Results 61 to 70 of about 8,074 (264)

Release of Neopterin, PMN Elastase and Terminal Complement Complexes by Orthotopic Liver Transplantation with and without the Use of Veno-venous Bypass

Pteridines, 1998
Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H., Rønholm E., Bengtson JP, Bengtsson A.   +3 more
doaj   +1 more source

Crystal structure of a short‐chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid

Acta Crystallographica Section F, Volume 80, Issue 12, Page 348-355, December 2024.
The structure of B. cenocepacia short‐chain dehydrogenase/reductase (SDR) in complex with NADP+ and benzoic acid is presented. Analysis of the structure reveals a distinctive active‐site architecture, suggesting that this protein is part of the divergent SDR subgroup.Burkholderia cenocepacia is an opportunistic human pathogen that can cause lethal ...
Kafi K. J. Belfon, Olive Beyer, Jan Abendroth, David M. Dranow, Donald D. Lorimer, Ariel Abramov, Yazmine Latimore, Connor Hamilton, Aniah Dawkins, Isabella Hinojosa, Xavier Martinez, Sofia Mirabel, Miriam Duncan, Reagan Womack, Lillian Hicks, Zachary R. Turlington, Thomas E. Edwards, Andrew T. Torelli, Katherine A. Hicks, Jarrod B. French   +19 more
wiley   +1 more source

CRISPR/Cas9‐mediated genome editing of Frankliniella occidentalis, the western flower thrips, via embryonic microinjection

Insect Molecular Biology, Volume 33, Issue 6, Page 589-600, December 2024.
A robust methodology was developed to generate heritable mutations in a thysanopteran crop pest and virus vector (Frankliniella occidentalis, Fo) using the CRISPR/Cas9 system Two eye colour genes (Fo‐white and Fo‐cinnabar) were identified in the F. occidentalis genome to serve as targets of gene knockout with visible changes in eye pigmentation CRISPR ...
Jinlong Han, William Klobasa, Lucas de Oliveira, Dorith Rotenberg, Anna E. Whitfield, Marcé D. Lorenzen   +5 more
wiley   +1 more source

A Twenty Year Association with Pteridines - Chemistry, Biochemistry and Molecular Biology

Pteridines, 1998
The author has summarised the science in his published works which contained chemistry. biochemistry and molecular biology related to pteridines as a dedication to Professor Wolfgang Pfleiderer on the occasion of his seventieth birthday.
Armarego Wilfred L. F.
doaj   +1 more source

Synthesis of 4‐(Phenylamino)quinazoline‐2(1H)‐thiones Using Green Solvents

Chemistry – A European Journal, Volume 30, Issue 63, November 12, 2024.
Environmentally friendly process for synthesizing heterocyclic molecules of therapeutic interest with the quinazoline‐2(1H)‐thione core structure, using bio‐based recyclable solvents. Abstract Given the importance of quinazolines and quinazolinethiones in therapeutic and Food and Drug Administration (FDA)‐approved molecules, we thought interesting to ...
Gatien Messire, Claudie Adolf, Sabine Berteina‐Raboin   +2 more
wiley   +1 more source

First Synthesis of a Natural Isoxanthopterin Glycoside, Asperopterin-A [PDF]

, 2012
The key precursor, N-2-(N,N-dimethylaminomethylene)-6-hydroxymethy1-8-methyl-3[2-(4-nitrophenypethyl]-7-xanthopterin (9) was efficiently prepared from 2,5-diamino-6-methylam1no-3H-pyrimidin-4-one (3) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Ejiri, Kazumasa, Hanaya, Tadashi, Yamamoto, Hiroshi   +2 more
core   +1 more source

Multifunctional PAMAM Dendrimers Carrying SAHA, 5‐FU, and a Therapeutic Gene for Targeted Co‐Delivery Toward Colorectal Cancer Cells

Biotechnology Journal, Volume 19, Issue 11, November 2024.
Graphical Abstract and Lay Summary Colorectal cancer treatment (CRC) is challenged by multi‐drug resistance, where cancer cells become resistant to multiple drugs due to efflux pumps or enzymatic detoxification. This study proposes a multi‐pronged approach utilizing PAMAM dendrimers for targeted co‐delivery of genes and drugs to combat CRC.
Bünyamin Bulkurcuoğlu, Mustafa Ulvi Gürbüz, Silvia Tyciakova, Kristina Pavlov, Nikoleta Mojzesova, Miroslava Matuskova, Metin Tülü, Şebnem Erçelen   +7 more
wiley   +1 more source

A Modified Microbiological Method for Determination of Folate Levels in Erythrocyte and Plasma

Pteridines, 2007
Pteridines are natural heterocyclic compounds and they are generally divided into two main groups which are denominated as conjugated and unconjugated pteridines.
Sipahi Hande, Baydar Terken, Ozalp Meral, Sahin Gonul   +3 more
doaj   +1 more source

Sexual color ornamentation, microhabitat choice, and thermal physiology in the common wall lizard (Podarcis muralis)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 341, Issue 9, Page 1041-1052, November 2024.
Abstract Common wall lizards (Podarcis muralis) in Italy show a striking variation in body coloration across the landscape, with highly exaggerated black and green colors in hot and dry climates and brown and white colors in cool and wet climates. Males are more intensely colored than females, and previous work has suggested that the maintenance of ...
Maravillas Ruiz Miñano, Tobias Uller, Amanda K. Pettersen, Andreas Nord, Luisa J. Fitzpatrick, Geoffrey M. While   +5 more
wiley   +1 more source

Neopterin-induced Suppression of Erythropoietin Production In Vitro

Pteridines, 1995
The production of neopterin increases in several diseases with activation of the ceIlular immune response. As previously shown serum concentrations of neopterin are inversely correlated with blood hemoglobin concentrations in the anemia of hematological ...
Schobersberger W., Jelkmann W., Fandrey J., Frede S., Wachter H., Fuchs D.   +5 more
doaj   +1 more source