Results 41 to 50 of about 293,751 (369)
Frontiers in Pharmacology, 2021 Psoriasis is a chronic inflammatory disease characterized by erythematous scaly plaques, accompanied by systemic damage that leads to the development of multiple comorbidities.
Jiangluyi Cai +11 more
doaj +1 more source
Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. [PDF]
, 2018 IntroductionPsoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of ...
Ahn, Richard +3 more
core +3 more sources
Frontiers in Medicine, 2023 BackgroundRandomized controlled trials indicated guselkumab, the first anti-interleukin-23 monoclonal antibody, is efficacious in plaque psoriasis. However, guselkumab's performance in real life is scarcely examined, especially in China.ObjectivesThis ...
Jianfeng Zheng +11 more
doaj +1 more source
T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action [PDF]
, 2004 Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to ...
Caro, I. +7 more
core +1 more source
The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]
, 2016 BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael +10 more
core +7 more sources
Janus kinase inhibitors in autoimmune bullous diseases
Frontiers in Immunology, 2023 Autoimmune bullous disease (AIBD) is a severe skin disorder caused by autoantibodies that target intercellular or cell-matrix adhesion proteins.
Dawei Huang +9 more
doaj +1 more source
Psoriasis today: experiences of healthcare and impact on quality of life in a major UK cohort [PDF]
, 2015 Aim: To establish how people with psoriasis in the United Kingdom today experience living with their condition including diagnosis, treatment, healthcare provision and impact on daily life.
Gilbert, Annie +4 more
core +1 more source
Frontiers in Medicine, 2021 Objective: To explore the possible mechanism of improving the imiquimod (IMQ)-induced psoriasis-like inflammation by using polyethylene glycol (PEG) ointment.Methods: We evaluated the appearance of psoriasis lesions by Psoriasis Area and Severity Index ...
Yan Lu +15 more
doaj +1 more source
Thrombospondin-1/CD47 interaction regulates Th17 and treg differentiation in psoriasis [PDF]
, 2019 Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studies on the ...
Calzada, María J. +11 more
core +2 more sources
Cold Spring Harbor Perspectives in Medicine, 2014 Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. Four decades of clinical and basic research on psoriasis have elucidated many of the pathogenic mechanisms underlying disease and paved the way to effective targeted ...
Paola, Di Meglio +2 more
openaire +2 more sources