Results 61 to 70 of about 8,420 (250)
Role of Weak Molecular Interactions in the Mechanism of Action of a Series of Antihelmintics
Different physicochemical properties such as solute-solute and solute-solvent interactions, tautomerism, lipophilicity and solubility in water were determined for a serie of 6,7-diaryl-pteridines in order to relate those properties with their nematocide ...
Marisa Santo +7 more
doaj +1 more source
Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin [PDF]
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Linscheid, Philippe +4 more
core
2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10).
Döring Thomas +2 more
doaj +1 more source
A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]
Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M +2 more
core +3 more sources
Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design [PDF]
Joanna Panecka-Hofman, Ina Poehner
openalex +1 more source
Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review
ABSTRACT Catalytic hydrogenation refers to the (often) metal‐mediated addition of dihydrogen (H2) equivalents to unsaturated compounds to form new element‐hydrogen bonds. This conceptually simple reaction is ubiquitous in the production of a vast number of essential chemicals.
Esteban Garcia‐Torres +1 more
wiley +1 more source
Mutationen im PTS-Gen und mögliche Auswirkungen auf Funktion und Struktur der 6-Pyruvoyl-Tetrahydropterin-Synthase [PDF]
Background: Research on Juvenile Idiopathic Arthritis (JIA) should support patients, caregivers/parents (carers) and clinicians to make important decisions in the consulting room and eventually to improve the lives of patients with JIA.
Armbrust, Wineke +24 more
core +9 more sources
Neopterin, as a non-conjugated pteridine, is synthesized from guanosine triphosphate and its production is upregulated upon the activation of cellular immune response.
Girgin Gözde +5 more
doaj +1 more source
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro +7 more
wiley +1 more source
A Twenty Year Association with Pteridines - Chemistry, Biochemistry and Molecular Biology
The author has summarised the science in his published works which contained chemistry. biochemistry and molecular biology related to pteridines as a dedication to Professor Wolfgang Pfleiderer on the occasion of his seventieth birthday.
Armarego Wilfred L. F.
doaj +1 more source

