common adverse events associated with ustekinumab, the development
Luyang Kong, Luyang Kong, Dawei Huang, Dawei Huang, Jiajing Lu, Jiajing Lu, Yuexin Zhang, Yuexin Zhang, Ying Li, Ying Li, Xuemei Yi, Xuemei Yi, Yuling Shi, Yuling Shi   +13 more
doaj   +1 more source