Results 71 to 80 of about 92,751 (208)

Gene structure, transcripts and calciotropic effects of the PTH family of peptides in Xenopus and chicken

BMC Evolutionary Biology, 2010
Background Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) belong to a family of endocrine factors that share a highly conserved N-terminal region (amino acids 1-34) and play key roles in calcium homeostasis, bone formation and skeletal ...
Power Deborah M, Fuentes Juan, Gomes Ana S, Cardoso João CR, Pinheiro Pedro LC, Canário Adelino VM   +5 more
doaj   +1 more source

Structure of a novel PTH-related peptide hPTH' and its interaction with the PTH receptor

, 2012
We have previously shown that a recombinant human PTH fragment, Pro-Pro-[Arg11] hPTH (134)-Pro-Pro-Asp (hPTH'), could be a potentially better and more cost-effective therapeutic agent than PTH (134) on osteoporosis.
Liu, Jingjing, You, Qidong, Feng, Jao, Lin, Donghai, Lin, Kejiang, 林东海, Len, Yonggan, Gao, Hongchang   +7 more
core   +1 more source

Study of the combined effects of PTH treatment and mechanical loading in postmenopausal osteoporosis using a new mechanistic PK-PD model

, 2020
One of only a few approved and available anabolic treatments for severe osteoporosis is daily injections of PTH (1-34). This drug has a specific dual action which can act either anabolically or catabolically depending on the type of administration, i.e ...
Pivonka, Peter, Cooper, David M. L., Trichilo, Silvia, Scheiner, Stefan, Forwood, Mark R, Lavaill, Maxence, Forwood, Mark R., Cooper, David ML   +7 more
core   +1 more source

Exploring naturally occurring clinical subgroups of post-traumatic headache

The Journal of Headache and Pain, 2020
Objective To explore naturally occurring clinical subgroups of post-traumatic headache. Background Persistent post-traumatic headache (PTH) is defined as a headache developing within 7 days of an injury that lasts for greater than 3 months.
T. L. H. Chan, Y. W. Woldeamanuel
doaj   +1 more source

FGF23 Levels, in Patients on Maintenance Hemodialysis, Stage III&IV Chronic Kidney Disease Patients, Post Renal Transplant Recipients and in Normal Individuals

Indian Journal of Transplantation
Introduction: Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone with a significant role in chronic kidney disease (CKD). Serum FGF23 was compared with estimated glomerular filtration rate (eGFR) among CKD patients, renal transplant recipients,
Ramapriya Rengaswamy, Anuradha S. Raman
doaj   +1 more source

Parathyroid Hormone Measurement in Chronic Kidney Disease: From Basics to Clinical Implications

International Journal of Nephrology, 2019
Accurate measurement of parathyroid hormone (PTH) is crucial for therapeutic decision-making in patients with chronic kidney disease-mineral and bone disorder (CKD-MBD).
Kittrawee Kritmetapak, Chatlert Pongchaiyakul   +1 more
doaj   +1 more source

Neural plasticity impairment in chronic post-surgical hypoparathyroidism: a cross-sectional and prospective pilot study

Endocrine Connections
Background: Despite adequate conventional therapy, patients with chronic post-surgical hypoparathyroidism (HypoPT) frequently report persistent physical, emotional, and cognitive symptoms that affect quality of life, despite no overt cognitive impairment.
Andrea Palermo, Gaia Tabacco, Anda Mihaela Naciu, Eleonora Sargentini, Monica Cereghino, Gabriella Musumeci, Maria Valeria Di Lazzaro, Mariagrazia Rossi, Davide Norata, Antonio Todisco, Licia Maria Celani, Alessandro Cruciani, Giulia Massa Rolandino, Francesco Motolese, Fioravante Capone   +14 more
doaj   +1 more source

Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34).

, 2011
Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited.
Dengshun Miao, Feng Yuxu, Goltzman David, Shu Lei, Bo Liu, Karaplis Andrew, Cao Xiaojian, Xiaojian Cao, Miao Dengshun, Ren Yongxin, Yuxu Feng, David Goltzman, Yongxin Ren, Liu Bo, Lei Shu, Andrew Karaplis   +15 more
core   +1 more source

A IMPORTÂNCIA DO ENFERMEIRO NAVEGADOR EM ONCOHEMATOLOGIA

Hematology, Transfusion and Cell Therapy
Introdução: O câncer atualmente é visto como um problema de saúde pública no cenário mundial devido ao impacto expressivo na expectativa e qualidade de vida, justificado pelo envelhecimento populacional acompanhado de estilo de vida pouco saudável e das ...
ER Cavalcante, PTH Silva, TMR Guimarães
doaj   +1 more source

Urban land ownership and the housing question in Germany: Insights from Catholic social ethics

Verbum et Ecclesia
As one measure to combat the housing affordability crisis, land policy is once again receiving more attention. However, it is little known that Catholic social ethicists in Germany were also heavily involved in urban land policy debates between 1950 and ...
Julian Degan
doaj   +1 more source