Results 111 to 120 of about 3,223,608 (377)

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

Identifying psychosis episodes in psychiatric admission notes via rule-based methods, machine learning, and pre-trained language models

Translational Psychiatry
Early and accurate diagnosis is crucial for effective treatment and improved outcomes, yet identifying psychotic episodes presents significant challenges due to its complex nature and the varied presentation of symptoms among individuals.
Yining Hua, Suzanne V. Blackley, Ann K. Shinn, Joseph P. Skinner, Lauren V. Moran, Li Zhou   +5 more
doaj   +1 more source

Near-Infrared Stimulation in Psychiatry Disorders: A Systematic Review of Efficacy and Biological Mechanisms

NeuroSci
Background: Photobiomodulation (PBM), also referred to as low-level light therapy (LLLT), is an emerging non-pharmacological approach. This treatment is considered low-risk, cost-effective, and non-invasive, utilizing near-infrared light (NIR).
Joanna Woźniak, Michał Pazdrak, Ada Domanasiewicz, Jakub Kaźmierski   +3 more
doaj   +1 more source

Aberrant functional connectivity between the amygdala and the temporal pole in drug-free generalized anxiety disorder

Frontiers in Human Neuroscience, 2016
The amygdala and the dorsolateral prefrontal cortex (DLPFC) play important roles in emotion dysregulation, which has a profound impact on etiologic research of generalized anxiety disorder (GAD).
Wei Li, Huiru Cui, Zhipei Zhu, Li Kong, Qian Guo, Yikang Zhu, Qiang Hu, Lanlan Zhang, Hui Li, Qingwei Li, Jiangling Jiang, Jordan Meyers, Jianqi Li, Jijun Wang, Jijun Wang, Jijun Wang, Zhi Yang, Chunbo Li, Chunbo Li, Chunbo Li   +19 more
doaj   +1 more source

Parenthood patterns used by parents of psychotic patients [PDF]

Background Most of the psychotic patients have problems in their relationship with their own parents, and often parents begin the impaired relationship.
قمری گیوی, حسین, مولوی, پرویز, کریم اللهی, منصوره   +2 more
core  

Are cannabis-using and non-using patients different groups? Towards understanding the neurobiology of cannabis use in psychotic disorders

Journal of Psychopharmacology, 2018
A substantial body of credible evidence has accumulated that suggest that cannabis use is an important potentially preventable risk factor for the development of psychotic illness and its worse prognosis following the onset of psychosis.
M. Sami, S. Bhattacharyya
semanticscholar   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra, Tin‐Suet Joan Lee, Jacob Vorstman, Patricia Parkin, Louise Gallagher, Aneta Krakowski   +5 more
wiley   +1 more source

Stage-dependent patterns of cognitive network connectivity in early psychosis

Nature Communications
Cognitive impairments in early psychosis are common, yet prior studies have focused mainly on domain-specific deficits rather than inter-domain relationships.
XiaoChen Tang, YanYan Wei, JiaoYan Pang, LiHua Xu, HuiRu Cui, MingLiang Ju, HaiChun Liu, Qiang Hu, LingYun Zeng, YingYing Tang, ZhengHui Yi, ChunBo Li, JiJun Wang, TianHong Zhang   +13 more
doaj   +1 more source

Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice

Molecular Brain, 2017
Studies have implied that the circadian oscillation of mitogen-activated protein kinase (MAPK) signal pathways is crucial for hippocampus-dependent memory.
Lei Chen, Tatiana Serdyuk, Beimeng Yang, Shuai Wang, Shiqing Chen, Xixia Chu, Xu Zhang, Jinjing Song, Hechen Bao, Chengbin Zhou, Xiang Wang, Shuangle Dong, Lulu Song, Fujun Chen, Guang He, Lin He, Ying Zhou, Weidong Li   +17 more
doaj   +1 more source

Two Novel Loci of RELN Associated With Antipsychotics Response in Chinese Han Population

Frontiers in Pharmacology, 2020
BackgroundThere are great individual differences in the drug responses; however, there are few prognostic drug response biomarkers available. RELN is one of the more extensively examined schizophrenia candidate genes.
Qingqing Xu, Mo Li, Shengying Qin, Yaojing Li, Ailing Ning, Yingmei Fu, Dongxiang Wang, Duan Zeng, Huafang Li, Huafang Li, Wenjuan Yu, Shunying Yu   +11 more
doaj   +1 more source