Results 21 to 30 of about 107,636 (348)

Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. [PDF]

, 2014
Small molecules that increase the presynaptic function of aminergic cells may provide neuroprotection in Parkinson's disease (PD) as well as treatments for attention deficit hyperactivity disorder (ADHD) and depression.
Biedermann, T, Chou, M-T, Djapri, C, Hadi, R, Huang, B, Jang, J, Krantz, DE, Lam, HA, Lawal, HO, Lawless, GM, Maidment, NT, Roberts, L, Shahi, V, Terrell, A   +13 more
core   +2 more sources

Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats

Neurobiology of Stress, 2022
Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain.
Ning-Ning Ji, Qing-Xiang Meng, Ying Wang, Zi-Ming Zhou, Yu Song, Rong Hua, Yong-Mei Zhang   +6 more
doaj   +1 more source

Protocol to study projection-specific circuits in the basal ganglia of adult mice using viral vector tracing, optogenetics, and patch-clamp technique

STAR Protocols, 2023
Summary: Analysis of synaptic strength and plasticity provides functional insights of complicated neural circuits. Here, we describe steps for cell- and projection-specific optogenetic manipulation of divergent basal ganglia circuits using anterograde ...
Ya-Wei Ji, Xiang-Ying Xu, Cui Yin, Chunyi Zhou, Cheng Xiao   +4 more
doaj   +1 more source

Current Concepts on Drug Abuse and Dependence [PDF]

, 2015
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza, Bălălău, Cristian, Ciobanu, Anne-Marie, Cobani, Oana Denisa, Negrei, Carolina, Vlăsceanu, Ana Maria   +5 more
core   +3 more sources

Chemical Analysis of Suspected Unrecorded Alcoholic Beverages from the States of São Paulo and Minas Gerais, Brazil

Journal of Analytical Methods in Chemistry, 2015
Our study analyzed 152 samples of alcoholic beverages collected from the states of São Paulo and Minas Gerais, Brazil, using gas chromatography with flame ionization detection (GC-FID) and mass spectrometry (GC-MS), Fourier transform infrared ...
Giuseppina Negri, Julino Assunção Rodrigues Soares Neto, Elisaldo Luiz de Araujo Carlini   +2 more
doaj   +1 more source

Initiation of Psychotropic Medication after Partner Bereavement: A Matched Cohort Study [PDF]

, 2013
Background Recent changes to diagnostic criteria for depression in DSM-5 remove the bereavement exclusion, allowing earlier diagnosis following bereavement.
A Bourke, AL Forte, Christina R. Victor, Derek G. Cook, DM Fick, DS Davydow, E Bui, EL Fosbøl, G Brown, Iain M. Carey, J Glass, J Möller, J Warner, James Coyne, JC Wakefield, JD Lewis, JM Cook, M Stroebe, ME Charlson, R Mojtabai, S Zisook, S Zisook, SM Shah, SM Shah, SM Shah, Stephen DeWilde, Sunil M. Shah, Tess Harris   +27 more
core   +3 more sources

Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection

Angewandte Chemie, EarlyView.
In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González, Eva Garrido, Estela Climent, Cristian Vicent, Ramón Martínez‐Máñez, Vicente Martí‐Centelles   +5 more
wiley   +2 more sources

Psychotropic drugs [PDF]

BMJ, 1967
  +9 more sources

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Frontiers in Aging Neuroscience, 2022
Recent observation demonstrated that prolonged anesthesia modifies brain synaptic architecture in all ages, including adult. Propofol is the most commonly utilized anesthetics at clinic.
Xiaoxuan Yang, Chen Chen, Chen Chen, Dongmei Qu, Yanping Liu, Yanping Liu, Ning Wang, Ning Wang, Haibi Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Yuqing Wu, Han Lu   +16 more
doaj   +1 more source

The Prevalence of Psychotropic Drugs and Relevant Factors in Iranian Youth: A Systematic Review and Meta-Analysis [PDF]

Addiction and Health, 2021
Background: Psychotropic drugs can cause many complications and side effects including cognitive, behavioral, and psychological disorders. In recent years, the Iranian youth and adolescents have growingly been using psychotropic drugs.
Ahmad Ali Eslami, Sedigheh Shariatinia, Mohadeseh Khoshgoftar   +2 more
doaj   +1 more source