Results 41 to 50 of about 207,857 (302)

(Es)ketamine as a treatment for depressive episodes with psychotic features: systematic review

BJPsych Open
Background Psychotic symptoms in depression are linked to worse outcomes, and treatment options are limited. Ketamine and esketamine are effective antidepressants, yet most studies have excluded patients with a history of psychotic symptoms.
Henrique Castro Santos, Alexandra Rodrigues, Tiago Machado, Manuel Gonçalves-Pinho, Allan H. Young, Mario F. Juruena   +5 more
doaj   +1 more source

RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons

Molecular Brain, 2021
Anxiety disorders are the most common psychiatric disorders, and the change in the activity of the prefrontal cortex (PFC) is considered as the underlying pathological mechanism. Parvalbumin-expressing (PV+) inhibition contributes to the overall activity
Ying Sun, Le Ma, Jianhua Chen, Weidi Wang, Shiyu Peng, Ying Cheng, Yu Zhang, Jinghong Chen, Peijun Ju   +8 more
doaj   +1 more source

Frequency and Phenotype of Coexisting Aquaporin‐4 and Autoimmune Encephalitis Autoantibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Among 9457 aquaporin‐4 (AQP4) immunoglobulin G‐positive patients, 2071 underwent autoimmune encephalitis antibody testing and 85 (4%) had coexisting antibodies, most commonly cerebrospinal fluid glial fibrillary acidic protein‐IgG and N‐methyl‐D‐aspartate receptor‐IgG, or serum high‐titer GAD65‐IgG.
Laura Cacciaguerra, Binxia Yang, Vanda A. Lennon, Shruti P. Agnihotri, Nusrat Ahsan, Karen S. Fernandez, Erin McLeod, Georgios Mangioris, William R. Meador, Wendy G. Mitchell, Jacqueline A. Nicholas, Amy M. L. Quek, Thomas Shoemaker, Kurt Sieloff, Matt C. Edmond, Rebekah A. Laggis, Kristin L. Flynn, Jessica A. Sagen, Emmanuelle Waubant, John J. Chen, Sarosh R. Irani, Andrew McKeon, Anastasia Zekeridou, Eoin P. Flanagan, Sean J. Pittock, Amy Kunchok   +25 more
wiley   +1 more source

White Matter Measures and Cognition in Schizophrenia

Frontiers in Psychiatry, 2020
White matter (WM) abnormalities are commonly reported in schizophrenia but whether these arise from the axon or myelin compartments or both is not known.
Cemre Erkol, Talia Cohen, Virginie-Anne Chouinard, Virginie-Anne Chouinard, Kathryn Eve Lewandowski, Kathryn Eve Lewandowski, Fei Du, Fei Du, Dost Öngür, Dost Öngür   +9 more
doaj   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Living arrangement modifies the associations of loneliness with adverse health outcomes in older adults: evidence from the CLHLS

BMC Geriatrics, 2022
Background Although it has been suggested that loneliness is a risk factor for adverse health outcomes, living arrangement may confound the association.
Kai Wei, Yong Liu, Junjie Yang, Nannan Gu, Xinyi Cao, Xudong Zhao, Lijuan Jiang, Chunbo Li   +7 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Psychotic-like experiences in non-psychotic help-seekers: Associations with distress, depression and disability

, 2006
Psychotic-like experiences in non-psychotic help-seekers: Associations with distress, depression and ...
SM Cotton (12746624), PD McGorry (10229750), KA Godfrey (15821423), CA Stanford (15821129), Alison Yung (13100928), EJ Killackey (15821420), JA Buckby (15821411), EM Cosgrave (15821417)   +7 more
core   +1 more source

Adolescent self-control predicts midlife hallucinatory experiences: 40-year follow-up of a national birth cohort. [PDF]

, 2014
Associations between self-control in adolescence and adult mental health are unclear in the general population; to our knowledge, no study has investigated self-control in relation to psychotic-like ...
Richards, M, Barnett, Jenifer, Croudace, T, Jones, PB, Jones, Peter B., Richards, Marcus, Nishida, A, Nishida, Atsushi, Xu, Kate Man, Xu, KM, Croudace, Tim; id_orcid, Barnett, J   +11 more
core   +1 more source