Leveraging the Power of Enzymes in Engineered Dead and Living Materials
Advanced Functional Materials, Volume 34, Issue 44, October 29, 2024.Insights gained during the design of functional enzyme materials have immense potential to supercharge the nascent Engineered Living Material (ELM) field. In this review, these impressive material design strategies are unpacked and contrasted with the enzyme‐control systems used by microorganisms.
Mark R. Shannon +2 more
wiley +1 more source
Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase [PDF]
, 1986 The structure of the complex between E. coli (RT500) form I dihydrofolate reductase, the antibacterial trimethoprim and NADPH has been determined by X-ray crystallography. The inhibitor and cofactor are in mutual contact.
Beddell, C.R. +2 more
core +1 more source
Urinary and Serum Pteridines in Liver Diseases
Pteridines, 1996 The aim of this mini-review is to show the usefulness of pteridines as clinical markers. We assayed urinary neopterin and xanthopterin levels in liver disease. Total pterins were oxidized by active carbon to yield xanthopterin.
Mazda Toshio +2 more
doaj +1 more source
Folate, neopterin and kynurenine pathway in patients with statin therapy
Pteridines, 2016 Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes.
Palabiyik Saziye Sezin +9 more
doaj +1 more source
Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry
Pteridines, 1993 Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
doaj +1 more source
Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines. [PDF]
RSC Adv, 2023 Naikoo RA +4 more
europepmc +1 more source
Synthetic studies on pterin glycosides: the first synthesis of 2′-O-(α-d-glucopyranosyl)biopterin [PDF]
, 2009 L-Rhamnose was led, in a 14-step-sequence, to N2-(N,N-dimethylaminomethylene)-1′-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (23), an appropriately protected precursor for 2′-O-glycosylation, while 4,6-di-O-acetyl-2,3-di-O-(4-methoxybenzyl)-α-
Cha +39 more
core +1 more source
6-Acetonylisoxanthopterin: A Potent Inhibitor of Sepiapterin Reductase
Pteridines, 1991 The inhibitory effect of 6-/7-substituted (2'-oxo) pteridines and ichthyopterin was examined for sepiapterin reductase. 6-Acetonylisoxanthopterin and 6-acetonyl-2,4-diamino-7-hydroxypteridine showed pronounced competitive inhibitory effects to ...
Nakanishi A. +3 more
doaj +1 more source
Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]
, 2017 As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad +3 more
core
An histochemical and ultrastructural analysis of the dermal chromatophores of the variant ranid blue frog [PDF]
, 1970 Integument from blue and green areas of the variant blue frog were analyzed biochemically for pteridines and carotenoids. Solvent extraction and absorption spectrophotometry indicated that Β carotene was greatly reduced in the blue skin, and present in ...
Bagnara, Berns, Berns, Fox, Liu, Martof
core +1 more source