Results 11 to 20 of about 2,026 (172)

The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents. [PDF]

open access: yesJAMA Psychiatry, 2023
This Viewpoint explores how expectations influence outcomes of psychedelic drug therapy.
Colloca L, Nikayin S, Sanacora G.
europepmc   +4 more sources

Novel 3-Cycloaminoindole Compounds as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness, and CNS Disorders. [PDF]

open access: yesACS Med Chem Lett
Provided herein are novel 3-cycloaminoindole compounds as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.
Sabnis RW.
europepmc   +4 more sources

Novel Indole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness, and CNS Disorders. [PDF]

open access: yesACS Med Chem Lett
Provided herein are novel indazole derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders, and processes for preparing such compounds.
Sabnis RW.
europepmc   +8 more sources

Novel Indoline Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness and CNS Disorders. [PDF]

open access: yesACS Med Chem Lett
Provided herein are novel indoline derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.
Sabnis RW, Sabnis AR.
europepmc   +3 more sources

Transformative agents of change and investigative neurotechnologies: A qualitative study of psychedelic technology identities

open access: yesSSM: Qualitative Research in Health, 2023
Clinical and basic science research with psychedelics is a nascent but rapidly growing field. Historically, psychedelics research has faced setbacks due to overenthusiasm, methodological challenges, and conflicting worldviews.
Michaela Barber   +2 more
doaj   +2 more sources

Psychedelic Agents as Potential Therapeutics for Obsessive Compulsive Disorder

open access: yesImpulse: The Premier Undergraduate Neuroscience Journal, 2022
Obsessive-Compulsive Disorder (OCD) is a chronic psychiatric anxiety disorder distinguished by obsessive thoughts and repetitious actions. Current therapies for OCD are not very effective and have many possible side-effects.
Josh Nagra
doaj   +1 more source

Current perspectives on psychedelic treatments in Europe [PDF]

open access: yesThe Lancet Regional Health. Europe
Summary: In this viewpoint, we explore the evolving landscape of psychedelic-assisted therapy in Europe, focusing on clinical, regulatory, and therapeutic developments.
Santiago Madero   +4 more
doaj   +2 more sources

Novel 3-Pyrrolidineindole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis and Mental Illnesses Such as Depression and Post-Traumatic Stress Disorder. [PDF]

open access: yesACS Med Chem Lett
Provided herein are novel 3-pyrrolidineindole derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis and mental illnesses such as depression and post-traumatic stress disorder, and processes for preparing such compounds.
Sabnis RW.
europepmc   +3 more sources

1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI): From an Obscure to Pivotal Member of the DOX Family of Serotonergic Psychedelic Agents - A Review. [PDF]

open access: yesACS Pharmacol Transl Sci
1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI, or DOX where X = -I) was first synthesized in 1973 in a structure-activity study to explore the effect of various aryl substituents on the then newly identified, and subsequently controlled, hallucinogenic agent 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM, or DOX where X = -CH3).
Glennon RA, Dukat M.
europepmc   +3 more sources

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