Results 41 to 50 of about 184,542 (286)

Clinical and epidemiologic features of psoriasis patients in an Egyptian medical centerCapsule Summary

JAAD International, 2020
Background: Identification of epidemiologic and phenotypic variations of psoriasis among different ethnic groups can further our understanding of this perplexing disease, aiming at better management of patients worldwide.
Mohamed Hussein Medhat El-Komy, MD, Heba Mashaly, MD, Khadiga S. Sayed, MD, Vanessa Hafez, MD, Marwa S. El-Mesidy, MD, Eman R. Said, MD, Marwa A. Amer, MD, Aya M. AlOrbani, MD, Dina G. Saadi, MD, Mona El-Kalioby, MD, Reem O. Eid, MSc, Yousra Azzazi, MSc, Hagar El Sayed, MD, Nesrin Samir, MD, Marwa R. Salem, MD, Eman D. El Desouky, MD, Hesham Abd El-Moaty Zaher, MD, Hoda Rasheed, MD   +17 more
doaj   +1 more source

Polyethylene Glycol Ointment Alleviates Psoriasis-Like Inflammation Through Down-Regulating the Function of Th17 Cells and MDSCs

Frontiers in Medicine, 2021
Objective: To explore the possible mechanism of improving the imiquimod (IMQ)-induced psoriasis-like inflammation by using polyethylene glycol (PEG) ointment.Methods: We evaluated the appearance of psoriasis lesions by Psoriasis Area and Severity Index ...
Yan Lu, Yan Lu, Yi Xiao, Yi Xiao, Ming-Zhu Yin, Ming-Zhu Yin, Xing-Chen Zhou, Li-Sha Wu, Li-Sha Wu, Wang-Qing Chen, Yan Luo, Yan Luo, Ye-Hong Kuang, Ye-Hong Kuang, Wu Zhu, Wu Zhu   +15 more
doaj   +1 more source

In Vivo Skin 3‐D Surface Reconstruction and Wrinkle Depth Estimation Using Handheld High Resolution Tactile Sensing

Advanced Healthcare Materials, EarlyView.
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha, Arpit Agarwal, Catherine Li, Austin Williams, Dinesh K. Patel, Sankalp Chopkar, Achu Wilson, Ahmet Ozkan, Wenzhen Yuan, Sonal Choudhary, Arash Mostaghimi, Zackory Erickson, Carmel Majidi   +12 more
wiley   +1 more source

The correlation TNF-α gene promoter region -238G, -308G, -857, and -1031 polymorphism with psoriasis vulgaris [PDF]

, 2021
Cashtri Meher, R. Lia Kusumawati Iswara, Irma Damayanti Roesyanto-Mahadi   +2 more
openalex   +1 more source

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source

NOS2-derived low levels of NO drive psoriasis pathogenesis

Cell Death and Disease
Psoriasis is an IL-23/Th17-mediated skin disorder with a strong genetic predisposition. The impact of its susceptibility gene nitric oxide synthase 2 (NOS2) remains unknown.
Ines Köhler, Cecilia Bivik Eding, Nada-Katarina Kasic, Deepti Verma, Charlotta Enerbäck   +4 more
doaj   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

White Sponge Nevus: Report of a Case and Review of the Literature

Acta Medica Iranica, 2017
White sponge nevus is a rare benign autosomal dominant disorder with variable penetrance. It is characterized by asymptomatic white plaques affecting mainly the oral mucosa. Careful clinical and histopathological examination is indicated to exclude other
Mohammadreza Sobhan, Pedram Alirezaei, Mahmood Farshchian, Gholamreza Eshghi, Hamid Reza Ghasemi Basir, Leila Khezrian   +5 more
doaj