Discrimination of psychrophilic enzymes using machine learning algorithms with amino acid composition descriptor [PDF]
Frontiers in Microbiology, 2023 IntroductionPsychrophilic enzymes are a class of macromolecules with high catalytic activity at low temperatures. Cold-active enzymes possessing eco-friendly and cost-effective properties, are of huge potential application in detergent, textiles ...
Ailan Huang +4 more
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Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 [PDF]
Journal of Fungi, 2021 Psychrophilic organisms possess several adaptive strategies which allow them to sustain life at low temperatures between −20 to 20 °C. Studies on Antarctic psychrophiles are interesting due to the multiple stressors that exist on the permanently cold ...
Nur Athirah Yusof +2 more
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Psychrophilic Enzymes: From Folding to Function and Biotechnology [PDF]
Scientifica, 2013 Psychrophiles thriving permanently at near-zero temperatures synthesize cold-active enzymes to sustain their cell cycle. Genome sequences, proteomic, and transcriptomic studies suggest various adaptive features to maintain adequate translation and proper
Georges Feller
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Some Clues about Enzymes from Psychrophilic Microorganisms
Microorganisms, 2022 Enzymes purified from psychrophilic microorganisms prove to be efficient catalysts at low temperatures and possess a great potential for biotechnological applications.
Roberta Rapuano, Giuseppe Graziano
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Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli [PDF]
Advanced ScienceOrthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion.
Nikolaj G. Koch +4 more
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Computational and Structural Biotechnology Journal, 2021 CCA-adding enzymes are highly specific RNA polymerases that add and maintain the sequence C-C-A at tRNA 3‘-ends. Recently, we could reveal that cold adaptation of such a polymerase is not only achieved at the expense of enzyme stability, but also at the ...
Raphaël de Wijn +6 more
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Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles [PDF]
Nature CommunicationsProtein diffusion, critical for cellular metabolism, occurs in the highly crowded cytoplasm. Understanding how this dynamics changes when organisms are adapted to different thermal niches is a fundamental challenge in microbiology and biophysics.
Beatrice Caviglia +8 more
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Network reorganization of a cold-adapted β-glucosidase couples conformational flexibility to catalytic efficiency under low-temperature conditions [PDF]
Frontiers in MicrobiologyIntroductionElucidating how cold-active enzymes maintain efficient catalysis under low-temperature conditions remains a significant question in enzymology.
Xian He +20 more
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Genomics and ecology of Epibryaceae, a psychrophilic family in Chaetothyriales [PDF]
IMA FungusThe family Epibryaceae is one of the early-diverging lineages within the order Chaetothyriales. Available molecular data show that most species are associated with mosses, liverworts, and lichens, typically inhabiting apparently psychrophilic ...
Bruno Paulo Rodrigues Lustosa +15 more
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Towards Rational Computational Engineering of Psychrophilic Enzymes [PDF]
Scientific Reports, 2019 Geir V Isaksen +2 more
exaly +2 more sources