Results 61 to 70 of about 8,569 (252)
Biotechnology Journal, Volume 19, Issue 11, November 2024.Graphical Abstract and Lay Summary Colorectal cancer treatment (CRC) is challenged by multi‐drug resistance, where cancer cells become resistant to multiple drugs due to efflux pumps or enzymatic detoxification. This study proposes a multi‐pronged approach utilizing PAMAM dendrimers for targeted co‐delivery of genes and drugs to combat CRC.
Bünyamin Bulkurcuoğlu +7 more
wiley +1 more source
Neopterin-induced Suppression of Erythropoietin Production In Vitro
Pteridines, 1995 The production of neopterin increases in several diseases with activation of the ceIlular immune response. As previously shown serum concentrations of neopterin are inversely correlated with blood hemoglobin concentrations in the anemia of hematological ...
Schobersberger W. +5 more
doaj +1 more source
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 341, Issue 9, Page 1041-1052, November 2024.Abstract Common wall lizards (Podarcis muralis) in Italy show a striking variation in body coloration across the landscape, with highly exaggerated black and green colors in hot and dry climates and brown and white colors in cool and wet climates. Males are more intensely colored than females, and previous work has suggested that the maintenance of ...
Maravillas Ruiz Miñano +5 more
wiley +1 more source
Urinary and Serum Pteridines in Liver Diseases
Pteridines, 1996 The aim of this mini-review is to show the usefulness of pteridines as clinical markers. We assayed urinary neopterin and xanthopterin levels in liver disease. Total pterins were oxidized by active carbon to yield xanthopterin.
Mazda Toshio +2 more
doaj +1 more source
Pteridines and the function of the photosynthetic reaction center.
Proceedings of the National Academy of Sciences of the United States of America, 1969 The photoreduction and interaction with the photosynthetic "reaction center" of 2-amino,4-hydroxy-6-substituted pteridine indicates that these low-potential ( approximately -0.7 v), naturally occurring compounds play a primary role in photosynthetic ...
R. Fuller, N. A. Nugent
semanticscholar +1 more source
Folate, neopterin and kynurenine pathway in patients with statin therapy
Pteridines, 2016 Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes.
Palabiyik Saziye Sezin +9 more
doaj +1 more source
Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry
Pteridines, 1993 Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
doaj +1 more source
6-Acetonylisoxanthopterin: A Potent Inhibitor of Sepiapterin Reductase
Pteridines, 1991 The inhibitory effect of 6-/7-substituted (2'-oxo) pteridines and ichthyopterin was examined for sepiapterin reductase. 6-Acetonylisoxanthopterin and 6-acetonyl-2,4-diamino-7-hydroxypteridine showed pronounced competitive inhibitory effects to ...
Nakanishi A. +3 more
doaj +1 more source
An in vitro System for Studying Pteridine Biosynthesis In Drosophila melanogaster
Pteridines, 1991 In vitro organ culture is a system especially useful for the study of metabolic pathways and their regulation. This report applies such a system to the study of the biosynthesis of pteridines in Drosophila melanogaster, determining in vitro optimal ...
Escriche B., Silva F. J.
doaj +1 more source
Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines. [PDF]
RSC Adv, 2023 Naikoo RA +4 more
europepmc +1 more source