Results 11 to 20 of about 10,062 (208)
Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3
eLife, 2023 Streptococcus pneumoniae is a major pathogen in children, elderly subjects, and immunodeficient patients. Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule (PRM) involved in resistance to selected microbial agents and in regulation of ...Rémi Porte, Rita Silva-Gomes, Charlotte Theroude, Raffaella Parente, Fatemeh Asgari, Marina Sironi, Fabio Pasqualini, Sonia Valentino, Rosanna Asselta, Camilla Recordati, Marta Noemi Monari, Andrea Doni, Antonio Inforzato, Carlos Rodriguez-Gallego, Ignacio Obando, Elena Colino, Barbara Bottazzi, Alberto Mantovani +17 moredoaj +3 more sourcesPathogen recognition by the long pentraxin PTX3 [PDF]
BioMed Research International, 2011 Innate immunity represents the first line of defence against pathogens and plays key roles in activation and orientation of the adaptive immune response. The innate immune system comprises both a cellular and a humoral arm.F. Moalli, C. Garlanda, Marina Sironi, Jaillon, Sebastien, S. Jaillon, Antonio Inforzato, Moalli, Federica, Barbara Bottazzi, Bottazzi, Barbara, Mantovani, Alberto, Alberto Mantovani, Inforzato, Antonio, Federica Moalli, B. Bottazzi, A. Mantovani, Sebastien Jaillon, Sironi, Marina, A. Inforzato, Cecilia Garlanda, Garlanda, Cecilia, M. Sironi, Sironi M., Inforzato A., Garlanda C., Jaillon S., Mantovani A., Bottazzi B., Moalli F. +27 morecore +6 more sourcesPentraxins and atherosclerosis: the role of PTX3
Current Pharmaceutical Design, 2011 Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cyclic multimeric structure. Based on the primary structure of the subunit, the pentraxins are divided into two groups: short pentraxins ...F. Moalli, Livija Deban, Fabiola Molla, Moalli, Federica, Barbara Bottazzi, Bottazzi, Barbara, Latini, Roberto, Mantovani, Alberto, Alberto Mantovani, Roberto Latini, R. Latini, Federica Moalli, Molla, Fabiola, L. Deban, G. Garlanda, B. Bottazzi, A. Mantovani, F. Molla, Cecilia Garlanda, Garlanda, Cecilia, Deban, Livija +20 morecore +4 more sourcesRegulation of leukocyte recruitment by the long pentraxin PTX3 [PDF]
Nature Immunology, 2010 Pentraxins are a superfamily of conserved proteins involved in the acute-phase response and innate immunity. Pentraxin 3 (PTX3), a prototypical member of the long pentraxin subfamily, is a key component of the humoral arm of innate immunity that is ...F. Moalli, Barbara Rossi, Moalli, Federica, V. Zambelli, Vanessa Zambelli, G. Constantin, M. Sassano, Doni, Andrea, A. Doni, Cuccovillo, Ivan, Remo Castro Russo, Sonia Valentino, M. Gobbi, Sironi M, Zambelli, Vanessa, Russo RC, Cecilia Garlanda, Silvio Danese, Marco Gobbi, Doni A, R. C. Russo, Danese S, C. Garlanda, M. Scanziani, Bastone A, Virgilio Evangelista, B. Rossi, Mantovani, Alberto, Alberto Mantovani, Constantin, Gabriela, Valentino S, I. Cuccovillo, Danese, Silvio, Garlanda C, Sassano M, Giovanni Salvatori, Garlanda, Cecilia, C. Laudanna, Livija Deban, Gobbi, Marco, Marica Sassano, Salvatori, Giovanni, Evangelista, Virgilio, Valentino, Sonia, Federica Moalli, Andrea Doni, L. Deban, A. Bastone, Laudanna, Carlo, V. Evangelista, B. Bottazzi, Carlo Laudanna, G. Salvatori, S. Valentino, Scanziani M, Antonio Bastone, Gobbi M, Bottazzi B, Cuccovillo I, Deban, Livija, Bastone, Antonio, M. Sironi, Mantovani A., Rossi, Barbara, Marina Sironi, Salvatori G, Barbara Bottazzi, Elena Zenaro, Russo, Remo Castro, Zenaro, Elena, Scanziani, Margherita, Bottazzi, Barbara, Moalli F, Deban L, Margherita Scanziani, S. Danese, Gabriela Constantin, A. Mantovani, Sassano, Marica, E. Zenaro, Zambelli V, Ivan Cuccovillo, Sironi, Marina, Evangelista V, Rossi B, Zenaro E, Constantin G, Laudanna C +87 morecore +7 more sourcesAdditional file 1 of Association of PTX3 gene polymorphisms and PTX3 plasma levels with leprosy susceptibility
, 2023 Supplementary Material 1: Figure S1. Association of PTX3 plasma levels (ng/mL) and PTX3 polymorphisms (A) rs1840680 and (B) rs2305619. Statistical significance was determined using the Kruskal-Wallis test.Lorena Viana de Andrade (17585394), Rodrigo Feliciano do Carmo (12971144), Renata Clesia Feitosa Viana da Luz (17585385), Milena Xavier Silva Barbosa (17585391), Anderson da Costa Armstrong (4868704), André Luís Magalhães Fernandes (17585388), Carlos Dornels Freire de Souza (11999362), Ana Clara Cadidé Gonzaga Moraes (17585382) +7 morecore +2 more sourcesRecognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant.
