Discrimination of psychrophilic enzymes using machine learning algorithms with amino acid composition descriptor [PDF]
Frontiers in Microbiology, 2023 IntroductionPsychrophilic enzymes are a class of macromolecules with high catalytic activity at low temperatures. Cold-active enzymes possessing eco-friendly and cost-effective properties, are of huge potential application in detergent, textiles ...
Fuping Lu, Fufeng Liu, Lu Fuping
exaly +4 more sources
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 [PDF]
Journal of Fungi, 2021 Psychrophilic organisms possess several adaptive strategies which allow them to sustain life at low temperatures between −20 to 20 °C. Studies on Antarctic psychrophiles are interesting due to the multiple stressors that exist on the permanently cold ...
Nur Athirah Yusof +2 more
doaj +2 more sources
Psychrophilic Enzymes: From Folding to Function and Biotechnology [PDF]
Scientifica, 2013 Psychrophiles thriving permanently at near-zero temperatures synthesize cold-active enzymes to sustain their cell cycle. Genome sequences, proteomic, and transcriptomic studies suggest various adaptive features to maintain adequate translation and proper
Georges Feller
doaj +2 more sources
Some Clues about Enzymes from Psychrophilic Microorganisms
Microorganisms, 2022 Enzymes purified from psychrophilic microorganisms prove to be efficient catalysts at low temperatures and possess a great potential for biotechnological applications.
Giuseppe Graziano, Graziano Giuseppe
exaly +3 more sources
Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles [PDF]
Nature CommunicationsProtein diffusion, critical for cellular metabolism, occurs in the highly crowded cytoplasm. Understanding how this dynamics changes when organisms are adapted to different thermal niches is a fundamental challenge in microbiology and biophysics.
Beatrice Caviglia +8 more
doaj +2 more sources
Characterisation of a cold-adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS-131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation. [PDF]
FEBS JWe investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Yato A +10 more
europepmc +2 more sources
Cold-Active Starch-Degrading Enzymes from a Cold and Alkaline Greenland Environment: Role of Ca2+ Ions and Conformational Dynamics in Psychrophilicity [PDF]
BiomoleculesCold-active enzymes hold promise for energy-efficient processes. Amylases are widely used in household and industrial applications, but only a few are cold-active.
Malthe Kjær Bendtsen +16 more
doaj +2 more sources
Genomics and ecology of Epibryaceae, a psychrophilic family in Chaetothyriales [PDF]
IMA FungusThe family Epibryaceae is one of the early-diverging lineages within the order Chaetothyriales. Available molecular data show that most species are associated with mosses, liverworts, and lichens, typically inhabiting apparently psychrophilic ...
Bruno Paulo Rodrigues Lustosa +15 more
doaj +4 more sources
Mechanistic insights into a cold-adapted glucokinase with high thermal stability were revealed by site-directed spin labeling ESR [PDF]
Biophysics and PhysicobiologyThe structural flexibility of enzymes plays an essential role in determining their catalytic efficiency and thermal stability. Cold-adapted enzymes are typically highly flexible, resulting in high catalytic activity but low stability.
Akane Yato, Masaki Horitani
doaj +2 more sources
Towards Rational Computational Engineering of Psychrophilic Enzymes [PDF]
Scientific Reports, 2019 Geir Villy Isaksen +2 more
exaly +2 more sources