Results 71 to 80 of about 2,361 (179)

Factors influencing HPV vaccine implementation in South Asia: a scoping review protocol

Systematic Reviews
Introduction The HPV vaccine is characterized by its significant effectiveness in preventing the occurrence of cervical cancer. However, the South Asian countries face multiple challenges in implementing the human papillomavirus vaccine (HPV) at scale ...
Priyobrat Rajkhowa, Prachi Pundir, Sherize Merlin Dsouza, Divya Sussana Patil, Prakash Narayanan, Helmut Brand   +5 more
doaj   +1 more source

Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations

Cancer Science, Volume 117, Issue 5, Page 1455-1468, May 2026.
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya, Yoshihiro Otani, Ryo Mizuta, Ryosuke Ikemachi, Mako Kamiura, Joji Ishida, Shinichi Toyooka, Daisuke Ennishi, Shuta Tomida, Shota Tanaka   +9 more
wiley   +1 more source

PSPH promotes colorectal cancer growth by triggering autophagy through AMPK-ULK1 activation and enhancing tumor immune evasion

General physiology and biophysics
Phosphoserine phosphatase (PSPH), a key enzyme in the L-serine synthesis pathway, has been found to promote cancer progression through autophagy modulation. Here, we explored the functional role and molecular mechanisms of PSPH in colorectal cancer (CRC).
Jiajia, Guan, Jie, Ji, Bisheng, Sun, Jun, Fu, Jie, Luo, Bing, Zhu   +5 more
openaire   +2 more sources

Searching for Studies: Development of a Search Strategy for a Systematic Review for Manipal University

Course website for CERTIFICATE COURSE IN EVIDENCE SYNTHESIS: Systematic Review and Meta-analysis for Public Health Evidence South Asia (PHESA) for Department of Health Information, Prasanna School of Public Health (PSPH),Manipal Academy of Higher ...
Carrie Price
core   +8 more sources

PSAT1 Promotes NSCLC Progression via the De Novo Serine Synthesis Pathway and Represents a Therapeutic Vulnerability

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Non‐small cell lung cancer (NSCLC) is a malignant tumor characterized by high morbidity and mortality, as well as metabolic reprogramming. Enhanced serine synthesis plays a crucial role in the aberrant metabolism of NSCLC. Among the three key enzymes involved in serine synthesis, phosphoserine aminotransferase 1 (PSAT1) requires ...
Xijia Zhou, Min Zhao, Yingshu Cao, Xiangyu Zhou, Ke Wang   +4 more
wiley   +1 more source

Two components of the rhpPC operon coordinately regulate the type III secretion system and bacterial fitness in Pseudomonas savastanoi pv. phaseolicola.

PLoS Pathogens, 2019
Many plant bacterial pathogens including Pseudomonas species, utilize the type III secretion system (T3SS) to deliver effector proteins into plant cells.
Kun Li, Yanan Zhu, Wei Yan, Xin Deng, Yanmei Xiao, Liyang Song, Rongxiang Fang, Yantao Jia, Xiaoyan Tang   +8 more
doaj   +1 more source

The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance

MedComm – Oncology, Volume 5, Issue 1, March 2026.
One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang, Guoliang Zhou, Qian Zhang, Shengtao Zhou   +3 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Genome-Wide Linkage and Association Mapping of Halo Blight Resistance in Common Bean to Race 6 of the Globally Important Bacterial Pathogen

Frontiers in Plant Science, 2017
Pseudomonas syringae pv. phaseolicola (Psph) Race 6 is a globally prevalent and broadly virulent bacterial pathogen with devastating impact causing halo blight of common bean (Phaseolus vulgaris L.).
Andrew J. Tock, Andrew J. Tock, Deidré Fourie, Peter G. Walley, Eric B. Holub, Alvaro Soler, Karen A. Cichy, Marcial A. Pastor-Corrales, Qijian Song, Timothy G. Porch, John P. Hart, Renato C. C. Vasconcellos, Joana G. Vicente, Guy C. Barker, Phillip N. Miklas   +14 more
doaj   +1 more source

PSPH Human phosphoserine phosphatase

, 2019
The equilibrium between phosphorylation and dephosphorylation is one of the most important processes that takes place in living cells. Human phosphoserine phosphatase (hPSP) is a key enzyme in the production of serine by the dephosphorylation of phospho ...
Namur Research Institute for Life Sciences, Haufroid, Marie, Namur Institute of Structured Matter, NAmur MEdicine & Drug Innovation Center, Wouters, Johan; id_orcid, Unit of theoretical and structural physico-chemistry, Laboratoire de Chimie Biologique Structurale (CBS), MIRGAUX, Manon, FNRS-FSR, Technological Platform High Performance Computing   +9 more
core   +1 more source