Results 41 to 50 of about 161,729 (326)

Janus kinase inhibitors in autoimmune bullous diseases

open access: yesFrontiers in Immunology, 2023
Autoimmune bullous disease (AIBD) is a severe skin disorder caused by autoantibodies that target intercellular or cell-matrix adhesion proteins.
Dawei Huang   +9 more
doaj   +1 more source

Polyethylene Glycol Ointment Alleviates Psoriasis-Like Inflammation Through Down-Regulating the Function of Th17 Cells and MDSCs

open access: yesFrontiers in Medicine, 2021
Objective: To explore the possible mechanism of improving the imiquimod (IMQ)-induced psoriasis-like inflammation by using polyethylene glycol (PEG) ointment.Methods: We evaluated the appearance of psoriasis lesions by Psoriasis Area and Severity Index ...
Yan Lu   +15 more
doaj   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Diagnosis of Scalp Disorders using Machine Learning and Deep Learning Approach -- A Review [PDF]

open access: yesarXiv, 2023
The morbidity of scalp diseases is minuscule compared to other diseases, but the impact on the patient's life is enormous. It is common for people to experience scalp problems that include Dandruff, Psoriasis, Tinea-Capitis, Alopecia and Atopic-Dermatitis. In accordance with WHO research, approximately 70% of adults have problems with their scalp.
arxiv  

A Hybrid Deep Learning Approach for Diagnosis of the Erythemato-Squamous Disease [PDF]

open access: yes2020 IEEE International Conference on Electronics, Computing and Communication Technologies (CONECCT), 2019
The diagnosis of the Erythemato-squamous disease (ESD) is accepted as a difficult problem in dermatology. ESD is a form of skin disease. It generally causes redness of the skin and also may cause loss of skin. They are generally due to genetic or environmental factors.
arxiv   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

open access: yesFEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He   +5 more
wiley   +1 more source

The optimal use of tildrakizumab in the elderly via improvement of Treg function and its preventive effect of psoriatic arthritis

open access: yesFrontiers in Immunology, 2023
IntroductionAs a form of precision medicine, this study aimed to investigate the specific patient population that would derive the greatest benefit from tildrakizumab, as well as the mechanism of action and efficacy of tildrakizumab in reducing the ...
Takemichi Fukasawa   +13 more
doaj   +1 more source

Pregnancy Outcomes of Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review

open access: yesArthritis Care &Research, EarlyView.
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng   +7 more
wiley   +1 more source

Association Between Metabolic Syndrome and Radiographic Changes in Psoriatic Arthritis: A Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf   +6 more
wiley   +1 more source

Failure of non-cultured melanocyte–keratinocyte transplantation in periungual vitiligo: A case report

open access: yesJournal of Dermatology and Dermatologic Surgery, 2015
Background: Vitiligo is a common pigmentary skin disorder, affecting 0.5–1% of world population. It is one of the psychologically devastating skin disorders, which have different medical and surgical modalities of treatment.
Norah Alsubait   +2 more
doaj   +1 more source

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