The Slack Channel Deletion Causes Mechanical Pain Hypersensitivity in Mice
The role of the Slack (also known as Slo2.2, KNa1.1, or KCNT1) channel in pain-sensing is still in debate on which kind of pain it regulates. In the present study, we found that the Slack–/– mice exhibited decreased mechanical pain threshold but normal ...
Ye Liu+34 more
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Do antidepressants cure or create abnormal brain states? [PDF]
Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley+55 more
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The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae+6 more
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Unintentional drowning : Role of medicinal drugs and alcohol [PDF]
Background: Alcohol is a well-known risk factor in unintentional drownings. Whereas psychotropic drugs, like alcohol, may cause psychomotor impairment and affect cognition, no detailed studies have focused on their association with drowning.
Lillsunde, Pirjo+5 more
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Robust sex difference among humans regarding psychiatry- and pain-related behaviors is being researched; however, the use of female mice in preclinical research is relatively rare due to an unchecked potential behavioral variation over the estrous cycle.
Weinan Zhao+83 more
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Титульные страницы и содержание [PDF]
BACKGROUND: Psychotropic drugs are prescribed to approximately 30-40% of adults with intellectual disability (ID) and challenging behaviour, despite the limited evidence of effectiveness and the potential of adverse events. AIMS: To assess the prevalence
Egberts, Toine C G+5 more
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Reducing psychotropic drug use in nursing homes in Belgium : an implementation study for the roll-out of a practice improvement initiative [PDF]
Background and Objective: Psychotropic drug use is high in nursing homes in Belgium. A practice improvement initiative (including education, professional support and the transition towards person-centred care) achieved significant reductions in ...
Christiaens, Thierry+5 more
core +1 more source
Psychotropic medication use and cognition in institutionalized older adults with mild to moderate dementia [PDF]
Background: Most studies examining psychotropic medication use on cognition in older persons with dementia include measures of global cognitive function.
Alexopoulos+16 more
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Doctor or drug dealer? International legal provisions for the legitimate handling of drugs of abuse [PDF]
© The Author(s) 2020. The final, definitive version of this paper has been published in: Gallagher, C. T., Atik, S. K., Isse, L., & Mann, S. K. (2020). Doctor or drug dealer?
Atik, Sanaa+3 more
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Incidence and drug treatment of emotional distress after cancer diagnosis : a matched primary care case-control study [PDF]
Notes This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License.Peer ...
A J Lee+33 more
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