Results 91 to 100 of about 50,737 (331)

Association between functional recovery and medication adherence in schizophrenia

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 510-515, December 2022., 2022
Abstract Aim Medication adherence is important for achieving functional recovery from schizophrenia and is commonly assessed using the Drug Attitude Inventory‐30 (DAI‐30). Subscales of the DAI‐30, including “awareness of the need for medication,” “awareness of the effects of psychiatric drugs,” and “impression of medication,” have been used to assess ...
Junpei Ishii, Fumitoshi Kodaka, Hisatsugu Miyata, Wataru Yamadera, Hikaru Seto, Hidejiro Higuchi, Yoshiaki Tsuruoka, Masahiro Shigeta   +7 more
wiley   +1 more source

Efficacy of transcranial direct current stimulation for improving postoperative quality of recovery in elderly patients undergoing lower limb major arthroplasty: a randomized controlled substudy

Frontiers in Neurology
BackgroundPrevious studies have demonstrated improvements in motor, behavioral, and emotional areas following transcranial direct current stimulation (tDCS), but no published studies have reported the efficacy of tDCS on postoperative recovery quality in
Mingshu Tao, Mingshu Tao, Jie Yang, Jie Yang, Rongguang Liu, Rongguang Liu, Song Zhang, Yuan Han, Chunyan Li, Chunyan Li, Qi Wei, Qi Wei, Dexian Chen, Dexian Chen, Jiaxing Fang, Jiaxing Fang, Hongxing Zhang, Yuwei Wang, He Liu, He Liu, He Liu, He Liu, Jun-Li Cao, Jun-Li Cao   +23 more
doaj   +1 more source

UHPLC‐QTOFMS Urine Drug Screening With Dilute‐and‐Shoot Sample Preparation and Vacuum‐Insulated Probe‐Heated Electrospray Ionization

Drug Testing and Analysis, EarlyView.
The new ionization technique, vacuum‐insulated probe‐heated electrospray, allows for a simple dilute‐and‐shoot sample preparation to be used with liquid chromatography time‐of‐flight mass spectrometry in urine drug screening. Comparison with a method relying on solid‐phase extraction and conventional electrospray ionization shows improved performance ...
Mira Sundström, Pirkko Kriikku, Ilkka Ojanperä, Carsten Baessmann, Anna Pelander   +4 more
wiley   +1 more source

A reliable quantitative method for determining CBD content and release from transdermal patches in Franz cells

Phytochemical Analysis, Volume 33, Issue 8, Page 1257-1265, December 2022., 2022
Abstract Introduction There are several cannabidiol (CBD) transdermal patches available on the market. However, none are FDA‐approved. Furthermore, not much evidence has been published about CBD release and skin permeation from such patches, so the effectiveness and reliability remain unclear. Objectives We aimed to develop a method to determine the in
Liyun Yu, Frederikke Bahrt Madsen, Sofie Helvig Eriksen, Aaron J. C. Andersen, Anne Ladegaard Skov   +4 more
wiley   +1 more source

Drug Recommendation toward Safe Polypharmacy [PDF]

arXiv, 2018
Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug recommendation problems when multiple drugs have been taken simultaneously.
arxiv  

Studies on the Stability and Microbial Biotransformation of Five Deschloroketamine Derivatives as Prerequisite for Wastewater‐Based Epidemiology Screening

Drug Testing and Analysis, EarlyView.
Microbial biotransformation and stability of deschloroketamine derivatives and their metabolites in WW by incubating parent compounds, rat urine, or rat feces showed that deschloroketamine parents and Phase I metabolite were still detectable and that Phase II metabolites decreased in peak areas.
Fabian Frankenfeld, Lea Wagmann, Markus R. Meyer   +2 more
wiley   +1 more source

On the Way to More Convenient Description of Drug-Plasma Protein Binding [PDF]

arXiv, 2012
The theoretical case is considered where the total amount of plasma protein is conserved, but the drug is eliminated after its single application. After a single drug application at time t = 0, the total drug concentration is measured at times ti,...,tk and the total drug concentration at time ti is denoted by {\phi}i.
arxiv  

On the metapharmacology of psychotropic drugs

Comprehensive Psychiatry, 1965
Summary We have proposed psychoanalytic metapsychology as a useful explanatory tool for investigation of drug effects upon the psychic apparatus. All six metapsychological points of view: (1) genetic; (2) dynamic; (3) topographic; (4) structural; (5) economic; (6) adaptive, were brought to bear upon the psychic events in connection with drug use ...
Roy M. Whitman, Paul H. Ornstein
openaire   +3 more sources

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

Drug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer, Maria Carmela Emanuele, Brianna N. Stang, Katleen Van Uytfanghe, Jessica Masson, Xavier Bouvot, Catherine Lamoureux, Alessandro Proposito, Fabiano Reniero, Margaret V. Holland, Alex J. Krotulski, Luisa Mannina, Christophe P. Stove, Claude Guillou   +13 more
wiley   +1 more source

Pharmacokinetics, safety of a single dose and multiple doses of voriconazole injection of two formulations, in Chinese healthy volunteers

Precision Medical Sciences, Volume 11, Issue 4, Page 186-194, December 2022., 2022
Voriconazole injection of Hailing Pharmaceutical Group has achieved a breakthrough in improving the solubility of voriconazole with different excipients for the first time in China. We evaluated the pharmacokinetics (PK) and safety of single/multiple doses of voriconazole injection of Hailing Pharmaceutical Group (Test, T), a biosimilar to Vfend ...
Chunqi Huang, Yannan Wang, Yi Wu, Sisi Lin, Rui Hao, Jin Yu, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Hui Huang, Zhuoyan Wang, Ying Wang   +15 more
wiley   +1 more source