Results 21 to 30 of about 532,623 (184)

Optimization to low temperature activity in psychrophilic enzymes. [PDF]

Int J Mol Sci, 2012
Psychrophiles, i.e., organisms thriving permanently at near-zero temperatures, synthesize cold-active enzymes to sustain their cell cycle. These enzymes are already used in many biotechnological applications requiring high activity at mild temperatures or fast heat-inactivation rate.
Struvay C, Feller G.
europepmc   +4 more sources

An In-Silico Comparative Study of Lipases from the Antarctic Psychrophilic Ciliate Euplotes focardii and the Mesophilic Congeneric Species Euplotes crassus: Insight into Molecular Cold-Adaptation

Marine Drugs, 2021
Cold-adapted enzymes produced by psychrophilic organisms have elevated catalytic activities at low temperatures compared to their mesophilic counterparts.
Guang Yang, Matteo Mozzicafreddo, Patrizia Ballarini, Sandra Pucciarelli, Cristina Miceli   +4 more
doaj   +1 more source

Psychrophilic enzymes: strategies for cold-adaptation

Essays in Biochemistry, 2023
Abstract Psychrophilic organisms thriving at near-zero temperatures synthesize cold-adapted enzymes to sustain cell metabolism. These enzymes have overcome the reduced molecular kinetic energy and increased viscosity inherent to their environment and maintained high catalytic rates by development of a diverse range of structural ...
Collins, Tony, Feller, Georges
openaire   +2 more sources

Comprehensive insights on environmental adaptation strategies in Antarctic bacteria and biotechnological applications of cold adapted molecules

Frontiers in Microbiology, 2023
Climate change and the induced environmental disturbances is one of the major threats that have a strong impact on bacterial communities in the Antarctic environment.
Kesava Priyan Ramasamy, Lovely Mahawar, Raju Rajasabapathy, Kottilil Rajeshwari, Cristina Miceli, Sandra Pucciarelli   +5 more
doaj   +1 more source

Molecular characterization of cold adaptation of membrane proteins in the Vibrionaceae core-genome. [PDF]

PLoS ONE, 2012
Cold-adaptation strategies have been studied in multiple psychrophilic organisms, especially for psychrophilic enzymes. Decreased enzyme activity caused by low temperatures as well as a higher viscosity of the aqueous environment require certain ...
Tim Kahlke, Steinar Thorvaldsen
doaj   +1 more source

Cold-Active β-Galactosidases: Insight into Cold Adaptation Mechanisms and Biotechnological Exploitation

Marine Drugs, 2021
β-galactosidases (EC 3.2.1.23) catalyze the hydrolysis of β-galactosidic bonds in oligosaccharides and, under certain conditions, transfer a sugar moiety from a glycosyl donor to an acceptor.
Marco Mangiagalli, Marina Lotti
doaj   +1 more source

CCA-addition in the cold: Structural characterization of the psychrophilic CCA-adding enzyme from the permafrost bacterium Planococcus halocryophilus

Computational and Structural Biotechnology Journal, 2021
CCA-adding enzymes are highly specific RNA polymerases that add and maintain the sequence C-C-A at tRNA 3‘-ends. Recently, we could reveal that cold adaptation of such a polymerase is not only achieved at the expense of enzyme stability, but also at the ...
Raphaël de Wijn, Kévin Rollet, Felix G.M. Ernst, Karolin Wellner, Heike Betat, Mario Mörl, Claude Sauter   +6 more
doaj   +1 more source

Cold-Active Enzymes and Their Potential Industrial Applications—A Review

Molecules, 2022
More than 70% of our planet is covered by extremely cold environments, nourishing a broad diversity of microbial life. Temperature is the most significant parameter that plays a key role in the distribution of microorganisms on our planet.
Burhan Hamid, Zaffar Bashir, Ali Mohd Yatoo, Fayaz Mohiddin, Neesa Majeed, Monika Bansal, Peter Poczai, Waleed Hassan Almalki, R. Z. Sayyed, Ali A. Shati, Mohammad Y. Alfaifi   +10 more
doaj   +1 more source

Structure analysis of a new psychrophilic marine protease. [PDF]

PLoS ONE, 2011
A new psychrophilic marine protease was found from a marine bacterium Flavobacterium YS-80 in the Chinese Yellow Sea. The protease is about 49 kD with an isoelectric point about 4.5.
Si-Cai Zhang, Mi Sun, Tang Li, Qi-Hai Wang, Jian-Hua Hao, Yi Han, Xiao-Jian Hu, Ming Zhou, Sheng-Xiang Lin   +8 more
doaj   +1 more source

Computational Analysis of Thermal Adaptation in Extremophilic Chitinases: The Achilles’ Heel in Protein Structure and Industrial Utilization

Molecules, 2021
Understanding protein stability is critical for the application of enzymes in biotechnological processes. The structural basis for the stability of thermally adapted chitinases has not yet been examined.
Dale L. Ang, Mubasher Zahir Hoque, Md. Abir Hossain, Gea Guerriero, Roberto Berni, Jean-Francois Hausman, Saleem A Bokhari, Wallace J. Bridge, Khawar Sohail Siddiqui   +8 more
doaj   +1 more source