Results 121 to 130 of about 3,094,120 (388)

Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the effect of a potent cytochrome P450 (CYP) 3A inhibitor and CYP inducer on the pharmacokinetics of ritlecitinib, a JAK3/TEC family kinase inhibitor, and assess the effect of ritlecitinib on the pharmacokinetics of CYP substrates (midazolam, efavirenz, tolbutamide, caffeine and oral contraceptives [ethinyl oestradiol and levonorgestrel])
Vivek S. Purohit, Yeamin Huh, Martin E. Dowty, Anna Plotka, Alexandre Lejeune, Hindu Kalluru, Brian Hee   +6 more
wiley   +1 more source

Genetic analysis for two italian siblings with usher syndrome and schizophrenia. [PDF]

, 2012
Usher syndrome is a group of autosomal recessive genetic disorders characterized by deafness, retinitis pigmentosa, and sometimes vestibular areflexia.
Article Id, Daniela Domanico, Enzo Maria Vingolo, Marcella Nebbioso, Paolo Trabucco, Serena Fragiotta   +5 more
core   +3 more sources

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

The Malingering of Psychotic Disorders

Jefferson Journal of Psychiatry, 2000
The phenomenon if malingered psychosis is examined through a review if the available literature. Possible motivations fi r malingering are discussed, and clinical indicators if'feigned psychotic symptoms are reviewed. The methods discussed ficus on the inpatient evaluation if suspected malingerers and include discussions if interview techniques and ...
R Michael, Harris
openaire   +3 more sources

Unveiling Circular Economy Pathways Among Small and Medium Hotels Through a Hybrid Analytical Framework

Business Strategy and the Environment, EarlyView.
ABSTRACT Small and medium‐sized hotels (SME hotels), which constitute the majority of the global hospitality sector, face mounting pressure to align with sustainability goals. However, their transition to circular economy (CE) practices remains under‐theorised and poorly implemented, particularly in emerging economies where institutional fragility and ...
Sandeep Kumar Dey, Reshma Sandeep Kumar Dey, Sinh Duc Hoang, Jose Arturo Garza‐Reyes   +3 more
wiley   +1 more source

Dynamic Functional Connectivity Within the Fronto-Limbic Network Induced by Intermittent Theta-Burst Stimulation: A Pilot Study

Frontiers in Neuroscience, 2019
PurposeThe utility of transcranial magnetic stimulation (TMS) has been growing rapidly in both neurocognitive studies and clinical applications in decades.
Yingying Tang, Yingying Tang, Xiong Jiao, Xiong Jiao, Junjie Wang, Junjie Wang, Tianyuan Zhu, Jie Zhou, Jie Zhou, Zhenying Qian, Tianhong Zhang, Huiru Cui, Hui Li, Xiaochen Tang, Lihua Xu, Ling Zhang, Yanyan Wei, Jianhua Sheng, Liu Liu, Jijun Wang, Jijun Wang, Jijun Wang   +21 more
doaj   +1 more source

Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits

JAMA psychiatry, 2019
Key Points Question Is the genetic liability to psychotic experiences shared with schizophrenia and/or other neuropsychiatric disorders and traits?
S. Legge, H. Jones, K. Kendall, A. Pardiñas, G. Menzies, Matthew Bracher-Smith, V. Escott-Price, E. Rees, K. Davis, M. Hotopf, J. Savage, D. Posthuma, P. Holmans, G. Kirov, M. Owen, M. O’Donovan, S. Zammit, J. Walters   +17 more
semanticscholar   +1 more source

Under‐Interpretation of Neuroimaging Data in Insanity Assessment: A Hidden Risk

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Neuroimaging data can provide valuable insights into insanity evaluations, but the debate over its use for legal purposes is far from resolved. While much attention has been given to the risks of over‐interpretation, potential errors stemming from under‐interpretation received less scrutiny. In this paper, we aim to showcase how this error may
Camilla Frangi, Alexa Schincariol, Pietro Pietrini, Giuseppe Sartori, Stefano Ferracuti, Cristina Scarpazza   +5 more
wiley   +1 more source

PSYCHOSIS AND DEPRESSION – A NEUROBIOLOGICAL VIEW [PDF]

, 2009
Psychosis and depression are syndromes that affect the most basic human processes of perception and judgment. Traditional dichotomous classification of psychotic and affective disorders resolved in strict separation between schizophrenia on one hand and ...
Peter Pregelj
core   +1 more source

Pathways between childhood victimization and psychosis-like symptoms in the ALSPAC Birth Cohort [PDF]

, 2012
Background: Several large population-based studies have demonstrated associations between adverse childhood experiences and later development of psychotic symptoms.
A. Schreier, Allen, B. Maughan, Bowen, Cohen, D. Wolke, Fisher, Fisher, Fisher, Freeman, G. Lewis, Garety, Goodman, Goodman, Gracie, H. L. Fisher, Hardy, Horwood, Hughes, Johnsona, Kelleher, Krabbendam, M. R. Munafo, Morgan, Read, Reijntjes, S. Zammit, Schreier, Shaffer, Sidebotham, Thewissen, Thomas, van Os, Wigman, Wolke, Wolke, Zammit   +36 more
core   +1 more source