Results 81 to 90 of about 107,636 (348)

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

Drug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner, Hannah Rämisch, Laura Besch, Johannes Schmeinck, Uwe Karst   +4 more
wiley   +1 more source

Socioeconomic determinants of psychotropic drug utilisation among elderly: a national population-based cross-sectional study

BMC Public Health, 2010
Background Psychotropic drugs are commonly utilised among the elderly. This study aimed to analyse whether two socioeconomic determinants - income and marital status - are associated with differences in utilisation of psychotropic drugs and potentially ...
Petzold Max, Andersson Karolina, Lesén Eva, Carlsten Anders   +3 more
doaj   +1 more source

How did the use of psychotropic drugs change during the Great Recession in Portugal? A follow-up to the National Mental Health Survey

BMC Psychiatry, 2020
Background Research suggests that economic recessions might be associated with a higher use of psychotropic drugs, but literature is scarce and contradictory in identifying the most vulnerable groups. This study aims to assess possible changes in the use
Manuela Silva, Ana Antunes, Sofia Azeredo-Lopes, Graça Cardoso, Miguel Xavier, Benedetto Saraceno, José Miguel Caldas-de-Almeida   +6 more
doaj   +1 more source

Non-conviction based sanctions:the Court of Justice v. the European Court of Human Rights, who decides? [PDF]

, 2011
Recovering the proceeds of crime has become an instrumental tool in the fight against transnational criminality. It is expounded frequently that this tool is fundamental because it removes the incentive and means to commit further criminal activity ...
Egan, Maureen
core   +3 more sources

Simulation of the Metabolism of New Psychoactive Substances Using Electrochemistry‐Mass Spectrometry: Introducing an Innovative Software Tool for Rapid Data Evaluation

Drug Testing and Analysis, EarlyView.
A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner, Steffen Heuckeroth, Michael Pütz, Uwe Karst   +3 more
wiley   +1 more source

Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel

Nature Communications
Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. Here, we describe an unrecognized role for the lysosome, showing that it finely controls macrophage inflammatory function by manipulating
Yanhong Xing, Meng-meng Wang, Feifei Zhang, Tianli Xin, Xinyan Wang, Rong Chen, Zhongheng Sui, Yawei Dong, Dongxue Xu, Xingyu Qian, Qixia Lu, Qingqing Li, Weijie Cai, Meiqin Hu, Yuqing Wang, Jun-li Cao, Derong Cui, Jiansong Qi, Wuyang Wang   +18 more
doaj   +1 more source

Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors

Frontiers in Pharmacology
IntroductionThe paraventricular thalamic nucleus (PVT) is recognized for its critical role in pain regulation, yet the precise molecular mechanisms involved remain poorly understood. Here, we demonstrated an essential role of the microglial adenosine A2A
Yiping Cao, Yiping Cao, Yiping Cao, Zhou Wu, Zhou Wu, Zhou Wu, Moruo Zhang, Moruo Zhang, Moruo Zhang, Ran Ji, Ran Ji, Ran Ji, Hongxing Zhang, Hongxing Zhang, Hongxing Zhang, Lingzhen Song, Lingzhen Song, Lingzhen Song   +17 more
doaj   +1 more source

Prescribing pattern of psychotropic drugs used in non-psychiatric patients among outpatient department of two teaching hospitals in Bangladesh

Bangladesh Journal of Pharmacology, 2015
The objectives were to evaluate the prevalence, pattern and rational of psychotropic drugs prescribing by general physicians in two teaching hospitals in Bangladesh in non-psychiatric patient.
Nazmun Nahar Alam, Ferdous Ara, Md. Jalal Uddin Iqbal   +2 more
doaj   +1 more source

Pregabalin: a range of misuse-related unanswered questions [PDF]

, 2019
© 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
core   +2 more sources

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB‐5′Br‐PINACA, in Seized Herbal Materials

Drug Testing and Analysis, EarlyView.
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi, Lucas André Zeoly, Rafael Lanaro, Ingrid Simões Oliveira, Mariana Cepollaro Diana, Mauricio Yonamine, Jose Luiz Costa   +6 more
wiley   +1 more source