Results 81 to 90 of about 272,684 (347)
Advanced Science, EarlyView.m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang +13 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
JAMA dermatology, 2020 Importance The association between psoriasis and risk of cancer remains debatable. Objective To evaluate the association and risk of cancer in patients with psoriasis or psoriatic arthritis, including risk of specific cancer subtypes.
Sofie Vaengebjerg +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu +16 more
wiley +1 more source
Clinical and Translational Medicine, 2022 Background Despite the remarkable breakthroughs achieved in the management of metastatic melanoma using immunotherapy and targeted therapies, long‐term clinical efficacy is often compromised due to dose‐limiting toxicity and innate or acquired resistance.
Guangtong Deng +9 more
doaj +1 more source
International Journal of Molecular Sciences, 2020 Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema. It impairs patients’ quality of life enormously. It has been recognized not only as a skin disease but as a systemic disease, since it also causes arthritis ...
M. Kamata, Y. Tada
semanticscholar +1 more source
Journal of the Royal College of Physicians of Edinburgh, 2013 Psoriasis is a chronic, immune-mediated inflammatory skin disease affecting 1.3–2.2% of the UK population.1 Most commonly, psoriasis is characterised by well-demarcated, red plaques with adherent scale with a predilection for the scalp and extensor surfaces of the limbs.
L, Burfield, A D, Burden
openaire +2 more sources
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Advanced Science, EarlyView.Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai +5 more
wiley +1 more source
Revista Ciencias Biomédicas, 2012 Psoriasis is a disease of the skin that is characterized by the presence of papular andscaly lesions. It is a clinical history of a woman of 38 years old who consulted forclinical manifestations of three days of evolution, consisting of sudden appearance
Von zumbusch psoriasis +1 more
doaj
Annual Review of Immunology, 2014 The skin is the front line of defense against insult and injury and contains many epidermal and immune elements that comprise the skin-associated lymphoid tissue (SALT). The reaction of these components to injury allows an effective cutaneous response to
M. Lowes +2 more
semanticscholar +1 more source