PLoS ONE, 2015 Long pentraxin 3 (PTX3) is a non-redundant component of the humoral arm of innate immunity. The present study was designed to investigate the interaction of PTX3 with Neisseria meningitidis.Barbara Bottazzi, Laura Santini, Silvana Savino, Marzia M Giuliani, Ana I Dueñas Díez, Giuseppe Mancuso, Concetta Beninati, Marina Sironi, Sonia Valentino, Livija Deban, Cecilia Garlanda, Giuseppe Teti, Mariagrazia Pizza, Rino Rappuoli, Alberto Mantovani +14 moredoaj +2 more sourcesThe long pentraxin PTX3 promotes fibrocyte differentiation.
PLOS ONE, 2015 Monocyte-derived, fibroblast-like cells called fibrocytes are associated with fibrotic lesions. The plasma protein serum amyloid P component (SAP; also known as pentraxin-2, PTX2) inhibits fibrocyte differentiation in vitro, and injections of SAP inhibit Vakil, V., Verbeek, J.S., Darrell Pilling, Richard H. Gomer, Varsha Vakil, Richard H Gomer, Cox, N., J Sjef Verbeek, J. Sjef Verbeek, Gomer, R.H., Nehemiah Cox, Pilling, D. +11 morecore +6 more sourcesImpairment of PTX3 expression in osteoblasts: A key element for osteoporosis [PDF]
Cell Death & Disease, 2017 Pentraxin 3 (PTX3) is a multifunctional glycoprotein regulating inflammatory response, cell proliferation and migration and deposition and remodelling of the extracellular matrix by a variety of cells.Giovanni Iolascon, Scimeca, Manuel, Salustri, A, Eleonora Piccirilli, Umberto Tarantino, Brandi M. L., Rinaldi, A, Tancredi V., Annamaria Rinaldi, Nicola Maffulli, Rao C., Gasbarra, Elena, Gasbarra, E, Maffulli, Nicola, Tancredi, Virginia, Feola, M, Nardozi D., Rao, Cecilia, Cecilia Rao, Tarantino U., Scimeca, M, Bonanno, E, Feola, Maurizio, Bonanno, Elena, Elena Gasbarra, Nardozi, Daniela, Rao, C, Maffulli N., Salustri, Antonietta, Brandi, Ml, Daniela Nardozi, Piccirilli E., Elena Bonanno, Iolascon, G, Augusto Orlandi, Tancredi, V, Iolascon, Giovanni, Gasbarra E., Brandi, Maria Luisa, Tarantino, Umberto, Maffulli, N, Piccirilli, E, Iolascon G., Orlandi A., Maurizio Feola, Virginia Tancredi, Nardozi, D, Piccirilli, Eleonora, Rinaldi, Annamaria, Salustri A., Feola M., Tarantino, U, Scimeca M., Manuel Scimeca, Rinaldi A., Bonanno E., Orlandi, A, Maria Luisa Brandi, Antonietta Salustri, Orlandi, Augusto +59 morecore +9 more sources
