Results 21 to 30 of about 50,737 (331)
Free acquisition of psychotropic drugs by the Brazilian adult population and presence on the National List of Essential Medicines [PDF]
The aims of the present study were to estimate the free-of-charge acquisition of psychotropic drugs among Brazilian adults; analyze the distribution of psychotropics according to their presence on the Relação Nacional de Medicamentos Essenciais (RENAME ...
Patrícia Silveira Rodrigues+3 more
doaj +1 more source
Our study analyzed 152 samples of alcoholic beverages collected from the states of São Paulo and Minas Gerais, Brazil, using gas chromatography with flame ionization detection (GC-FID) and mass spectrometry (GC-MS), Fourier transform infrared ...
Giuseppina Negri+2 more
doaj +1 more source
Analise Demografica e Socioeconomica do Uso e do Acesso a Medicamentos Antidepressivos no Brasil [PDF]
Depressive disorders, in addition to causing direct negative impacts on health, are also responsible for imposing substantial costs on society. In relation to the treatment of depression, antidepressants have proven effective, and, to the World Health Organization, access to psychotropic drugs for people with mental illnesses offers a chance of ...
arxiv
Drug Selection via Joint Push and Learning to Rank [PDF]
Selecting the right drugs for the right patients is a primary goal of precision medicine. In this manuscript, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to accurately predicting 1). the ranking positions of sensitive drugs and 2).
arxiv +1 more source
Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]
Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv
Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD.
Xiao-Yu Sun+7 more
doaj
AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv
Colorectal cancer (CRC) is a type of malignant tumor that seriously threatens human health and life, and its treatment has always been a difficulty and hotspot in research.
Haowei Liu+5 more
doaj
In older adults who experienced the death of a partner, higher prolonged grief symptoms were associated with less anticorrelation between retrosplenial default network and cingulo‐opercular networks during resting state, and more dwell time in a dynamic functional connectivity state involving positive correlations between large‐scale brain networks ...
Saren H. Seeley+3 more
wiley +1 more source
NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]
Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv