Results 21 to 30 of about 2,026 (172)

LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain

open access: yesSouth African Medical Journal, 2023
Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic pain often fails to meet the needs
J Van Der Walt, R Parker
doaj   +4 more sources

Novel Psilocin Derivatives as Serotonergic Psychedelic Agents for Treating CNS Disorders

open access: yesACS Medicinal Chemistry Letters
Provided herein are novel psilocin derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating central nervous system (CNS) disorders, and processes for preparing such compounds.
Ram Sabnis
exaly   +4 more sources

The potential of non-psychedelic 5-HT2A agents in the treatment of substance use disorders: a narrative review of the clinical literature

open access: yesExpert Opinion on Pharmacotherapy
Substance use disorders (SUDs) are a public health issue, with only some having FDA-approved indicated treatments and these having high attrition. Consequently, there has been interest in novel interventions (e.g. psychedelics that target 5-HT2A receptors) with some promising results.
Gustavo Angarita, Marc Potenza
exaly   +3 more sources

Therapeutic potential of psychedelic agents [PDF]

open access: yesBritish Journal of Psychiatry, 2015
Amphetamine, methylphenidate, morphine, heroin and ketamine are all drugs that can potentially be used clinically but, whenever we hear the word MDMA, the first thoughts that come to mind are of ecstasy, rave parties and people behaving in an odd manner and experiencing hallucinations, paranoia ...
Nour, MM, Krzanowski, J
openaire   +6 more sources

Infoveillance and Critical Analysis of the Systematically Reviewed Literature on Dimethyltryptamine and the “God Molecule”

open access: yesPharmaceuticals, 2023
Aboriginals of Latin America have used DMT (N,N-dimethyltryptamine) in ritualistic ceremonies for centuries. Nevertheless, there are limited data on web users’ interest concerning DMT.
Ahmed Al-Imam   +4 more
doaj   +1 more source

The Effects of Tryptamine Psychedelics in the Brain: A meta-Analysis of Functional and Review of Molecular Imaging Studies

open access: yesFrontiers in Pharmacology, 2021
There is an increasing interest in the neural effects of psychoactive drugs, in particular tryptamine psychedelics, which has been incremented by the proposal that they have potential therapeutic benefits, based on their molecular mimicry of serotonin ...
João Castelhano   +5 more
doaj   +1 more source

The Therapeutic Potential of Psilocybin

open access: yesMolecules, 2021
The psychedelic effects of some plants and fungi have been known and deliberately exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal source of naturally occurring psychedelics.
Henry Lowe   +7 more
doaj   +1 more source

The bodily self from psychosis to psychedelics

open access: yesScientific Reports, 2023
The sense of self is a foundational element of neurotypical human consciousness. We normally experience the world as embodied agents, with the unified sensation of our selfhood being nested in our body.
Amir Harduf   +4 more
doaj   +1 more source

Case report: Psychedelic-induced seizures captured by intracranial electrocorticography

open access: yesFrontiers in Neurology, 2023
Classic psychedelics are currently re-emerging as therapeutic agents with unique clinical benefits; however, it is also important to recognize the adverse effects of this drug class.
Benjamin N. Blond   +2 more
doaj   +1 more source

Hallucinogenic potential: a review of psychoplastogens for the treatment of opioid use disorder

open access: yesFrontiers in Pharmacology, 2023
The United States is entering its fourth decade of the opioid epidemic with no clear end in sight. At the center of the epidemic is an increase in opioid use disorder (OUD), a complex condition encompassing physical addiction, psychological comorbidities,
Mary G. Hornick, Ashley Stefanski
doaj   +1 more source

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